公开(公告)号：US10994013B2

公开(公告)日：2021-05-04

申请号：US14784079

申请日：2014-04-24

Applicant: TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

Inventor： Kalpana N. Thakare ,  David B. Lebo

IPC: A61K47/36 ,  A61K31/192 ,  A61K9/16 ,  A61K9/14 ,  A61K9/50 ,  A61K31/4178 ,  A61K31/427 ,  A61K31/4422 ,  A61K31/496

Abstract: Provided is a dosage form for delivery of a therapeutic agent comprising a polymer matrix comprising arabinogalactan and a therapeutic agent uniformly dispersed in said polymer matrix. In some embodiments, the dosage form is selected from the group consisting of a microsphere, a nanosphere, a powder, a tablet, a film or a pellet enclosed in a capsule. Also provided are methods for preparing the dosage form.

公开(公告)号：US10383825B2

公开(公告)日：2019-08-20

申请号：US15235360

申请日：2016-08-12

Applicant: Temple University-Of The Commonwealth System of Higher Education

Inventor： David B. Lebo ,  Suzan Owaisat

IPC: A61K9/20 ,  A61K9/28 ,  A61K9/00 ,  A61K31/192 ,  A61K31/09 ,  A61K31/522 ,  A61K31/734 ,  A61N1/32

Abstract: An alginate and stearic acid composition is described, including methods of molding it into tablets further comprising a drug, and methods of controlling the drug release from the tablets.

公开(公告)号：US20210212994A1

公开(公告)日：2021-07-15

申请号：US16488250

申请日：2018-02-28

Applicant: Temple University-Of The Commonwealth System of Higher Education

Inventor： David B. Lebo ,  Cong Li

IPC: A61K31/4174 ,  A61K47/20 ,  A61K47/10 ,  A61K9/70 ,  A61K9/00

Abstract: The invention provides an econazole nitrate and thiourea medical patch for the treatment of nail and skin onychomycosis, achieving improved drug penetration, and thus allowing more drug to penetrate into the nail bed and reach the minimum inhibitory concentration.

公开(公告)号：US20190321298A1

公开(公告)日：2019-10-24

申请号：US16459700

申请日：2019-07-02

Applicant: Temple University-Of The Commonwealth System of Higher Education

Inventor： David B. Lebo ,  Suzan Owaisat

IPC: A61K9/20 ,  A61K9/28 ,  A61K31/192 ,  A61K31/734 ,  A61K9/00 ,  A61K31/522 ,  A61K31/09

Abstract: An alginate and stearic acid composition is described, including methods of molding it into tablets further comprising a drug, and methods of controlling the drug release from the tablets.

公开(公告)号：US11351121B2

公开(公告)日：2022-06-07

申请号：US16459700

申请日：2019-07-02

Applicant: Temple University—Of The Commonwealth System of Higher Education

Inventor： David B. Lebo ,  Suzan Owaisat

IPC: A61K9/20 ,  A61K9/00 ,  A61K9/28 ,  A61K31/192 ,  A61K31/522 ,  A61K31/734 ,  A61N1/32 ,  A61K31/09

Abstract: An alginate and stearic acid composition is described, including methods of molding it into tablets further comprising a drug, and methods of controlling the drug release from the tablets.

公开(公告)号：US20170042820A1

公开(公告)日：2017-02-16

申请号：US15235360

申请日：2016-08-12

Applicant: Temple University-Of The Commonwealth System of Higher Education

Inventor： David B. Lebo ,  Suzan Owaisat

IPC: A61K9/20 ,  A61K31/09 ,  A61N1/32 ,  A61K47/36 ,  A61K9/00 ,  A61K31/192 ,  A61K31/522

CPC classification number: A61K9/205 ,  A61K9/0009 ,  A61K9/2013 ,  A61K9/2054 ,  A61K9/2095 ,  A61K9/282 ,  A61K9/286 ,  A61K9/2866 ,  A61K31/09 ,  A61K31/192 ,  A61K31/522 ,  A61K31/734 ,  A61N1/325 ,  A61K2300/00

Abstract: An alginate and stearic acid composition is described, including methods of molding it into tablets further comprising a drug, and methods of controlling the drug release from the tablets.

Abstract translation: 描述了藻酸盐和硬脂酸组合物，包括将其模制成进一步包含药物的片剂的方法，以及从片剂控制药物释放的方法。