专利检索 ap:("THE REGENTS OF THE UNIVERSITY OF CALIFORNIA") AND inv:"Keelan GUILEY" 第 1 页

1.

发明公开
COMPOSITIONS AND METHODS INVOLVING ENGINEERED P27 审中-公开

公开(公告)号：US20230407274A1

公开(公告)日：2023-12-21

申请号：US18197870

申请日：2023-05-16

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Seth RUBIN , Keelan GUILEY

IPC分类号： C12N9/12 , C07K14/47 , C12Q1/48

CPC分类号： C12N9/12 , C07K14/4738 , C12Q1/485 , C12Y207/11022 , G01N2440/14 , G01N2500/02

摘要： The disclosure provides polypeptides comprising an engineered p27, or a fragment thereof such polypeptides may be used to form trimeric protein complexes with a cyclin-dependent kinase 4 (Cdk4) (or a variant thereof) or Cdk6 (or a variant thereof), and a cyclin D (CycD) or a variant thereof.

2.

发明申请
COMPOSITIONS AND METHODS INVOLVING ENGINEERED P27 有权

公开(公告)号：US20210002619A1

公开(公告)日：2021-01-07

申请号：US16977441

申请日：2019-04-10

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Seth RUBIN , Keelan GUILEY

IPC分类号： C12N9/12 , C12Q1/48 , C07K14/47

摘要： The disclosure provides polypeptides comprising an engineered p27, or a fragment thereof. Such polypeptides may be used to form trimeric protein complexes with a cyclin-dependent kinase 4 (Cdk4) (or a variant thereof) or Cdk6 (or a variant thereof), and a cyclin D (CycD) or a variant thereof.