公开(公告)号：US11000572B2

公开(公告)日：2021-05-11

申请号：US16671497

申请日：2019-11-01

Applicant: TOKUSHIMA UNIVERSITY

Inventor： Akihito Yamamoto ,  Minoru Ueda ,  Kohki Matsubara ,  Akio Suzumura ,  Koichi Furukawa ,  Yoshihiro Matsushita ,  Hirotaka Wakayama ,  Nobunori Takahashi ,  Shin Tsunekawa ,  Takako Izumoto

IPC: A61K38/19 ,  C12N5/0786 ,  A61K45/06 ,  A61K31/737 ,  A61K38/17

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

公开(公告)号：US10507230B2

公开(公告)日：2019-12-17

申请号：US15938839

申请日：2018-03-28

Applicant: TOKUSHIMA UNIVERSITY

Inventor： Akihito Yamamoto ,  Minoru Ueda ,  Kohki Matsubara ,  Akio Suzumura ,  Koichi Furukawa ,  Yoshihiro Matsushita ,  Hirotaka Wakayama ,  Nobunori Takahashi ,  Shin Tsunekawa ,  Takako Izumoto

IPC: A61K38/19 ,  C12N5/00 ,  C12N5/0786 ,  A61K45/06 ,  A61K31/737 ,  A61K38/17

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.