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公开(公告)号：US20140303088A1
公开(公告)日：2014-10-09
申请号：US14251709
申请日：2014-04-14
Applicant: The Texas A&M University System
Inventor： Allison Ficht , Theresa Good , Ken Carson , Sungmun Lee
IPC: C07K14/44
CPC classification number: C07K14/44 , A61K38/00 , C07K14/4702 , C07K14/4711 , C07K2319/35
Abstract: The present invention compositions and methods of using at least a portions of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
Abstract translation: 本发明的组合物和使用至少一部分分离和纯化的α-晶状蛋白多肽的组合物和方法，所述α-晶状体蛋白多肽包含一个或多个复合片，并且可防止神经毒性和淀粉样变。
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公开(公告)号：US09802991B2
公开(公告)日：2017-10-31
申请号：US15073809
申请日：2016-03-18
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Allison Ficht , Theresa Good , Kenneth Carson , Sungmun Lee
CPC classification number: C07K14/44 , A61K38/00 , C07K14/4702 , C07K14/4711 , C07K2319/35
Abstract: The present inventions are compositions and methods of using at least a portion of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
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公开(公告)号：US20160207971A1
公开(公告)日：2016-07-21
申请号：US15073809
申请日：2016-03-18
Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
Inventor： Allison Ficht , Theresa Good , Kenneth Carson , Sungmun Lee
CPC classification number: C07K14/44 , A61K38/00 , C07K14/4702 , C07K14/4711 , C07K2319/35
Abstract: The present inventions are compositions and methods of using at least a portion of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
Abstract translation: 本发明是使用至少一部分分离和纯化的α-晶状蛋白多肽的组合物和方法，所述α-晶状体蛋白多肽包括一个或多个复合片，并且可防止神经毒性和淀粉样变。
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公开(公告)号：US09321817B2
公开(公告)日：2016-04-26
申请号：US14251709
申请日：2014-04-14
Applicant: The Texas A&M University System
Inventor： Allison Ficht , Theresa Good , Kenneth Carson , Sungmun Lee
IPC: A61K38/17 , A61K39/00 , A61K39/002 , C07K14/44 , A61K38/00
CPC classification number: C07K14/44 , A61K38/00 , C07K14/4702 , C07K14/4711 , C07K2319/35
Abstract: The present inventions are compositions and methods of using at least a portion of an isolated and purified α-crystallin polypeptide that includes one or more β-pleated sheets and that prevents neurotoxicity and amyloidogenesis.
Abstract translation: 本发明是使用至少一部分分离和纯化的α-晶状蛋白多肽的组合物和方法，所述α-晶状体蛋白多肽包括一个或多个复合片，并且可防止神经毒性和淀粉样变。
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