专利检索 ap:("THE REGENTS OF THE UNIVERSITY OF CALIFORNIA" OR "NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC") AND inv:"Ning SUN" 第 1 页

1.

发明公开
METHODS AND COMPOSITIONS USEFUL FOR THE PRODUCTION OF 4-VINYLPHENOL 审中-公开

公开(公告)号：US20240102057A1

公开(公告)日：2024-03-28

申请号：US18466660

申请日：2023-09-13

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC

发明人： Alberto RODRIGUEZ , Jamie A. MEADOWS , Ning SUN , Blake A. SIMMONS , John M. GLADDEN

IPC分类号： C12P7/22 , C12N9/18

CPC分类号： C12P7/22 , C12N9/18 , C12Y301/01093

摘要： The present invention provides for a method for producing a 4-vinylphenol (4VP) and/or 4-vinylguaiacol (4VG), the method comprising: (a) providing a host cell capable of expressing a polypeptide having a phenolic acid decarboxylase (PAD) enzymatic activity wherein the polypeptide is capable of converting p-coumaric (CA) and/or ferulic acid (FA) into 4-vinylphenol (4VP) and/or 4-vinylguaiacol (4VG), respectively; and (b) culturing the host cell in a culture medium to express the polypeptide such that the polypeptide converts CA and/or FA into 4VP and/or 4VG, respectively; wherein the culture medium comprises an organic overlay or phase.