公开(公告)号：US3772343A

公开(公告)日：1973-11-13

申请号：US3772343D

申请日：1971-12-21

申请人： TAKEDA CHEMICAL INDUSTRIES LTD

发明人： NOGUCHI S ,  KAWAI K ,  KANAI Y ,  TANAYAMA S

IPC分类号： C07C45/70 ,  C07C49/697 ,  C07D317/72 ,  C07C69/76

CPC分类号： C07D317/72 ,  C07C45/70 ,  C07C49/697 ,  Y10S514/825 ,  Y10S514/916

摘要： NOVEL COMPOUNDS OF THE FORMULA

1-(R2-CO-),5-(HO-CYCLOHEXYL),6-R1-INDAN

(WHEREIN R1 IS HYDROGEN OR A HALOGEN AND R2 ISHYDROXY, ALKOXY, AMINO GROUP OR OME IN WHICH ME MEANS A METAL), WHICH ARE USEFUL FOR ANTI-INFLAMMATORIES, ANALGESICS, ANTI-PYRETICS, ANTI-RHEUMATICS, ETC. AND INTERMEDIATES FOR PRODUCTION OF THE ABOVE OBJECTIVE COMPOUNDS, WHICH ARE REPRESENTED BY THE FORMULA

1-(R2-CO-),5-(CYCLOHEXYL),6-R1-INDAN

(WHEREIN THE CYCLOHEXANE RING A HAS A FREE PROTECTED OXO GROUP AND R1 AND R2 HAVE THE MEANING DEFINED ABOVE).

公开(公告)号：US3726878A

公开(公告)日：1973-04-10

申请号：US3726878D

申请日：1970-07-07

申请人： TAKEDA CHEMICAL INDUSTRIES LTD

发明人： KANAI Y ,  HONDA H ,  NOHARA A ,  KANNO M ,  HYOGO K ,  SANNO Y

IPC分类号： C07D213/59 ,  C07D213/68 ,  C07D215/12 ,  C07D31/50

CPC分类号： C07D215/12 ,  C07D213/59 ,  C07D213/68 ,  Y10S514/927

摘要： COMPOUND OF THE FORMULA

2-(R2-N(-R3)-C(=S)-CH2-),(R1)N-PYRIDINE

WHEREIN R1 IS HYDROGEN, LOWER ALKYL, LOWER ALKOXY OR HALOGEN AND N IS AN INTEGER OF 1 TO 4, OR WHEREIN (R1)N IS A DIVALENT STRAIGHT CHAIN HYDROCARBON RADICAL HAVING 4 CARBON ATOMS WHICH IS ATTACHED TO THE 5TH AND 6TH POSITIONS OF THE PYRIDINE RING, EACH OF R2 AND R3 INDEPENDENTLY REPRESENTS HYDROGEN, LOWER ALKYL, ARALKYL OR ARYL, OR R2 AND R3 TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY ARE ATTACHED FORM A HETEOCYCLIC RING WITH A PROVISO THAT AT LEAST ONE OF R1, R2 AND R3 IS OTHER THAN HYDROGEN AND A PHARMACEUTICALLY ACCEPATABLE SALT THEREOF WITH ACIDS.