公开(公告)号：US20250031688A1

公开(公告)日：2025-01-30

申请号：US18361790

申请日：2023-07-28

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Shuxia ZHOU ,  Yana WANG ,  Lan CAO ,  Dayong GAO ,  Qiong XUE ,  Jiusong SUN ,  Huang ZHU

IPC: A01N1/02 ,  A61K39/00 ,  C07K14/54 ,  C07K14/705 ,  C07K14/725 ,  C07K16/28

Abstract: The present disclosure provides, among other things, a cryopreservation medium comprising a cryoprotectant, an albumin, a disaccharide and a non-pyrogenic and isotonic crystalloid solution. The disclosure also provides, among other things, a cryopreservation medium for cryopreserving immune cells, the medium comprising: human serum albumin (HSA), sodium chloride, sodium gluconate, sodium acetate trihydrate, potassium chloride, magnesium chloride, dimethyl sulfoxide (DMSO), and a trehalose. The present disclosure also provides, a method of cryopreserving immune cells, transporting and subsequently administering such immune cells to a patient in need thereof.

公开(公告)号：US20240306632A1

公开(公告)日：2024-09-19

申请号：US18274988

申请日：2022-02-09

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Shuxia ZHOU ,  Yana WANG ,  Lan CAO ,  Dayong GAO ,  Qiong XUE ,  Jiusong SUN ,  Huang ZHU

IPC: A01N1/02

CPC classification number: A01N1/0221 ,  A01N1/0226

Abstract: The present disclosure provides, among other things, a cryopreservation medium comprising a cryoprotectant, an albumin, a disaccharide and a non-pyrogenic and isotonic crystalloid solution. The disclosure also provides, among other things, a cryopreservation medium for cryopreserving immune cells, the medium comprising: human serum albumin (HSA), sodium chloride, sodium gluconate, sodium acetate trihydrate, potassium chloride, magnesium chloride, dimethyl sulfoxide (DMSO), and a trehalose. The present disclosure also provides, a method of cryopreserving immune cells, transporting and subsequently administering such immune cells to a patient in need thereof.