公开(公告)号：US10267763B2

公开(公告)日：2019-04-23

申请号：US15037809

申请日：2014-12-04

Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN

Inventor： Zhaohui Zhong ,  Girish Kulkarni ,  Karthik Reddy ,  Xudong Fan

IPC: B01D53/02 ,  B82Y30/00 ,  G01N27/414

Abstract: An improved sensing method is provided for rapid analyte detection. The method includes: applying an AC excitation signal to the channel region of the transistor; applying an AC drive signal to the transistor; delivering an analyte of interest to a channel region of a transistor; and monitoring a mixing current of the excitation signal and the drive signal through the transistor, where a change in the mixing current is indicative of the concentration of the analyte of interest.