Patent search ap:("THE REGENTS OF THE UNIVERSITY OF CALIFORNIA") AND inv:"Vivasvan Vykunta" Page 1

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发明申请
COMPOSITIONS AND METHODS FOR MODIFYING A TARGET NUCLEIC ACID 有权

公开(公告)号：US20230112075A1

公开(公告)日：2023-04-13

申请号：US17911387

申请日：2021-03-12

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Alexander Marson , Brian Shy , Justin Eyquem , Vivasvan Vykunta

IPC: C12N15/113 , C07K14/725 , C12N9/22

Abstract: The disclosure provides compositions and methods for for modifying an endogenous cell surface protein (e.g., an endogenous TCR) in a cell (e.g., a T cell) with a CAR or an exogenous protein (e.g., an exogenous intracellular or cell surface protein (e.g., an exogenous TCR)).

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