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公开(公告)号：US10987512B2
公开(公告)日：2021-04-27
申请号：US16194853
申请日：2018-11-19
Applicant: Tusker Medical, Inc.
Inventor： Mahyar Z. Kermani , Bernard H. Andreas , Rohit Girotra , Mansour A. Saleki , Nikhil D. Bhat
Abstract: Various systems and methods provide iontophoretic delivery of anesthesia at a patient's tympanic membrane. Some implementations provide channel switching enabling a single current sink to pull current through two electrodes in an alternating fashion based on clock pulses. The iontophoretic delivery of anesthesia may be driven by an AC modulated current. Some implementations provide for continuous flow of fresh iontophoresis fluid to the ear canal during iontophoresis. The fluid flows from a source reservoir into the cavity between the tympanic membrane and a plug, and then drains out of the cavity to a reservoir. An iontophoresis system may also detect capacitance between an anode electrode and an auxiliary electrode in a patient's ear canal, watching for reduced capacitance to indicate presence of a bubble in the iontophoresis fluid.
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公开(公告)号：US12011587B2
公开(公告)日：2024-06-18
申请号：US17190630
申请日：2021-03-03
Applicant: TUSKER MEDICAL, INC.
Inventor： Mahyar Z. Kermani , Bernard H. Andreas , Rohit Girotra , Mansour A. Saleki , Nikhil D. Bhat
CPC classification number: A61N1/30 , A61F11/00 , A61F11/202 , A61N1/0428 , A61N1/0472 , A61N1/303 , A61N1/325 , A61N1/0526 , A61N1/306
Abstract: Various systems and methods provide iontophoretic delivery of anesthesia at a patient's tympanic membrane. At least one example is a method including: performing iontophoresis within a first ear canal by driving, by a control unit, a DC signal to an electrode of a first iontophoresis device positioned within the first ear canal, the electrode at least partially submerged within an iontophoresis fluid within the first ear canal; measuring, by the control unit, a mixed capacitance associated with the electrode by driving a first AC signal having a first frequency to the electrode; and determining, based on a change in the mixed capacitance, that an air bubble is present in the iontophoresis fluid.
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公开(公告)号：US10130808B2
公开(公告)日：2018-11-20
申请号：US13804491
申请日：2013-03-14
Applicant: Tusker Medical, Inc.
Inventor： Mahyar Z. Kermani , Bernard H. Andreas , Rohit Girotra , Mansour A. Saleki , Nikhil D. Bhat
Abstract: Various systems and methods provide iontophoretic delivery of anesthesia at a patient's tympanic membrane. Some implementations provide channel switching enabling a single current sink to pull current through two electrodes in an alternating fashion based on clock pulses. The iontophoretic delivery of anesthesia may be driven by an AC modulated current. Some implementations provide for continuous flow of fresh iontophoresis fluid to the ear canal during iontophoresis. The fluid flows from a source reservoir into the cavity between the tympanic membrane and a plug, and then drains out of the cavity to a reservoir. An iontophoresis system may also detect capacitance between an anode electrode and an auxiliary electrode in a patient's ear canal, watching for reduced capacitance to indicate presence of a bubble in the iontophoresis fluid.
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