公开(公告)号：US10307088B2

公开(公告)日：2019-06-04

申请号：US14794022

申请日：2015-07-08

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Rinat Esenaliev ,  Donald S. Prough ,  Yuriy Petrov ,  Irene Petrov ,  George Saade ,  Gayle L. Olson

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1464 ,  A61B5/1459

Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.

公开(公告)号：US20230233088A1

公开(公告)日：2023-07-27

申请号：US18187614

申请日：2023-03-21

Applicant: Noninvasix, Inc. ,  The Board of Regents of The University of Texas System

Inventor： Rinat ESENALIEV ,  Irene Petrov ,  Yuriy Petrov

IPC: A61B5/00 ,  A61B5/1455

CPC classification number: A61B5/0095 ,  A61B5/14551 ,  A61B2562/0204

Abstract: The systems, devices, and methods herein make optoacoustic measurements and correct or normalize them for variations in optical energy level of the different light pulses used. An optical source directs optical pulses to tissue, an optical energy meter measures the optical energy of the different optical pulses, an acoustic detector measures an acoustic response generated by the tissue in response to the optical pulses, and a processor calculates a concentration of an analyte based on the measured acoustic response and as corrected or normalized for the different energy levels among the optical pulses.

公开(公告)号：US09380967B2

公开(公告)日：2016-07-05

申请号：US14793969

申请日：2015-07-08

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Rinat Esenaliev ,  Donald S. Prough ,  Yuriy Petrov ,  Irene Petrov ,  George Saade ,  Gayle L. Olson

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1464 ,  A61B5/1459

CPC classification number: A61B5/14542 ,  A61B5/0095 ,  A61B5/14553 ,  A61B5/1459 ,  A61B5/1464 ,  A61B5/6814 ,  A61B5/6875 ,  A61B5/742 ,  A61B2562/0271

Abstract: Optoacoustic diagnostic systems, devices, and methods are described. A system may comprise a console unit and a handheld probe. The console unit comprises a controller, a processor, a photodiode array, an acoustic processing subsystem, and a cooling subsystem. The probe directs light signals from the photodiode array to patient tissue. The light signals each have different wavelengths selected based on the physiological parameter of interest. The probe further comprises an acoustic transducer that receives acoustic signals generated in response to the directed light signals. The probe may comprise a finger-held working end that can be directed to the skull of a fetus within the uterus during labor. The probe can then accurately determine blood oxygenation of the fetus to determine if a caesarian section is necessary.

Abstract translation: 描述了光声诊断系统，装置和方法。 系统可以包括控制台单元和手持式探头。 控制台单元包括控制器，处理器，光电二极管阵列，声学处理子系统和冷却子系统。 探针将来自光电二极管阵列的光信号引导到患者组织。 光信号各自具有基于感兴趣的生理参数选择的不同波长。 探头还包括声学换能器，其接收响应于定向光信号而产生的声信号。 探针可以包括手指保持的工作端，其可以在劳动期间被引导到子宫内的胎儿的头骨。 然后，探针可以准确地确定胎儿的血氧饱和度，以确定是否需要剖腹产。