公开(公告)号：US10286197B2

公开(公告)日：2019-05-14

申请号：US14907679

申请日：2014-07-28

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Jean Pouliot ,  Ken Goldberg ,  I-Chow Hsu ,  J. Adam M. Cunha ,  Animesh Garg ,  Sachin Patil ,  Pieter Abbeel ,  Timmy Siauw

IPC: A61M31/00 ,  A61B8/08 ,  A61B6/03 ,  A61N5/06 ,  A61N5/10 ,  A61N7/02 ,  A61B18/18 ,  A61B18/14 ,  A61B18/00 ,  A61B18/02 ,  B33Y10/00 ,  B33Y80/00 ,  A61B90/00 ,  A61F7/12 ,  B29K101/12 ,  B29L31/00 ,  B29C64/112 ,  B29C64/20

Abstract: The present invention offers an alternative for cancer treatment where radiation, thermotherapy, or another therapeutic modality must be delivered to an internal cavity of a subject, for example to treat mouth, anal, cervical, and vaginal cancers. The invention is a new approach that builds on recent results in 3D printing and steerable needle motion planning to create customized implants containing customized curvature-constrained internal channels that fit securely, minimize air gaps, and precisely guide treatment sources through internal printed channels to accurately reach tumors and minimize damage to healthy tissue.

公开(公告)号：US10702237B2

公开(公告)日：2020-07-07

申请号：US14873467

申请日：2015-10-02

Applicant: The Regents of the University of California

Inventor： Neil Kirby ,  Kamal Singhrao ,  Jean Pouliot

IPC: A61B6/00 ,  A61B6/03 ,  A61N5/10 ,  G09B23/28

Abstract: There is provided a radiographic three-dimensional phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic three-dimensional phantom pair and a theoretical deformation of the radiographic three-dimensional phantom pair. These three-dimensional phantom can be divided into a plurality of portions, and non-radiopaque markers can be added to the portions. The portions of the three-dimensional phantom can be re-assembled, and images of the three-dimensional phantom can be generated and compared.

公开(公告)号：US09398889B2

公开(公告)日：2016-07-26

申请号：US14076747

申请日：2013-11-11

Applicant: The Regents of the University of California

Inventor： Neil Kirby ,  Cynthia Chuang ,  Jean Pouliot

IPC: A61B6/00 ,  A61B6/03 ,  G09B23/28

CPC classification number: A61B6/583 ,  A61B6/032 ,  A61B6/5247 ,  G09B23/286

Abstract: There is provided a radiographic phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic phantom pair and a theoretical deformation of the radiographic phantom pair.

Abstract translation: 在计算机断层摄影扫描中提供了用于特别模拟特定解剖部件的放射照相体模。 提供了各种目的的方法，包括检测射线成像体模对的测量光学变形与射线成像假想对的理论变形之间的差异。

公开(公告)号：US20140294140A1

公开(公告)日：2014-10-02

申请号：US14076747

申请日：2013-11-11

Applicant: The Regents of the University of California

Inventor： Neil Kirby ,  Cynthia Chuang ,  Jean Pouliot

IPC: A61B6/00 ,  A61B6/03

CPC classification number: A61B6/583 ,  A61B6/032 ,  A61B6/5247 ,  G09B23/286

Abstract: There is provided a radiographic phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic phantom pair and a theoretical deformation of the radiographic phantom pair.

Abstract translation: 在计算机断层摄影扫描中提供了用于特别模拟特定解剖部件的放射照相体模。 提供了各种目的的方法，包括检测射线成像体模对的测量光学变形与射线成像假想对的理论变形之间的差异。

公开(公告)号：US20160089106A1

公开(公告)日：2016-03-31

申请号：US14873467

申请日：2015-10-02

Applicant: The Regents of the University of California

Inventor： Neil Kirby ,  Kamal Singhrao ,  Jean Pouliot

IPC: A61B6/00 ,  A61B6/03

Abstract: There is provided a radiographic three-dimensional phantom for inter alia mimicking specific anatomical parts in a computerized tomography scan. Methods are provided for a variety of purposes including detecting a difference between a measured optical deformation of a radiographic three-dimensional phantom pair and a theoretical deformation of the radiographic three-dimensional phantom pair. These three-dimensional phantom can be divided into a plurality of portions, and non-radiopaque markers can be added to the portions. The portions of the three-dimensional phantom can be re-assembled, and images of the three-dimensional phantom can be generated and compared.

Abstract translation: 在计算机断层摄影扫描中提供了用于特别模拟特定解剖部件的放射照相三维体模。 提供了各种目的的方法，包括检测射线照相三维体模对的测量光学变形与射线照相三维体模对的理论变形之间的差异。 这些三维体模可以分成多个部分，并且可以向该部分添加非不透射线的标记。 可以重新组装三维体模的部分，并且可以生成和比较三维体模的图像。