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    Apparatuses and methods for at least partially supporting a valve leaflet of a regurgitant heart valve
    2.
    发明授权
    Apparatuses and methods for at least partially supporting a valve leaflet of a regurgitant heart valve 有权

    公开(公告)号：US10537432B2

    公开(公告)日：2020-01-21

    申请号：US15677470

    申请日：2017-08-15

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Jose L. Navia ,  Samir Kapadia ,  Marwane Berrada

    IPC: A61F2/24

    Abstract: An apparatus for partially supporting a leaflet of a regurgitant heart valve comprises at least one subvalvular device including a subvalvular supporting portion including a leaflet-contacting upper supporter surface longitudinally spaced from an oppositely facing lower supporter surface. A supporter perimeter wall extends longitudinally between the upper and lower supporter surfaces, with at least a portion contacting a subvalvular cardiac wall adjacent to the heart valve. An anchor portion is adjacent to, and longitudinally spaced from, the upper supporter surface. The anchor portion includes a leaflet-contacting lower anchor surface longitudinally spaced from an oppositely facing upper anchor surface. A connector neck is interposed longitudinally between, and is directly attached to both of, the upper supporter surface and the lower anchor surface. The connector neck penetrates longitudinally through at least one of a base of the leaflet and an annulus of the heart valve at a manufactured puncture site.

    Apparatuses and methods for at least partially supporting a valve leaflet of a regurgitant heart valve
    7.
    发明授权
    Apparatuses and methods for at least partially supporting a valve leaflet of a regurgitant heart valve 有权

    公开(公告)号：US11241313B2

    公开(公告)日：2022-02-08

    申请号：US16712059

    申请日：2019-12-12

    Applicant: THE CLEVELAND CLINIC FOUNDATION

    Inventor： Jose L. Navia ,  Samir Kapadia ,  Marwane Berrada

    IPC: A61F2/24

    Abstract: An apparatus for partially supporting a leaflet of a regurgitant heart valve comprises at least one subvalvular device including a subvalvular supporting portion including a leaflet-contacting upper supporter surface longitudinally spaced from an oppositely facing lower supporter surface. A supporter perimeter wall extends longitudinally between the upper and lower supporter surfaces, with at least a portion contacting a subvalvular cardiac wall adjacent to the heart valve. An anchor portion is adjacent to, and longitudinally spaced from, the upper supporter surface. The anchor portion includes a leaflet-contacting lower anchor surface longitudinally spaced from an oppositely facing upper anchor surface. A connector neck is interposed longitudinally between, and is directly attached to both of, the upper supporter surface and the lower anchor surface. The connector neck penetrates longitudinally through at least one of a base of the leaflet and an annulus of the heart valve at a manufactured puncture site.

    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE
    9.
    发明申请
    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE 有权
    装置和方法来达到身体组织

    公开(公告)号：US20150374933A9

    公开(公告)日：2015-12-31

    申请号：US14060274

    申请日：2013-10-22

    Applicant: BAVARIA MEDICAL TECHNOLOGY, CANADA INC. ,  THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia ,  Marwane Berrada ,  Cesar Fuentes-Ortega ,  Daniel Wing Fai Mok

    IPC: A61M5/42

    CPC classification number: A61M5/427 ,  A61B17/3403 ,  A61B17/3478 ,  A61B34/20 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/22069 ,  A61B2017/22095 ,  A61B2017/3405 ,  A61B2017/3411 ,  A61B2017/3488 ,  A61B2018/00279 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/0038 ,  A61B2018/00386 ,  A61B2034/2051

    Abstract: An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member, when deployed into an expanded condition, has a framing member body which includes a three-dimensionally bulbous portion defining a maximum body footprint in a lateral dimension and has longitudinally spaced proximal and distal body ends which are both longitudinally spaced from the maximum body footprint. The proximal body end is attached to the target catheter. A protrusion has a diameter which is smaller than the maximum body footprint diameter. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway is substantially spaced apart from the framing member body.

    Abstract translation: 用于靶向包括患者的第一体腔的壁的身体组织上的所需目标部位的装置包括目标导管。 框架构件在展开状态时具有框架构件主体，该框架构件主体包括三维球形部分，其在侧向尺寸上限定最大身体足迹，并且具有纵向间隔开的近端和远侧主体端部， 身体足迹。 近端体端部附接到目标导管。 突起具有比最大身体足迹直径小的直径。 至少一个目标点由框架构件承载，并适于放置在所需目标位置附近。 至少一个目标通路连接至至少一个目标点。 目标通道的至少一部分与框架构件主体基本间隔开。

    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE
    10.
    发明申请
    APPARATUS AND METHOD FOR TARGETING A BODY TISSUE 有权
    装置和方法来达到身体组织

    公开(公告)号：US20140114246A1

    公开(公告)日：2014-04-24

    申请号：US14060274

    申请日：2013-10-22

    Applicant: BAVARIA MEDICAL TECHNOLOGY, CANADA INC. ,  THE CLEVELAND CLINIC FOUNDATION

    Inventor： Samir Kapadia ,  Marwane Berrada ,  Cesar Fuentes-Ortega ,  Daniel Wing Fai Mok

    IPC: A61M5/42

    CPC classification number: A61M5/427 ,  A61B17/3403 ,  A61B17/3478 ,  A61B34/20 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00252 ,  A61B2017/22069 ,  A61B2017/22095 ,  A61B2017/3405 ,  A61B2017/3411 ,  A61B2017/3488 ,  A61B2018/00279 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/0038 ,  A61B2018/00386 ,  A61B2034/2051

    Abstract: An apparatus for targeting a desired target site on a body tissue comprising a wall of a first body cavity of a patient includes a target catheter. The framing member, when deployed into an expanded condition, has a framing member body which includes a three-dimensionally bulbous portion defining a maximum body footprint in a lateral dimension and has longitudinally spaced proximal and distal body ends which are both longitudinally spaced from the maximum body footprint. The proximal body end is attached to the target catheter. A protrusion has a diameter which is smaller than the maximum body footprint diameter. At least one target point is carried by the framing member and is adapted for placement adjacent the desired target site. At least one target pathway is attached to at least one target point. At least a portion of the target pathway is substantially spaced apart from the framing member body.

    Abstract translation: 用于靶向包括患者的第一体腔的壁的身体组织上的所需目标部位的装置包括目标导管。 框架构件在展开状态时具有框架构件主体，该框架构件主体包括三维球形部分，其在侧向尺寸上限定最大身体足迹，并且具有纵向间隔开的近端和远侧主体端部， 身体足迹。 近端体端部附接到目标导管。 突起具有比最大身体足迹直径小的直径。 至少一个目标点由框架构件承载，并适于放置在所需目标位置附近。 至少一个目标通路连接至至少一个目标点。 目标通道的至少一部分与框架构件主体基本间隔开。

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