公开(公告)号：US08436312B2

公开(公告)日：2013-05-07

申请号：US12999041

申请日：2008-10-08

申请人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

发明人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

IPC分类号： G01T1/20

CPC分类号： G01T1/1644 ,  G01T1/2008

摘要： This aims to provide a DOI type radiation detector in which scintillation crystals arranged two-dimensionally on a light receiving surface to form rectangular section groups in extending directions of the light receiving surface of a light receiving element are stacked up to make a three-dimensional arrangement and responses of the crystals that have detected radiation are made possible to identify at response positions on the light receiving surface, so that a three-dimensional radiation detection position can be obtained. In the DOI type radiation detector, scintillation crystals are right triangle poles extending upwards from the light receiving surface and the response positions on the light receiving surface are characterized. With this structure, DOI identification of a plurality of layers can be carried out by simply performing an Anger calculation of a light receiving element signal.

摘要翻译： 其目的在于提供一种DOI型放射线检测器，其中，在光接收表面上二维布置的闪烁晶体在光接收元件的光接收表面的延伸方向上形成矩形截面组，以形成三维布置 并且能够检测到辐射的晶体的响应可以在光接收表面上的响应位置处识别，从而可以获得三维辐射检测位置。 在DOI型辐射检测器中，闪烁晶体是从光接收表面向上延伸的直角三角形磁极，并且在光接收表面上的响应位置被表征。 利用这种结构，可以通过简单地执行光接收元件信号的愤怒计算来执行多个层的DOI识别。

公开(公告)号：US20130056638A1

公开(公告)日：2013-03-07

申请号：US13636936

申请日：2010-03-29

申请人： Naoko Inadama ,  Hideo Murayama ,  Taiga Yamaya ,  Mitsuo Watanabe ,  Takahiro Moriya ,  Kenshi Fukumitsu ,  Tomohide Omura

发明人： Naoko Inadama ,  Hideo Murayama ,  Taiga Yamaya ,  Mitsuo Watanabe ,  Takahiro Moriya ,  Kenshi Fukumitsu ,  Tomohide Omura

IPC分类号： G01T1/164

CPC分类号： G01T1/1644

摘要： A three-dimensional position-sensitive radiation detector is provided which has a three-dimensional array of photodetectors disposed on the surface of a scintillator block and which is capable of three-dimensionally identifying the position of light emission at which radiation has been detected within the detector. The three-dimensional position-sensitive radiation detector includes: a scintillator block including a central portion which restricts the direction of diffusion of light so as to direct the light in three axial directions and which has an optically discontinuous region, and an outer portion which is disposed on the outside of the central portion and which does not restrict the direction of diffusion of light; and photodetectors disposed on at least two outer circumferential surfaces of the scintillator block. The detector identifies three-dimensionally the position of light emission, thereby preventing deterioration in position discrimination performance even when inner scintillator elements are smaller than the photodetectors.

摘要翻译： 提供了三维位置敏感的放射线检测器，其具有设置在闪烁体块的表面上的光电检测器的三维阵列，并且能够三维地识别已经在其内检测到辐射的发光的位置 探测器。 三维位置敏感型放射线检测器包括：闪烁体块，其包括限制光的扩散方向的中心部，以使光在三个轴向引导，并具有光学不连续区域;外部部分 设置在中心部分的外侧，并且不限制光的扩散方向; 以及设置在闪烁体块的至少两个外周表面上的光电检测器。 检测器三维地识别发光的位置，从而即使当内部闪烁体元件小于光电检测器时也防止位置判别性能的劣化。

公开(公告)号：US20110024637A1

公开(公告)日：2011-02-03

申请号：US12935016

申请日：2008-04-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Naoko Inadama

发明人： Taiga Yamaya ,  Hideo Murayama ,  Naoko Inadama

IPC分类号： G01T1/161

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： In an open-type PET scanner, detector rings arranged in a multilayered manner in an axial direction are at least partially opened and the thus opened part of the detector rings is at least partially included in a main focus region. Then, at least some of the detecting elements constituting the detector ring are disposed obliquely in the axial direction so that the main sensitivity direction thereof is turned closer to the main focus region, increasing the resolution in the main focus region. Thereby, it is possible to retain resolution in the body axis direction without using a high-resolution DOI detector and to reduce the price of the open-type PET scanner.

