公开(公告)号：US20120165651A1

公开(公告)日：2012-06-28

申请号：US13257526

申请日：2009-03-23

申请人： Taiga Yamaya ,  Eiji Yoshida ,  Fumihiko Nishikido ,  Taku Inaniwa ,  Hideo Murayama

发明人： Taiga Yamaya ,  Eiji Yoshida ,  Fumihiko Nishikido ,  Taku Inaniwa ,  Hideo Murayama

IPC分类号： A61B6/00

CPC分类号： A61N5/1049 ,  A61B6/037 ,  A61N2005/1052 ,  A61N2005/1087 ,  G01T1/1603 ,  G01T1/2985

摘要： An imaging device, or a PET device, opposed gamma camera type PET device, or open PET device in particular, that is combined with a radiation therapy device, in which detectors are rotated to reduce incidence of nuclear fragments on the detectors. For example, in an opposed gamma camera type PET device, beam irradiation and detector rotation can be synchronized to prevent the detectors from interfering with the treatment beam and reduce the incidence of nuclear fragments on the detectors. This makes it possible to reduce the incidence of nuclear fragments on the detectors without interfering with a treatment beam, thereby enabling measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or during irradiation.

摘要翻译： 与成像装置或PET装置相对的γ相机型PET装置或特别是开放的PET装置，其与辐射治疗装置组合，其中检测器被旋转以减少检测器上的核碎片的发生率。 例如，在相对的γ照相机类型的PET装置中，可以同步束照射和检测器旋转，以防止检测器干扰处理束并减少检测器上核碎片的发生。 这使得可以在不干扰处理束的情况下降低检测器上核碎片的发生率，从而能够在照射后或照射期间立即测量湮灭辐射和照射场的三维成像。

公开(公告)号：US20120150018A1

公开(公告)日：2012-06-14

申请号：US13257434

申请日：2009-03-23

申请人： Taiga Yamaya ,  Taku Inaniwa ,  Fumihiko Nishikido ,  Hideo Murayama

发明人： Taiga Yamaya ,  Taku Inaniwa ,  Fumihiko Nishikido ,  Hideo Murayama

IPC分类号： A61B5/055 ,  A61B6/00

CPC分类号： A61N5/1049 ,  A61B6/037 ,  A61N2005/1052 ,  A61N2005/1054 ,  A61N2005/1087 ,  G01T1/2985

摘要： A shielding structure against nuclear fragments (referred to as a shield) is operated according to ON and OFF of beam irradiation so as to reduce incidence of nuclear fragments on detectors during beam irradiation. This enables measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or even during irradiation.

摘要翻译： 根据光束照射的ON和OFF操作针对核碎片的屏蔽结构（称为屏蔽），以减少光束照射期间检测器上核碎片的发生。 这使得能够在照射之后或甚至在照射期间测量湮灭辐射和照射场的三维成像。

公开(公告)号：US08461539B2

公开(公告)日：2013-06-11

申请号：US12996471

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

发明人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

IPC分类号： G01T1/166

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/583 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.

摘要翻译： 组合放射治疗/ PET装置包括：开放式PET装置，其具有多个环形探测器环，所述多环检测器环在体轴方向上彼此相对以在其间留有间隙; 以及用于通过间隙进行放射治疗的放射线治疗装置。 当对X射线，γ射线或粒子束照射受影响的区域进行辐射治疗的受影响区域状况和治疗束进行成像时，该装置覆盖放射治疗的照射场中的感兴趣区域， 开放的PET装置的视野，从而可以定位照射场和使用PET图像的处理监视。

公开(公告)号：US20110092814A1

公开(公告)日：2011-04-21

申请号：US12996471

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

发明人： Taiga Yamaya ,  Hideo Murayama ,  Taku Inaniwa

IPC分类号： A61B6/00

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/583 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.

