公开(公告)号：US5245018A

公开(公告)日：1993-09-14

申请号：US783776

申请日：1991-10-29

申请人： Susumu Kondo ,  Sakae Okano ,  Makoto Azuma

发明人： Susumu Kondo ,  Sakae Okano ,  Makoto Azuma

IPC分类号： A61K51/00 ,  A61K51/08 ,  C07F13/00

CPC分类号： A61K51/08 ,  A61K2123/00

摘要： A process for preparing a radiopharmaceutical composition comprising a technetium 99m chelate complex, comprises the steps of:(1) mixing (a) HSCH.sub.2 CO--NHCH.sub.2 CO--NHCH.sub.2 CO--NHCH.sub.2 COOH (mercaptoacetylglycylglycylglycine, MAG3), (b) a watersoluble reducing agent, (c) a water-soluble stabilizing agent in an amount of not less than 70 mol per 1 mol of the water-soluble reducing agent and (d) a pertechnetate at a pH of about 8 to 11; and(2) heating the resultant mixture at a temperature of about 90 to 140.degree. C.Said process removes any troublesome labeling operation at the diagnostic site and relieve the practitioners from the exposure to radiation during the labeling operation.

公开(公告)号：US5071636A

公开(公告)日：1991-12-10

申请号：US291278

申请日：1988-12-28

申请人： Hirohiko Yamauchi ,  Jun Takahashi ,  Sakae Okano ,  Shigemi Seri ,  Makoto Azuma

发明人： Hirohiko Yamauchi ,  Jun Takahashi ,  Sakae Okano ,  Shigemi Seri ,  Makoto Azuma

IPC分类号： C07C323/25 ,  C07D211/14 ,  C07D295/13 ,  C07F13/00

CPC分类号： C07D295/13 ,  C07C323/25 ,  C07D211/14 ,  C07F13/005

摘要： A polyaminedithiol compound of the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.11 and R.sub.12 are each a lower alkyl group, R.sub.21 is a hydrogen atom or a lower alkyl group, and R.sub.3 and R.sub.13 are each a hydrogen atom or a nitrogen-containing organic group, provided that at least one of R.sub.3 and R.sub.13 is a nitrogen-containing organic group, which is used for imaging of the regional cerebral blood flow.

公开(公告)号：US5831271A

公开(公告)日：1998-11-03

申请号：US633027

申请日：1996-04-16

申请人： Sakae Okano ,  Fumiya Obata ,  Masato Ohya ,  Yoshimasa Tanaka

发明人： Sakae Okano ,  Fumiya Obata ,  Masato Ohya ,  Yoshimasa Tanaka

IPC分类号： G21F1/08 ,  G21F1/12 ,  G21F3/00 ,  G21F5/015 ,  G21F5/018 ,  G21F5/00

CPC分类号： G21F1/12 ,  G21F5/015 ,  G21Y2002/201 ,  G21Y2002/301 ,  G21Y2002/302 ,  G21Y2004/10 ,  G21Y2004/303 ,  G21Y2004/305 ,  G21Y2004/40

摘要： The present invention provides a shielding member for radioactive substances which can be made compact in size and light in weight while maintaining its shielding ability, or improves the shielding ability while keeping the same size, thereby to store a large volume of radioactivity. At the same time, the present invention provides a manufacturing method for the above shielding member and a radioactive solution-producing apparatus using the above shielding member. The radioactive substance-shielding member uses two or more kinds of radiation shielding materials of different shielding abilities. A shielding body made of a shielding material of the highest shielding ability is arranged at an area which is the nearest to a radioactive source.

摘要翻译： 本发明提供一种放射性物质的屏蔽构件，其能够在保持其屏蔽能力的同时保持其屏蔽能力而尺寸和重量轻，或者在保持相同尺寸的同时提高屏蔽能力，从而存储大量的放射性。 同时，本发明提供了上述屏蔽部件的制造方法和使用上述遮蔽部件的放射性溶液制造装置。 放射性物质屏蔽部件使用两种以上不同屏蔽能力的防辐射材料。 由屏蔽能力最强的屏蔽材料制成的屏蔽体布置在离放射源最近的区域。

公开(公告)号：US5716317A

公开(公告)日：1998-02-10

申请号：US352738

申请日：1994-12-02

申请人： Sakae Okano ,  Yoshimasa Tanaka ,  Hisao Tobiki

发明人： Sakae Okano ,  Yoshimasa Tanaka ,  Hisao Tobiki

IPC分类号： A61M5/28 ,  A61M5/178 ,  A61M5/24 ,  A61M5/34 ,  A61B6/00

CPC分类号： A61M5/1785 ,  A61M5/34 ,  A61M5/204 ,  A61M5/24 ,  A61M5/345

摘要： A sheath for a syringe barrel, includes a main body in which a radiation shielding device for holding a syringe filled with pharmaceutical liquid therein is fitted, a male luer provided at a front end of the main body and designed to set a disposable needle, and a transfixing needle extending backward from inside of the male luer to penetrate a rubber plug at an opening at a front end of a syringe held in the main body.

摘要翻译： 用于注射器筒的护套包括：主体，其中装有用于保持装有药物液体的注射器的辐射屏蔽装置，其设置在主体的前端并设计成设置一次性针，并且 从雄性路厄尔的内部向后延伸的穿刺针，以在保持在主体中的注射器的前端的开口处穿透橡胶塞。