摘要翻译： 在开放式PET扫描仪中，以轴向方向多层布置的检测器环至少部分地打开，并且检测器环的这样打开的部分至少部分地包括在主聚焦区域中。 然后，构成检测环的检测元件的至少一部分沿轴向倾斜地设置，使其主感光度方向靠近主聚焦区域，从而提高主聚焦区域中的分辨率。 因此，可以不使用高分辨率DOI检测器来保持体轴方向的分辨率，并且降低开放型PET扫描仪的价格。

公开(公告)号：US20110001049A1

公开(公告)日：2011-01-06

申请号：US12919358

申请日：2008-04-09

申请人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

发明人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

IPC分类号： G01T1/20 ,  G01T1/161

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A light receiver for detecting incident time is installed on the side of a radiation source of a scintillator (including a Cherenkov radiation emitter), and information (energy, incident time, an incident position, etc.) on radiation made incident into the scintillator is obtained by the output of the light receiver. It is, thereby, possible to identify an incident position and others of radiation into the scintillator at high accuracy.

摘要翻译： 用于检测入射时间的光接收器安装在闪烁体（包括切伦科夫辐射发射器）的辐射源的一侧，并且入射到闪烁体中的辐射的信息（能量，入射时间，入射位置等）是 通过光接收器的输出获得。 因此，可以以高精度将入射位置和其他辐射识别到闪烁体中。

公开(公告)号：US09029789B2

公开(公告)日：2015-05-12

申请号：US12919358

申请日：2008-04-09

申请人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

发明人： Kengo Shibuya ,  Taiga Yamaya ,  Naoko Inadama ,  Fumihiko Nishikido ,  Eiji Yoshida ,  Hideo Murayama

IPC分类号： G01T1/202 ,  G01T1/29

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A light receiver for detecting incident time is installed on the side of a radiation source of a scintillator (including a Cherenkov radiation emitter), and information (energy, incident time, an incident position, etc.) on radiation made incident into the scintillator is obtained by the output of the light receiver. It is, thereby, possible to identify an incident position and others of radiation into the scintillator at high accuracy.

摘要翻译： 用于检测入射时间的光接收器安装在闪烁体（包括切伦科夫辐射发射器）的辐射源的一侧，并且入射到闪烁体中的辐射的信息（能量，入射时间，入射位置等）是 通过光接收器的输出获得。 因此，可以以高精度将入射位置和其他辐射识别到闪烁体中。

公开(公告)号：US08933410B2

公开(公告)日：2015-01-13

申请号：US13636936

申请日：2010-03-29

申请人： Naoko Inadama ,  Hideo Murayama ,  Taiga Yamaya ,  Mitsuo Watanabe ,  Takahiro Moriya ,  Kenshi Fukumitsu ,  Tomohide Omura

发明人： Naoko Inadama ,  Hideo Murayama ,  Taiga Yamaya ,  Mitsuo Watanabe ,  Takahiro Moriya ,  Kenshi Fukumitsu ,  Tomohide Omura

IPC分类号： G01T1/20 ,  G01T1/164

CPC分类号： G01T1/1644

摘要： A three-dimensional position-sensitive radiation detector is provided which has a three-dimensional array of photodetectors disposed on the surface of a scintillator block and which is capable of three-dimensionally identifying the position of light emission at which radiation has been detected within the detector. The three-dimensional position-sensitive radiation detector includes: a scintillator block including a central portion which restricts the direction of diffusion of light so as to direct the light in three axial directions and which has an optically discontinuous region, and an outer portion which is disposed on the outside of the central portion and which does not restrict the direction of diffusion of light; and photodetectors disposed on at least two outer circumferential surfaces of the scintillator block. The detector identifies three-dimensionally the position of light emission, thereby preventing deterioration in position discrimination performance even when inner scintillator elements are smaller than the photodetectors.

摘要翻译： 提供了三维位置敏感的放射线检测器，其具有设置在闪烁体块的表面上的光电检测器的三维阵列，并且能够三维地识别已经在其内检测到辐射的发光的位置 探测器。 三维位置敏感型放射线检测器包括：闪烁体块，其包括限制光的扩散方向的中心部，以使光在三个轴向引导，并具有光学不连续区域;外部部分 设置在中心部分的外侧，并且不限制光的扩散方向; 以及设置在闪烁体块的至少两个外周表面上的光电检测器。 检测器三维地识别发光的位置，从而即使当内部闪烁体元件小于光电检测器时也防止位置判别性能的劣化。

公开(公告)号：US07671339B2

公开(公告)日：2010-03-02

申请号：US11658699

申请日：2006-12-25

申请人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

发明人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

IPC分类号： G01T1/164 ,  G01T1/166

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A positron emission tomography (PET) scanner is provided which uses information on the time-of-flight difference (TOF) between annihilation radiations for image reconstruction. The scanner has detection time correction information (memory) corresponding to information on coordinates in a radiation detection element (e.g., scintillator crystal), in the depth and lateral directions, at which an interaction has occurred between an annihilation radiation and the crystal. Reference is made to the detection time correction information, thereby providing information on time-of-flight difference with improved accuracy. As such, an improved signal to noise ratio and spatial resolution are provided for image reconstruction using time-of-flight (TOF) difference.

