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公开(公告)号：US07750115B2
公开(公告)日：2010-07-06
申请号：US10594736
申请日：2005-03-28
IPC分类号： C07K7/06
CPC分类号： C07K7/06 , A61K38/00 , C07K5/08 , C07K5/1008 , C07K5/1024
摘要： It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.
摘要翻译： 旨在提供可以相对容易地生产的新型寡肽，不仅具有毛发生长刺激作用，而且还具有促进上皮细胞生长（例如皮肤再生）的作用，并且可以容易地通过角质层 从而到达其效果将被施加的期望靶细胞。 即，含有脯氨酰基异亮氨酰甘氨酰单元或异亮氨酰甘氨酰丝氨酸单元并具有3至7个氨基酸及其水溶性盐的水溶性寡肽。
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公开(公告)号：US20100298235A1
公开(公告)日：2010-11-25
申请号：US12662761
申请日：2010-05-03
CPC分类号： C07K7/06 , A61K38/00 , C07K5/08 , C07K5/1008 , C07K5/1024
摘要： It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.
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公开(公告)号：US08304393B2
公开(公告)日：2012-11-06
申请号：US12662761
申请日：2010-05-03
IPC分类号： A61K38/06
CPC分类号： C07K7/06 , A61K38/00 , C07K5/08 , C07K5/1008 , C07K5/1024
摘要： It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.
摘要翻译： 旨在提供可以相对容易地生产的新型寡肽，不仅具有毛发生长刺激作用，而且还具有促进上皮细胞生长（例如皮肤再生）的作用，并且可以容易地通过角质层 从而到达其效果将被施加的期望靶细胞。 即，含有脯氨酰基异亮氨酰甘氨酰单元或异亮氨酰甘氨酰丝氨酸单元并具有3至7个氨基酸及其水溶性盐的水溶性寡肽。
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公开(公告)号：US20070213276A1
公开(公告)日：2007-09-13
申请号：US10594736
申请日：2005-03-28
CPC分类号： C07K7/06 , A61K38/00 , C07K5/08 , C07K5/1008 , C07K5/1024
摘要： It is intended to provide a novel oligopeptide which can be relatively easily produced, has not only a hair growth-stimulating effect but also an effect of promoting the growth of epithelial cells (for example, skin regeneration) and can easily pass through the horny layer to thereby reach the desired target cells in which its effects are to be exerted. Namely, water-soluble oligopeptides containing a proryl isoleucyl glycyl unit or an isoleucyl glycyl serine unit and having from 3 to 7 amino acids and water-soluble salts thereof.
摘要翻译： 旨在提供可以相对容易地生产的新型寡肽，不仅具有毛发生长刺激作用，而且还具有促进上皮细胞生长（例如皮肤再生）的作用，并且可以容易地通过角质层 从而到达其效果将被施加的期望靶细胞。 即，含有脯氨酰基异亮氨酰甘氨酰单元或异亮氨酰甘氨酰丝氨酸单元并具有3至7个氨基酸及其水溶性盐的水溶性寡肽。
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公开(公告)号：US20060121136A1
公开(公告)日：2006-06-08
申请号：US10522678
申请日：2004-10-28
申请人： Syuichi Oka , Akinori Tsuruda , Yasuhiro Kawano , Susumu Maruyama , Yoshimitsu Yamazaki , Miyuki Kikuchi , Hideaki Ono
发明人： Syuichi Oka , Akinori Tsuruda , Yasuhiro Kawano , Susumu Maruyama , Yoshimitsu Yamazaki , Miyuki Kikuchi , Hideaki Ono
IPC分类号： A61K36/48 , A61K31/715 , C08B37/00
CPC分类号： C07H3/06 , A61K31/7016 , A61K31/702 , A61K36/48 , C07H3/04
摘要： Disclosed is a hypotensive agent that is safe and inexpensive. The agent contains an oligosaccharide that comprises at least one type of hexose and has at least one 1-6 bond.
摘要翻译： 公开了一种安全廉价的降血糖药。 该试剂含有包含至少一种类型的己糖并具有至少一个1-6键的寡糖。
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公开(公告)号：US07820625B2
公开(公告)日：2010-10-26
申请号：US11887766
申请日：2006-03-27
申请人： Syuichi Oka , Akinori Tsuruda
发明人： Syuichi Oka , Akinori Tsuruda
CPC分类号： A61K38/06 , A61K8/64 , A61K38/07 , A61K38/08 , A61Q19/004
摘要： At least one substance selected from the group consisting of a water-soluble peptide comprising at least one unit selected from the group consisting of an isoleucylglycylseryl unit, a prolylisoleucylglycylseryl [SEQ ID NO: 2] unit, a glycylprolylisoleucylglycylseryl [SEQ ID NO: 6] unit, a glycylprolylisoleucylglycylthreonyl [SEQ ID NO: 7] unit, a prolylisoleucylglycyl unit and a glycylprolylisoleucylglycyl [SEQ ID NO: 1] unit and a water-soluble salt thereof can be used as an UV-induced dermatitis inhibitor or atopic dermatitis inhibitor.
摘要翻译： 选自由选自异亮氨酰甘氨酰基单元，脯氨酰基异亮氨酰甘氨酰基丝氨酰基[SEQ ID NO：2]单元，甘氨酰脯氨酰基异亮氨酰甘氨酰丝氨酰基[SEQ ID NO：6]）组成的组中的至少一种的水溶性肽的至少一种物质， 单元，甘氨酰基脯氨酰基脯氨酰基甘氨酰基磺基[SEQ ID NO：7]单元，脯氨酰基异亮氨酰甘氨酰单元和甘氨酰脯氨酰基脯氨酰甘氨酰[SEQ ID NO：1]单元及其水溶性盐可用作UV诱导的皮炎抑制剂或特应性皮炎抑制剂。
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公开(公告)号：US20090215702A1
公开(公告)日：2009-08-27
申请号：US11887766
申请日：2006-03-27
申请人： Syuichi Oka , Akinori Tsuruda
发明人： Syuichi Oka , Akinori Tsuruda
CPC分类号： A61K38/06 , A61K8/64 , A61K38/07 , A61K38/08 , A61Q19/004
摘要： At least one substance selected from the group consisting of a water-soluble peptide comprising at least one unit selected from the group consisting of an isoleucylglycylseryl unit, a prolylisoleucylglycylseryl unit, a glycylprolylisoleucylseryl unit, a glycylprolylisoleucylglycylthreonyl unit, a prolylisoleucylglycyl unit and a glycylprolylisoleucylglycyl unit and a water-soluble salt thereof can be used as an UV-induced dermatitis inhibitor or atopic dermatitis inhibitor.
摘要翻译： 选自由选自异亮氨酰甘氨酰基单元，脯氨酰基异亮氨酰甘氨酰基单元，甘氨酰基脯氨酰基甘氨酰基单元，甘氨酰基脯氨酰基甘氨酰基单元，脯氨酰基异亮氨酰甘氨酰单元和甘氨酰脯氨酰基甘氨酰甘氨酰单元组成的组中的至少一种单元的水溶性肽中的至少一种物质，以及 其水溶性盐可用作UV诱导的皮炎抑制剂或特应性皮炎抑制剂。
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