公开(公告)号：US06645254B1

公开(公告)日：2003-11-11

申请号：US09816347

申请日：2001-03-26

申请人： Takashi Aida ,  Hiroyuki Matsuda ,  Tsunehide Yoneyama ,  Toshimitsu Hagiwara

发明人： Takashi Aida ,  Hiroyuki Matsuda ,  Tsunehide Yoneyama ,  Toshimitsu Hagiwara

IPC分类号： D06L300

CPC分类号： C11D3/50 ,  C11D3/2072 ,  C11D3/3905 ,  C11D3/3947 ,  C11D3/3956

摘要： One or more 1-substituted-2,2,4-trimethylpentane-3-one derivatives represented by the following general formula (1): wherein X represents a benzene ring or a cyclohexane ring; and R represents an arbitrary hydrogen atom on the benzene ring or cyclohexane ring or a methyl group which substitutes the hydrogen atom are incorporated in a bleaching agent composition containing a chlorine-based bleaching agent component such as sodium hypochlorite or oxygen-based bleaching agent component such as sodium perborate.

摘要翻译： 一种或多种由以下通式（1）表示的1-取代-2,2,4-三甲基戊烷-3-酮衍生物：其中X表示苯环或环己烷环; R表示苯环或环己烷环上的任意的氢原子或取代氢原子的甲基，可以含有氯代漂白剂成分如次氯酸钠或氧基漂白剂成分的漂白剂组合物， 作为过硼酸钠。

公开(公告)号：US07538081B2

公开(公告)日：2009-05-26

申请号：US09949718

申请日：2001-09-12

申请人： Kenya Ishida ,  Takashi Nishida ,  Hiroyuki Matsuda ,  Hisao Iwai ,  Toshimitsu Hagiwara

发明人： Kenya Ishida ,  Takashi Nishida ,  Hiroyuki Matsuda ,  Hisao Iwai ,  Toshimitsu Hagiwara

IPC分类号： A61K8/00

CPC分类号： A61Q13/00 ,  A23L2/56 ,  A61K8/34 ,  C11B9/0034

摘要： A fragrance composition having an excellent diffusivity and long-lasting property of fragrance and a cosmetic, toiletry, bath composition, food and drink and pharmaceutical having an excellent diffusivity and long-lasting property of fragrance by using a novel fixative. A compound represented by the following general formula (1) is incorporated in a fragrance composition or the foregoing products. The amount of the compound of the general formula (1) to be incorporated in the fragrance composition is preferably from 0.01 to 90% by weight. The amount of the compound of the general formula (1) to be incorporated directly in the foregoing products is preferably from 0.0001 to 2.0 times (by weight) the weight of the aroma composition and/or composition to be incorporated therein. In this arrangement, a fragrance composition or products having an enhanced diffusivity and long-lasting property of fragrance can be obtained without causing any safety problem on human being. wherein A represents H or OH group; B represents H or methyl group; and n represents an integer of from 0 to 2.

公开(公告)号：US06759557B2

公开(公告)日：2004-07-06

申请号：US10164702

申请日：2002-06-10

申请人： Hiroyuki Matsuda ,  Hiroyasu Kumamoto ,  Eiko Tamai ,  Misao Yagi ,  Kenichi Yamamoto ,  Toshimitsu Hagiwara ,  Shinya Watanabe

发明人： Hiroyuki Matsuda ,  Hiroyasu Kumamoto ,  Eiko Tamai ,  Misao Yagi ,  Kenichi Yamamoto ,  Toshimitsu Hagiwara ,  Shinya Watanabe

IPC分类号： C07C49105

CPC分类号： C07C49/703 ,  A61K8/35 ,  A61K2800/782 ,  A61Q19/02 ,  C07C45/45 ,  C07C45/62 ,  C07C49/385 ,  C07C49/487 ,  C07C49/587

摘要： A melanin synthesis inhibitor composition containing at least one macrocyclic compound represented by Formula (1) wherein X is a group selected among the groups consisting of C═O; CH—OH and O═C—CHOH; R being a chain hydrocarbon having 13 to 24 carbon atoms, R forms a ring with X and may be saturated or contain 1 to 3 unsaturated bonds and may be substituted by a lower alkyl group of 1 to 3 carbon atoms.

摘要翻译： 含有至少一种由式（1）表示的大环化合物的黑色素合成抑制剂组合物，其中X是选自由C = O组成的组中的基团; CH-OH和O = C-CHOH; R是具有13-24个碳原子的链烃，R与X形成具有X的环并且可以是饱和的或含有1-3个不饱和键，并且可以被1至3个碳原子的低级烷基取代。

公开(公告)号：US07923585B2

公开(公告)日：2011-04-12

申请号：US11628086

申请日：2004-05-31

申请人： Kenya Ishida ,  Takashi Aida ,  Hiroyuki Matsuda ,  Fumihiro Yanaka

发明人： Kenya Ishida ,  Takashi Aida ,  Hiroyuki Matsuda ,  Fumihiro Yanaka

IPC分类号： C07C43/00 ,  A61K9/00 ,  A61K8/02

CPC分类号： A61K8/39 ,  A61K2800/244 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q19/00 ,  A61Q19/10 ,  C07C43/196 ,  C07C2601/14

