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1.发明申请公开(公告)号：US20200078395A1
公开(公告)日：2020-03-12
申请号：US16563439
申请日：2019-09-06
Inventor： Charles Y.C. PAK , Khashayar SAKHAEE , Orson W. MOE
Abstract: Disclosed is the use of an effervescent preparation of calcium and magnesium with additional citric acid in a defined ratio to reduce serum C-carboxy-terminal telopeptide (CTX), increase urinary Mg, increase FEMg, increase urinary citrate, reduce urinary ammonium, and decrease putative serum fibroblast growth factor 23 (FGF23) in subjects taking proton pump inhibitors.
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公开(公告)号：US20190262376A1
公开(公告)日：2019-08-29
申请号：US16333046
申请日：2017-09-11
Inventor： Connie HSIA , Orson W. MOE , Kytai NGUYEN
IPC: A61K31/711 , C07K14/715 , C12N15/113 , A61K9/51 , A61P11/00 , A61K9/00
Abstract: Provided herein are nanoparticles comprising antisense-encoded erythropoietin receptor (RopE) alone or in combination with erythropoietin receptor (EpoR). Also provided herein are methods of treating or preventing lungs disorders comprising administering RopE alone or in combination with EpoR.
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公开(公告)号：US20180207107A1
公开(公告)日：2018-07-26
申请号：US15742842
申请日：2016-07-08
Inventor： Connie HSIA , Yi HONG , Orson W. MOE , Kytai NGUYEN
IPC: A61K9/51 , A61K9/00 , A61P11/00 , A61K38/47 , A61K31/713
CPC classification number: A61K9/5176 , A61K9/0019 , A61K9/0078 , A61K9/5153 , A61K31/713 , A61K38/47 , A61P11/00 , C12Y302/01031
Abstract: Nanoparticles coated with extracellular matrix (ECM) are provided, in some aspects, for the delivery of a therapeutic protein, nucleic acid, or drug. In some embodiments, the nanoparticles are delivered to a subject via inhalation or aerosol delivery. Also provided, in some aspects, are methods for treating acute lung injury comprising administering α-Klotho (αKlotho) protein or DNA to a subject.
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