摘要翻译： 组合放射治疗/ PET装置包括：开放式PET装置，其具有多个环形探测器环，所述多环检测器环在体轴方向上彼此相对以在其间留有间隙; 以及用于通过间隙进行放射治疗的放射线治疗装置。 当对X射线，γ射线或粒子束照射受影响的区域进行辐射治疗的受影响区域状况和治疗束进行成像时，该装置覆盖放射治疗的照射场中的感兴趣区域， 开放的PET装置的视野，从而可以定位照射场和使用PET图像的处理监视。

公开(公告)号：US08581196B2

公开(公告)日：2013-11-12

申请号：US12996443

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

IPC分类号： G01T1/161

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4266 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

摘要翻译： 在通过用X射线，γ射线或粒子束照射受影响区域进行的用于检测通过放射治疗癌症的放射线照射产生的湮灭辐射的光束监测中，提供了检测器移位型组合放射治疗/ PET装置 一种开放的PET装置，包括多个可移动的多环检测器环; 以及能够通过检测器环之间的辐射束照射的放射线照射装置。 该装置改变检测器环的位置，通过检测器环之间的辐射束进行照射，然后执行辐射测量。

公开(公告)号：US20110084211A1

公开(公告)日：2011-04-14

申请号：US12996443

申请日：2008-08-01

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara ,  Taku Inaniwa ,  Takuji Furukawa ,  Shinichirou Mori

IPC分类号： G01T1/161 ,  A61N5/10

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4266 ,  A61N5/1048 ,  A61N2005/1052 ,  A61N2005/1087

摘要： In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

摘要翻译： 在通过用X射线，γ射线或粒子束照射受影响区域进行的用于检测通过放射治疗癌症的放射线照射产生的湮灭辐射的光束监测中，提供了检测器移位型组合放射治疗/ PET装置 一种开放的PET装置，包括多个可移动的多环检测器环; 以及能够通过检测器环之间的辐射束照射的放射线照射装置。 该装置改变检测器环的位置，通过检测器环之间的辐射束进行照射，然后执行辐射测量。

公开(公告)号：US08436312B2

公开(公告)日：2013-05-07

申请号：US12999041

申请日：2008-10-08

申请人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

发明人： Naoko Inadama ,  Hideo Murayama ,  Kengo Shibuya ,  Fumihiko Nishikido ,  Taiga Yamaya ,  Eiji Yoshida

IPC分类号： G01T1/20

CPC分类号： G01T1/1644 ,  G01T1/2008

摘要： This aims to provide a DOI type radiation detector in which scintillation crystals arranged two-dimensionally on a light receiving surface to form rectangular section groups in extending directions of the light receiving surface of a light receiving element are stacked up to make a three-dimensional arrangement and responses of the crystals that have detected radiation are made possible to identify at response positions on the light receiving surface, so that a three-dimensional radiation detection position can be obtained. In the DOI type radiation detector, scintillation crystals are right triangle poles extending upwards from the light receiving surface and the response positions on the light receiving surface are characterized. With this structure, DOI identification of a plurality of layers can be carried out by simply performing an Anger calculation of a light receiving element signal.

摘要翻译： 其目的在于提供一种DOI型放射线检测器，其中，在光接收表面上二维布置的闪烁晶体在光接收元件的光接收表面的延伸方向上形成矩形截面组，以形成三维布置 并且能够检测到辐射的晶体的响应可以在光接收表面上的响应位置处识别，从而可以获得三维辐射检测位置。 在DOI型辐射检测器中，闪烁晶体是从光接收表面向上延伸的直角三角形磁极，并且在光接收表面上的响应位置被表征。 利用这种结构，可以通过简单地执行光接收元件信号的愤怒计算来执行多个层的DOI识别。

公开(公告)号：US08222608B2

公开(公告)日：2012-07-17

申请号：US12936464

申请日：2008-04-14

申请人： Taiga Yamaya ,  Hideo Murayama

发明人： Taiga Yamaya ,  Hideo Murayama

IPC分类号： G01T1/166

CPC分类号： G01T1/2985 ,  A61B6/037 ,  A61B6/4258 ,  A61B6/4266 ,  A61B6/44 ,  A61B6/508

摘要： A PET scanner in which detector rings are arrayed in a multilayered manner so as to oppose each other in the body axis direction is provided. In the PET scanner, a predetermined number of detector units, each of which is made up of a predetermined number of detector rings, are arrayed so as to give each other a clearance, and a first ring set in which the clearance is less than or equal to a mean value of widths of two detector units forming each clearance and a second ring set constituted with a predetermined number of detector units are arrayed apart so as to give a clearance which is less than or equal to a mean value of the width of the first ring set and that of the second ring set, thereby imaging a field-of-view including the clearance and continuing in the body axis direction to an entire length of the first ring set and that of the second ring set.

