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公开(公告)号：US11357488B2
公开(公告)日：2022-06-14
申请号：US16751436
申请日：2020-01-24
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Mark A. Wierzbicki , Duncan Maitland , Matthew W. Miller , Andrea D. Muschenborn , Landon Nash , Jason M. Szafron , Todd Landsman
Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.
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公开(公告)号：US20200155131A1
公开(公告)日：2020-05-21
申请号：US16751436
申请日：2020-01-24
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Mark A. Wierzbicki , Duncan Maitland , Matthew W. Miller , Andrea D. Muschenborn , Landon Nash , Jason M. Szafron , Todd Landsman
IPC: A61B17/00
Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.
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Patent Agency Ranking
公开(公告)号：US20190142817A1
公开(公告)日：2019-05-16
申请号：US16249105
申请日：2019-01-16
Applicant: The Texas A&M University System
Inventor： James C. Sacchettini , Matthew W. Miller , Deeann Wallis , Nian E. Zhou , Theresa W. Fossum
IPC: A61K31/454 , A61K45/06 , A61K31/435 , A61K31/427 , A61K31/7048 , A61K47/54 , A61K31/5377
Abstract: Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof in an amount and formulation sufficient to inhibit or induce drug-sensitization in a parasite. The methods can comprise administering a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof to a parasite in an amount and formulation sufficient to inhibit or induce drug-sensitization in the parasite.
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公开(公告)号：US20250143684A1
公开(公告)日：2025-05-08
申请号：US19018495
申请日：2025-01-13
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Mark Wierzbicki , Duncan Maitland , Matthew W. Miller , Andrea D. Muschenborn , Landon Nash , Jason M. Szafron , Todd Landsman
Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.
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公开(公告)号：US12239304B2
公开(公告)日：2025-03-04
申请号：US17837111
申请日：2022-06-10
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Mark A. Wierzbicki , Duncan Maitland , Matthew W. Miller , Andrea D. Muschenborn , Landon Nash , Jason M. Szafron , Todd Landsman
Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.
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公开(公告)号：US20220304667A1
公开(公告)日：2022-09-29
申请号：US17837111
申请日：2022-06-10
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Mark A. Wierzbicki , Duncan Maitland , Matthew W. Miller , Andrea D. Muschenborn , Landon Nash , Jason M. Szafron , Todd Landsman
IPC: A61B17/00
Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.
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公开(公告)号：US10555737B2
公开(公告)日：2020-02-11
申请号：US15567682
申请日：2016-04-22
Applicant: The Texas A&M University System
Inventor： Mark A. Wierzbicki , Duncan Maitland , Matthew W. Miller , Andrea D. Muschenborn , Landon Nash , Jason M. Szafron , Todd Landsman
Abstract: A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.
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