公开(公告)号：US20250059281A1

公开(公告)日：2025-02-20

申请号：US18598013

申请日：2024-03-07

Applicant: TRUSTEES OF DARTMOUTH COLLEGE

Inventor： Margaret Ackerman ,  Casey Hua ,  Charles Sentman

IPC: C07K16/28 ,  A61K39/00 ,  A61K47/68 ,  A61K51/10 ,  A61P35/00 ,  C07K14/705 ,  C07K14/725 ,  C07K16/46

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

公开(公告)号：US11952425B2

公开(公告)日：2024-04-09

申请号：US17318310

申请日：2021-05-12

Applicant: TRUSTEES OF DARTMOUTH COLLEGE

Inventor： Margaret Ackerman ,  Casey Hua ,  Charles Sentman

IPC: C07K16/28 ,  A61K47/68 ,  A61K51/10 ,  A61P35/00 ,  C07K14/705 ,  C07K14/725 ,  C07K16/46

CPC classification number: C07K16/2827 ,  A61K47/6803 ,  A61K47/6849 ,  A61K51/1027 ,  A61K51/1093 ,  A61P35/00 ,  C07K14/7051 ,  C07K14/70517 ,  C07K14/70521 ,  C07K16/2809 ,  C07K16/468 ,  C07K2317/21 ,  C07K2317/31 ,  C07K2317/56 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/92 ,  C07K2319/02 ,  C07K2319/03 ,  C07K2319/033

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

公开(公告)号：US20210340258A1

公开(公告)日：2021-11-04

申请号：US17318310

申请日：2021-05-12

Applicant: TRUSTEES OF DARTMOUTH COLLEGE

Inventor： Margaret Ackerman ,  Casey Hua ,  Charles Sentman

IPC: C07K16/28 ,  A61K47/68 ,  C07K14/705 ,  C07K16/46 ,  C07K14/725 ,  A61P35/00 ,  A61K51/10

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to 137 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

公开(公告)号：US11034767B2

公开(公告)日：2021-06-15

申请号：US16092681

申请日：2017-04-14

Applicant: Trustees of Dartmouth College

Inventor： Margaret Ackerman ,  Casey Hua ,  Charles Sentman

IPC: C07K16/28 ,  A61K47/68 ,  A61P35/00 ,  A61K51/10 ,  C07K14/725 ,  C07K14/705 ,  C07K16/46

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.

公开(公告)号：US20190127470A1

公开(公告)日：2019-05-02

申请号：US16092681

申请日：2017-04-14

Applicant: Trustees of Dartmouth College

Inventor： Margaret Ackerman ,  Casey Hua ,  Charles Sentman

IPC: C07K16/28 ,  C07K14/725 ,  C07K14/705 ,  C07K16/46 ,  A61K47/68 ,  A61K51/10 ,  A61P35/00

Abstract: Provided herein, in some embodiments, are antibodies, antigen-binding antibody fragments, chimeric antigen receptors (CARs) and bispecific T cell engagers (BiTEs) that bind specifically to B7 homolog 6. Also provided herein are methods of using the same and cells comprising the same.