公开(公告)号：US12220667B2

公开(公告)日：2025-02-11

申请号：US17645380

申请日：2021-12-21

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Tingwei Ren ,  Woochul Song ,  Yu-Ming Tu

IPC: B01D67/00 ,  B01D69/14 ,  B01D71/24 ,  B01D71/26 ,  B01D71/52 ,  B01D71/56 ,  B01D71/80 ,  C07K14/245 ,  C07K14/31 ,  C07K14/47

Abstract: The present disclosure describes compositions and methods for preparing membrane protein nanosheets and two-dimensional crystals. In particular, the methods employ a solvent. A mixture of a polymer and a membrane protein is solubilized in the solvent, applied to a substrate, and subsequently dried to form the nanosheet or two-dimensional crystal. Applicants have surprisingly found that the membrane proteins maintain their structure when exposed to solvents during the short processing time utilized.

公开(公告)号：US12036515B2

公开(公告)日：2024-07-16

申请号：US17282082

申请日：2019-10-02

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Woochul Song ,  Yue-xiao Shen ,  Chao Lang

IPC: B01D69/12 ,  B01D53/22 ,  B01D67/00 ,  B01D69/02 ,  B01D69/10 ,  B01D71/56 ,  B01D71/60 ,  B01D71/64 ,  B01D71/68 ,  C07C7/144

CPC classification number: B01D69/125 ,  B01D53/228 ,  B01D67/0006 ,  B01D69/02 ,  B01D69/105 ,  B01D71/56 ,  B01D71/60 ,  B01D71/64 ,  B01D71/68 ,  C07C7/144 ,  B01D2325/02 ,  B01D2325/04

Abstract: The present invention relates to a thin-film composite (TFC) membrane composition comprising macrocycles. The invention also relates in part to a method of fabricating a TFC membrane and to a method of using the TFC membrane to separate a desired liquid or gas from a liquid or gas mixture.

公开(公告)号：US11745146B2

公开(公告)日：2023-09-05

申请号：US17448607

申请日：2021-09-23

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Yue-Xiao Shen ,  Woochul Song ,  Tingwei Ren

IPC: B01D69/12 ,  B01D67/00 ,  B01D71/82 ,  B01D69/10 ,  B01D69/14 ,  B01D71/60 ,  B01D71/80 ,  B01D69/02

CPC classification number: B01D69/12 ,  B01D67/0006 ,  B01D67/0093 ,  B01D69/02 ,  B01D69/105 ,  B01D69/125 ,  B01D69/1216 ,  B01D69/144 ,  B01D71/60 ,  B01D71/80 ,  B01D71/82 ,  B01D2323/30 ,  B01D2323/345 ,  B01D2325/14 ,  B01D2325/16

Abstract: The present disclosure describes membrane compositions and methods for preparing membrane compositions. In particular, the methods employ a layer-by-layer approach to membrane preparation. The membrane compositions provide significantly enhanced membrane performance over existing commercial membranes, particularly in terms of permeability and selectivity.

公开(公告)号：US11154822B2

公开(公告)日：2021-10-26

申请号：US16414330

申请日：2019-05-16

Applicant: The Penn State Research Foundation

Inventor： Manish Kumar ,  Yue-Xiao Shen ,  Woochul Song ,  Tingwei Ren

IPC: B01D69/12 ,  B01D67/00 ,  B01D71/82 ,  B01D69/10 ,  B01D69/14 ,  B01D71/60 ,  B01D71/80 ,  B01D69/02

Abstract: The present disclosure describes membrane compositions and methods for preparing membrane compositions. In particular, the methods employ a layer-by-layer approach to membrane preparation. The membrane compositions provide significantly enhanced membrane performance over existing commercial membranes, particularly in terms of permeability and selectivity.

公开(公告)号：US20220118408A1

公开(公告)日：2022-04-21

申请号：US17645380

申请日：2021-12-21

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Tingwei Ren ,  Woochul Song ,  Yu-Ming Tu

IPC: B01D67/00 ,  C07K14/31 ,  C07K14/47 ,  B01D71/80 ,  B01D71/52 ,  B01D71/56 ,  B01D71/24

Abstract: The present disclosure describes compositions and methods for preparing membrane protein nanosheets and two-dimensional crystals. In particular, the methods employ a solvent. A mixture of a polymer and a membrane protein is solubilized in the solvent, applied to a substrate, and subsequently dried to form the nanosheet or two-dimensional crystal. Applicants have surprisingly found that the membrane proteins maintain their structure when exposed to solvents during the short processing time utilized.