摘要： The invention relates to innovative menthol derivatives which are represented by the general formula (I) below and are excellent in a cooling effect and cool retaining effect, cooling agent compositions comprising the menthol derivatives, and sensory stimulation agent compositions containing the cooling agent compositions, as well as fragrance compositions, beverage or food products, cosmetic products, toiletry products, bathing agents, and pharmaceutical products containing the cooling agent compositions or sensory stimulation agent compositions. (general formula (I)) wherein R represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an acyl group having 1 to 5 carbon atoms; R and R independently represent an alkylene group having 2 to 5 carbon atoms and optionally having a substituent; double dotted line represents a single bond or a double bond; and n is an integer of 1 to 3.

摘要翻译： 本发明涉及由以下通式（I）表示并具有优异的冷却效果和冷保留效果的创新薄荷醇衍生物，包含薄荷醇衍生物的冷却剂组合物和含有冷却剂组合物的感觉刺激剂组合物，作为 以及香料组合物，饮料或食品，化妆品，化妆品，洗浴剂和含有冷却剂组合物或感觉刺激剂组合物的药物制品。 （通式（I））其中R 1表示氢原子，具有1至4个碳原子的烷基或具有1至5个碳原子的酰基; R 2和R 3独立地表示具有2至5个碳原子并且任选具有取代基的亚烷基; 双点划线表示单键或双键; n为1〜3的整数。

公开(公告)号：US06440400B1

公开(公告)日：2002-08-27

申请号：US09601508

申请日：2000-08-02

申请人： Takashi Aida ,  Hiroyuki Matsuda ,  Kenya Ishida ,  Tetsuro Yamasaki ,  Eiko Tamai ,  Kazuhiko Tokoro

发明人： Takashi Aida ,  Hiroyuki Matsuda ,  Kenya Ishida ,  Tetsuro Yamasaki ,  Eiko Tamai ,  Kazuhiko Tokoro

IPC分类号： A61K742

CPC分类号： C11B9/0034 ,  A61K8/34 ,  A61K8/35 ,  A61Q13/00 ,  A61Q19/02 ,  C07C31/1355 ,  C07C33/14 ,  C07C49/11 ,  C07C49/15 ,  C07C403/08 ,  C07C403/16 ,  C07C2601/14

摘要： The present invention is a trimethylcyclohexane derivative represented by Formula (1): wherein A represents C═O or CH—OH, n represents 2, R1 represents hydrogen or a methyl group, R2 represents a straight or branched, saturated or unsaturated hydrocarbon group having 3 to 10 carbon atoms, and a dotted line represents a saturated or unsaturated carbon-carbon bond, a melanin production inhibitor and a fragrance fixative comprising one or more of the trimethylcyclohexane derivatives, and a dermal formulation comprising one or more of the melanin production inhibitors and/or fragrance fixatives.

摘要翻译： 本发明是由式（1）表示的三甲基环己烷衍生物：其中A表示C = O或CH-OH，n表示2，R1表示氢或甲基，R2表示直链或支链，饱和或不饱和的烃基， 3至10个碳原子，虚线表示饱和或不饱和碳 - 碳键，黑色素产生抑制剂和包含一种或多种三甲基环己烷衍生物的香料固定剂和包含一种或多种黑色素产生抑制剂的皮肤制剂 和/或香料固定剂。

公开(公告)号：US20070225378A1

公开(公告)日：2007-09-27

申请号：US11628086

申请日：2004-05-31

申请人： Kenya Ishida ,  Takashi Aida ,  Hiroyuki Matsuda ,  Fumihiro Yanaka

发明人： Kenya Ishida ,  Takashi Aida ,  Hiroyuki Matsuda ,  Fumihiro Yanaka

IPC分类号： C07C43/196 ,  C07C43/184

CPC分类号： A61K8/39 ,  A61K2800/244 ,  A61Q5/02 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q19/00 ,  A61Q19/10 ,  C07C43/196 ,  C07C2601/14

摘要： The invention relates to innovative menthol derivatives which are represented by the general formula (I) below and are excellent in a cooling effect and cool retaining effect, cooling agent compositions comprising the menthol derivatives, and sensory stimulation agent compositions containing the cooling agent compositions, as well as fragrance compositions, beverage or food products, cosmetic products, toiletry products, bathing agents, and pharmaceutical products containing the cooling agent compositions or sensory stimulation agent compositions. (general formula (I)) wherein R represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an acyl group having 1 to 5 carbon atoms; R and R independently represent an alkylene group having 2 to 5 carbon atoms and optionally having a substituent; double dotted line represents a single bond or a double bond; and n is an integer of 1 to 3.

