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    Oral compositions
    1.
    发明授权
    Oral compositions 有权
    口服成分

    公开(公告)号：US09468225B2

    公开(公告)日：2016-10-18

    申请号：US14179170

    申请日：2014-02-12

    Applicant: Symrise AG

    Inventor： Jakob Ley ,  Sabine Widder ,  Veronika Somoza ,  Barbara Rohm ,  Matthias Zaunschirm ,  Gerhard Krammer

    IPC: A61K31/16 ,  A61K31/164 ,  A23K20/105 ,  A23K1/16 ,  A23L1/29 ,  A23L1/30

    CPC classification number: A23K20/105 ,  A23L33/10 ,  A23L33/30 ,  A61K31/16 ,  A61K31/164

    Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.

    Abstract translation: 建议的是用于口服摄取的新组合物，其包含至少一种来自该组烷酰胺的活性剂。 口服摄入的组合物降低脂肪细胞中游离脂肪酸的摄取量，同时刺激5-羟色胺和多巴胺的释放，这导致食欲降低，饱腹感和积极情绪。 因此，新组合物非常适合抵消任何不希望的重量增益。

    AROMATIC ALKENOIC ACID DERIVATIVES
    2.
    发明申请
    AROMATIC ALKENOIC ACID DERIVATIVES 审中-公开
    芳香酸性衍生物

    公开(公告)号：US20150259319A1

    公开(公告)日：2015-09-17

    申请号：US14644477

    申请日：2015-03-11

    Applicant: Symrise AG

    Inventor： Jakob Ley ,  Katja Obst ,  Katharina Reichelt ,  Veronika Somoza ,  Barbara Rohm

    IPC: C07D317/60 ,  A23L1/30 ,  A23L1/29

    CPC classification number: C07D317/60 ,  A23G1/32 ,  A23G1/42 ,  A23G3/36 ,  A23G3/364 ,  A23L33/10 ,  A23L33/30 ,  A23V2002/00 ,  A61K31/36 ,  A61K31/4525

    Abstract: What are proposed are primarily aromatic alkenoic acid derivatives of the formula I for use in a therapeutic method as (a) means for reducing appetite and/or (b) means for causing a feeling of satiation and/or as (c) means for reducing energy intake and/or as (d) mood enhancers, and the non-therapeutic use of the aromatic alkenoic acid derivatives of formula I as (a) means for reducing appetite and/or (b) means for causing a feeling of satiation and/or as (c) means for reducing energy intake and/or as (d) mood enhancers.

    Abstract translation: 所提出的主要是式I的芳族链烯酸衍生物，用于治疗方法，如（a）减少食欲的手段和/或（b）引起饱腹感的手段和/或作为（c）减少的手段 能量摄入和/或作为（d）情绪增强剂，并且式I的芳族链烯酸衍生物的非治疗用途为（a）用于减少食欲的手段和/或（b）引起饱腹感和/ 或（c）减少能量摄入和/或作为（d）情绪增强剂的方法。

    ORAL COMPOSITIONS
    4.
    发明申请
    ORAL COMPOSITIONS 有权
    口腔组成

    公开(公告)号：US20140234412A1

    公开(公告)日：2014-08-21

    申请号：US14179170

    申请日：2014-02-12

    Applicant: Symrise AG

    Inventor： Jakob Ley ,  Sabine Widder ,  Veronika Somoza ,  Barbara Rohm ,  Matthias Zaunschirm ,  Gerhard Krammer

    IPC: A61K31/16 ,  A23K1/16 ,  A23L1/30

    CPC classification number: A23K20/105 ,  A23L33/10 ,  A23L33/30 ,  A61K31/16 ,  A61K31/164

    Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.

    Abstract translation: 建议的是用于口服摄取的新组合物，其包含至少一种来自该组烷酰胺的活性剂。 口服摄入的组合物降低脂肪细胞中游离脂肪酸的摄取量，同时刺激5-羟色胺和多巴胺的释放，这导致食欲降低，饱腹感和积极情绪。 因此，新组合物非常适合抵消任何不希望的重量增加。

    N-Nonanoylvanillylamine as an agent for reducing the appetite, as an agent for imparting a feeling of fullness and as a mood enhancer, and corresponding substance mixtures, orally consumable products and methods
    5.
    发明申请
    N-Nonanoylvanillylamine as an agent for reducing the appetite, as an agent for imparting a feeling of fullness and as a mood enhancer, and corresponding substance mixtures, orally consumable products and methods 审中-公开
    N-壬酰基乙烯胺作为减轻食欲的药剂，作为赋予丰满感的药剂和作为情绪增强剂的药剂，以及相应的物质混合物，口服消费品和方法

    公开(公告)号：US20130178534A1

    公开(公告)日：2013-07-11

    申请号：US13736414

    申请日：2013-01-08

    Applicant: Symrise AG

    Inventor： Jakob Ley ,  Gerhard Krammer ,  Veronika Somoza ,  Barbara Rohm ,  Mark Somoza

    IPC: A61K31/165 ,  A61K45/06 ,  C07C233/22

    CPC classification number: A61K31/165 ,  A23L33/10 ,  A23L33/17 ,  A23L33/30 ,  A61K45/06 ,  C07C233/22

    Abstract: There is described primarily N-nonanoylvanillylamine for use in a therapeutic method as (a) an agent for reducing the appetite and/or (b) an agent for imparting a feeling of fullness and/or (c) a mood enhancer, as well as the non-therapeutic use of N-nonanoylvanillylamine as (a) an agent for reducing the appetite and/or (b) an agent for imparting a feeling of fullness and/or (c) a mood enhancer. The non-therapeutic use of corresponding substance mixtures is also further described. Finally, the invention relates also to orally consumable products (in particular foodstuffs, feeds and medicaments) comprising N-nonanoylvanillylamine, wherein the N-nonanoylvanillylamine is present in a concentration that (a) reduces the appetite and/or (b) brings about a feeling of fullness and/or (c) enhances the mood, but which concentration is low.

    Abstract translation: 主要描述了用于治疗方法的N-壬酰基乙烯基胺，其为（a）用于降低食欲的药剂和/或（b）赋予饱胀感的药剂和/或（c）心境增强剂，以及 N-壬酰乙烯胺的非治疗用途为（a）降低食欲的药剂和/或（b）赋予饱胀感的药剂和/或（c）心境增强剂。 还进一步描述了相应物质混合物的非治疗用途。 最后，本发明还涉及包含N-壬酰基乙烯基胺的口服消耗品（特别是食品，饲料和药物），其中N-壬酰基乙烯基胺以（a）降低食欲和/或（b）产生 充满感和/或（c）增强情绪，但哪种浓度较低。

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