公开(公告)号：US20220080364A1

公开(公告)日：2022-03-17

申请号：US17448607

申请日：2021-09-23

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Yue-Xiao Shen ,  Woochul Song ,  Tingwei Ren

IPC: B01D69/12 ,  B01D71/60 ,  B01D67/00 ,  B01D71/82 ,  B01D69/02 ,  B01D69/10 ,  B01D69/14 ,  B01D71/80

Abstract: The present disclosure describes membrane compositions and methods for preparing membrane compositions. In particular, the methods employ a layer-by-layer approach to membrane preparation. The membrane compositions provide significantly enhanced membrane performance over existing commercial membranes, particularly in terms of permeability and selectivity.

公开(公告)号：US20210370240A1

公开(公告)日：2021-12-02

申请号：US17282082

申请日：2019-10-02

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Woochul Song ,  Yue-xiao Shen ,  Chao Lang

IPC: B01D69/12 ,  C07C7/144 ,  B01D69/10 ,  B01D53/22 ,  B01D67/00 ,  B01D71/68 ,  B01D71/56 ,  B01D71/60 ,  B01D71/64 ,  B01D69/02

Abstract: The present invention relates to a thin-film composite (TFC) membrane composition comprising macrocycles. The invention also relates in part to a method of fabricating a TFC membrane and to a method of using the TFC membrane to separate a desired liquid or gas from a liquid or gas mixture.

公开(公告)号：US20190351374A1

公开(公告)日：2019-11-21

申请号：US16414330

申请日：2019-05-16

Applicant: The Penn State Research Foundation

Inventor： Manish Kumar ,  Yue-Xiao Shen ,  Woochul Song ,  Tingwei Ren

IPC: B01D69/12 ,  B01D71/60 ,  B01D71/82 ,  B01D67/00

Abstract: The present disclosure describes membrane compositions and methods for preparing membrane compositions. In particular, the methods employ a layer-by-layer approach to membrane preparation. The membrane compositions provide significantly enhanced membrane performance over existing commercial membranes, particularly in terms of permeability and selectivity.

公开(公告)号：US20240335796A1

公开(公告)日：2024-10-10

申请号：US18750470

申请日：2024-06-21

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Woochul Song ,  SHEN YUE-XIAO ,  Chao Lang

IPC: B01D69/12 ,  B01D53/22 ,  B01D67/00 ,  B01D69/02 ,  B01D69/10 ,  B01D71/56 ,  B01D71/60 ,  B01D71/68 ,  C07C7/144

CPC classification number: B01D69/12 ,  B01D53/228 ,  B01D67/0006 ,  B01D69/02 ,  B01D69/105 ,  B01D69/1251 ,  B01D71/56 ,  B01D71/601 ,  B01D71/68 ,  C07C7/144 ,  B01D2325/04

Abstract: The present invention relates to a thin-film composite (TFC) membrane composition comprising macrocycles. The invention also relates in part to a method of fabricating a TFC membrane and to a method of using the TFC membrane to separate a desired liquid or gas from a liquid or gas mixture.

公开(公告)号：US11235286B2

公开(公告)日：2022-02-01

申请号：US16414517

申请日：2019-05-16

Applicant: THE PENN STATE RESEARCH FOUNDATION

Inventor： Manish Kumar ,  Tingwei Ren ,  Woochul Song ,  Yu-Ming Tu

IPC: B01D67/00 ,  C07K14/31 ,  C07K14/47 ,  B01D71/80 ,  B01D71/52 ,  B01D71/56 ,  B01D71/24 ,  B05D1/02 ,  B05D3/02 ,  B05D1/26 ,  B05D3/00 ,  B05D1/00 ,  B05D1/40

Abstract: The present disclosure describes compositions and methods for preparing membrane protein nanosheets and two-dimensional crystals. In particular, the methods employ a solvent. A mixture of a polymer and a membrane protein is solubilized in the solvent, applied to a substrate, and subsequently dried to form the nanosheet or two-dimensional crystal. Applicants have surprisingly found that the membrane proteins maintain their structure when exposed to solvents during the short processing time utilized.