摘要翻译： 提供了一种正电子发射断层扫描仪（PET）扫描仪，其使用关于图像重建的湮灭辐射之间的飞行时间差（TOF）的信息。 扫描仪具有与在湮灭辐射与晶体之间发生相互作用的深度和横向上的放射线检测元件（例如，闪烁体晶体）中的坐标信息相对应的检测时间校正信息（存储器）。 参考检测时间校正信息，从而提供关于飞行时间差异的信息，提高精度。 因此，为使用飞行时间（TOF）差异的图像重建提供了改善的信噪比和空间分辨率。

公开(公告)号：US20090159804A1

公开(公告)日：2009-06-25

申请号：US11658699

申请日：2006-12-25

申请人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

发明人： Kengo Shibuya ,  Tomoaki Tsuda ,  Fumihiko Nishikido ,  Naoko Inadama ,  Eiji Yoshida ,  Taiga Yamaya ,  Hideo Murayama

IPC分类号： G01T1/164

CPC分类号： G01T1/2985 ,  A61B6/037

摘要： A positron emission tomography (PET) scanner is provided which uses information on the time-of-flight difference (TOF) between annihilation radiations for image reconstruction. The scanner has detection time correction information (memory) corresponding to information on coordinates in a radiation detection element (e.g., scintillator crystal), in the depth and lateral directions, at which an interaction has occurred between an annihilation radiation and the crystal. Reference is made to the detection time correction information, thereby providing information on time-of-flight difference with improved accuracy. As such, an improved signal to noise ratio and spatial resolution are provided for image reconstruction using time-of-flight (TOF) difference.

摘要翻译： 提供了一种正电子发射断层扫描仪（PET）扫描仪，其使用关于图像重建的湮灭辐射之间的飞行时间差（TOF）的信息。 扫描仪具有与在湮灭辐射与晶体之间发生相互作用的深度和横向上的放射线检测元件（例如，闪烁体晶体）中的坐标信息相对应的检测时间校正信息（存储器）。 参考检测时间校正信息，从而提供关于飞行时间差异的信息，提高精度。 因此，为使用飞行时间（TOF）差异的图像重建提供了改善的信噪比和空间分辨率。

公开(公告)号：US20110101229A1

公开(公告)日：2011-05-05

申请号：US12999041

申请日：2008-10-08

申请人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

发明人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

IPC分类号： G01T1/202

CPC分类号： G01T1/1644 ,  G01T1/2008

摘要： This aims to provide a DOI type radiation detector in which scintillation crystals arranged two-dimensionally on a light receiving surface to form rectangular section groups in extending directions of the light receiving surface of a light receiving element are stacked up to make a three-dimensional arrangement and responses of the crystals that have detected radiation are made possible to identify at response positions on the light receiving surface, so that a three-dimensional radiation detection position can be obtained. In the DOI type radiation detector, scintillation crystals are right triangle poles extending upwards from the light receiving surface and the response positions on the light receiving surface are characterized. With this structure, DOI identification of a plurality of layers can be carried out by simply performing an Anger calculation of a light receiving element signal.

摘要翻译： 其目的在于提供一种DOI型放射线检测器，其中，在光接收表面上二维布置的闪烁晶体在光接收元件的光接收表面的延伸方向上形成矩形截面组，以形成三维布置 并且能够检测到辐射的晶体的响应可以在光接收表面上的响应位置处识别，从而可以获得三维辐射检测位置。 在DOI型辐射检测器中，闪烁晶体是从光接收表面向上延伸的直角三角形磁极，并且在光接收表面上的响应位置被表征。 利用这种结构，可以通过简单地执行光接收元件信号的愤怒计算来执行多个层的DOI识别。

公开(公告)号：US08461539B2

公开(公告)日：2013-06-11

申请号：US12996471

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

发明人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

IPC分类号： G01T1/166

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/583 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.

摘要翻译： 组合放射治疗/ PET装置包括：开放式PET装置，其具有多个环形探测器环，所述多环检测器环在体轴方向上彼此相对以在其间留有间隙; 以及用于通过间隙进行放射治疗的放射线治疗装置。 当对X射线，γ射线或粒子束照射受影响的区域进行辐射治疗的受影响区域状况和治疗束进行成像时，该装置覆盖放射治疗的照射场中的感兴趣区域， 开放的PET装置的视野，从而可以定位照射场和使用PET图像的处理监视。