公开(公告)号：US20200078395A1

公开(公告)日：2020-03-12

申请号：US16563439

申请日：2019-09-06

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Charles Y.C. PAK ,  Khashayar SAKHAEE ,  Orson W. MOE

IPC: A61K33/06 ,  A61K31/194 ,  A61K9/00 ,  A61K9/08 ,  A61K9/46 ,  A61P13/00

Abstract: Disclosed is the use of an effervescent preparation of calcium and magnesium with additional citric acid in a defined ratio to reduce serum C-carboxy-terminal telopeptide (CTX), increase urinary Mg, increase FEMg, increase urinary citrate, reduce urinary ammonium, and decrease putative serum fibroblast growth factor 23 (FGF23) in subjects taking proton pump inhibitors.