摘要翻译： 提供了一种PET扫描仪，其中检测器环以多层方式排列成在体轴方向上彼此相对。 在PET扫描器中，排列有预定数量的检测器单元，每个检测器单元由预定数量的检测器环构成，以便彼此给予间隙;第一环组，其中间隙小于或等于 等于形成每个间隙的两个检测器单元的宽度的平均值，并且由预定数量的检测器单元构成的第二环组排列成分开，以便产生小于或等于宽度的平均值的间隙 所述第一环组和所述第二环组的第一环组和所述第二环组的整个长度成像为包括所述间隙的视场，并且在所述体轴方向上延伸到所述第一环组和所述第二环组的整个长度。

公开(公告)号：US20100128956A1

公开(公告)日：2010-05-27

申请号：US12450803

申请日：2007-04-17

申请人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara

发明人： Taiga Yamaya ,  Hideo Murayama ,  Shinichi Minohara

IPC分类号： G06T7/00 ,  G01T1/161 ,  H05G1/60

CPC分类号： A61B6/03 ,  A61B6/037 ,  G01T1/1603 ,  G01T1/1611 ,  G01T1/1615 ,  G01T1/2985

摘要： A plurality of detector rings in which detectors arranged densely or spatially in a ring shape or in a polygonal shape are arranged, with an open space kept in the body axis direction, coincidences are measured for some of or all of detector pairs connecting the detector rings apart from the open space to perform three-dimensional image reconstruction, thereby imaging the open space between the detector rings as a tomographic image. Therefore, the open space is secured, with the deteriorated quality of an image suppressed, thus making it possible to easily gain access to a patient under PET scanning from outside a gantry and also provide irradiation of particle beams for cancer treatment as well as X-ray CT scanning.

摘要翻译： 多个检测器环布置有密集或空间上呈环形或多边形的检测器环，其开放空间保持在体轴方向上，对于连接检测器环的检测器对中的一些或全部测量出一致性 除了执行三维图像重建的开放空间之外，从而将检测器环之间的开放空间成像为断层图像。 因此，确保开放空间，抑制图像质量下降，从而能够容易地从台架外部在PET扫描下进入患者，并且还提供用于癌症治疗的粒子束的照射以及X- 射线CT扫描。

公开(公告)号：US20130056638A1

公开(公告)日：2013-03-07

申请号：US13636936

申请日：2010-03-29

申请人： Naoko Inadama ,  Hideo Murayama ,  Taiga Yamaya ,  Mitsuo Watanabe ,  Takahiro Moriya ,  Kenshi Fukumitsu ,  Tomohide Omura

发明人： Naoko Inadama ,  Hideo Murayama ,  Taiga Yamaya ,  Mitsuo Watanabe ,  Takahiro Moriya ,  Kenshi Fukumitsu ,  Tomohide Omura

IPC分类号： G01T1/164

CPC分类号： G01T1/1644

摘要： A three-dimensional position-sensitive radiation detector is provided which has a three-dimensional array of photodetectors disposed on the surface of a scintillator block and which is capable of three-dimensionally identifying the position of light emission at which radiation has been detected within the detector. The three-dimensional position-sensitive radiation detector includes: a scintillator block including a central portion which restricts the direction of diffusion of light so as to direct the light in three axial directions and which has an optically discontinuous region, and an outer portion which is disposed on the outside of the central portion and which does not restrict the direction of diffusion of light; and photodetectors disposed on at least two outer circumferential surfaces of the scintillator block. The detector identifies three-dimensionally the position of light emission, thereby preventing deterioration in position discrimination performance even when inner scintillator elements are smaller than the photodetectors.

摘要翻译： 提供了三维位置敏感的放射线检测器，其具有设置在闪烁体块的表面上的光电检测器的三维阵列，并且能够三维地识别已经在其内检测到辐射的发光的位置 探测器。 三维位置敏感型放射线检测器包括：闪烁体块，其包括限制光的扩散方向的中心部，以使光在三个轴向引导，并具有光学不连续区域;外部部分 设置在中心部分的外侧，并且不限制光的扩散方向; 以及设置在闪烁体块的至少两个外周表面上的光电检测器。 检测器三维地识别发光的位置，从而即使当内部闪烁体元件小于光电检测器时也防止位置判别性能的劣化。