摘要翻译： 本发明涉及由以下通式（I）表示并具有优异的冷却效果和冷保持效果的创新薄荷醇衍生物，包含薄荷醇衍生物的冷却剂组合物和含有冷却剂组合物的感觉刺激剂组合物，如 以及香料组合物，饮料或食品，化妆品，化妆品，洗浴剂和含有冷却剂组合物或感觉刺激剂组合物的药物制品。 （通式（I））其中R 1表示氢原子，具有1至4个碳原子的烷基或具有1至5个碳原子的酰基; R 2和R 3独立地表示具有2至5个碳原子并且任选具有取代基的亚烷基; 双点划线表示单键或双键; n为1〜3的整数。

公开(公告)号：US07132391B2

公开(公告)日：2006-11-07

申请号：US10193024

申请日：2002-07-10

申请人： Takashi Aida ,  Andrew T. Lupo ,  Hiroyuki Matsuda

发明人： Takashi Aida ,  Andrew T. Lupo ,  Hiroyuki Matsuda

IPC分类号： A61Q13/00

CPC分类号： C07C43/13 ,  C07C43/178 ,  C11B9/0015 ,  C11D3/50 ,  D06L4/21 ,  D06L4/23 ,  D06L4/26

摘要： An alkyl gycol ether having the following formula wherein R is a C1–C7 saturated, unsaturated, straight-chain or branched, acyclic or cyclic alkyl group, is useful as a fragrance material in perfumes, cosmetics, consumer products, and the like. When R is a saturated, straight-chain or branched, acyclic or cyclic alkyl group, these compounds are especially stable when used as fragrance materials in bleach containing products.

摘要翻译： 具有下式的烷基gycol醚其中R是饱和的，不饱和的，直链的或支链的，无环的或环状的烷基，其可用作 香水，化妆品，消费品等中的香料。 当R是饱和，直链或支链，无环或环状烷基时，当用作含漂白剂的产品中的香料时，这些化合物特别稳定。

公开(公告)号：US06489273B1

公开(公告)日：2002-12-03

申请号：US09723401

申请日：2000-11-28

申请人： Takashi Aida ,  Hiroyuki Matsuda ,  Tetsuro Yamasaki

发明人： Takashi Aida ,  Hiroyuki Matsuda ,  Tetsuro Yamasaki

IPC分类号： A61K746

CPC分类号： C07C69/003 ,  C07C31/1355 ,  C07C2601/14 ,  C11D3/50

摘要： A fragrance, having a 2-cyclohexyl-1,1-dimethyl ethanol derivative represented by formula (1), wherein R represents a hydrogen atom or an acetyl group, Me represents a methyl group and n represents an integer from 0 to 3, provides a very pleasing scent, has excellent stability in a product, and can be mixed well with other fragrances.

摘要翻译： 一种具有式（1）所示的2-环己基-1,1-二甲基乙醇衍生物的芳香剂，其中R表示氢原子或乙酰基，Me表示甲基，n表示0〜3的整数， 一种非常美味的香味，在产品中具有极好的稳定性，可与其他香料混合。

公开(公告)号：US20150224579A1

公开(公告)日：2015-08-13

申请号：US13882723

申请日：2012-12-08

申请人： Hiroyuki Matsuda ,  Gorou Arahi ,  Hidenori Ando

发明人： Hiroyuki Matsuda ,  Gorou Arahi ,  Hidenori Ando

IPC分类号： B23B5/36 ,  C03B11/06

CPC分类号： B23B5/36 ,  B23B1/00 ,  B29C33/303 ,  B29L2011/0016 ,  C03B11/06 ,  C03B11/082 ,  C03B2215/06 ,  C03B2215/414 ,  Y10T82/10

摘要： A metal mold manufacturing method is provided, which is capable of forming a metal mold having a plurality of transfer surfaces with positions of optical axes being different by a lathe at high accuracy. An n-th (n is an integer of 1 to 4) side surface SDn of a material 1 of the metal mold abuts against an X-axis directional reference plane 2b of a jig 2, an (n+1)th side surface (but n=1 when n is 4) of a material 1′ of the metal mold abuts against a Y-axis directional reference plane 2c of the jig 2, and the material 1 of the metal mold is thus fixed to the jig 2. Subsequently, the n-th transfer surface is formed by cutting the material 1′ of the metal mold while rotating the jig 2 and the material 1 of the metal mold together by a lathe. Thereafter, the steps are repeated in a way that raises n by one.

摘要翻译： 提供了一种金属模具制造方法，其能够以高精度形成具有多个转轴表面的金属模具，其中光轴的位置由车床不同。 金属模的材料1的第n（n为1〜4的整数）侧面SDn与夹具2的X轴方向基准面2b抵接，第（n + 1）侧面 但n = 1时，n = 1，金属模的材料1'与夹具2的Y轴方向基准面2c抵接，金属模的材料1固定在夹具2上。随后 通过在车床上将金属模具2和金属模具的材料1一起旋转的同时，通过切割金属模具的材料1'来形成第n个转印面。 此后，以将n提高1的方式重复这些步骤。

公开(公告)号：US20140055860A1

公开(公告)日：2014-02-27

申请号：US13988483

申请日：2012-10-09

申请人： Tomoyuki Morimoto ,  Takashi Sannokyou ,  Hiroshi Nagoya ,  Hiroumi Tanigawa ,  Hiroyuki Matsuda ,  Toshiyuki Imai ,  Sadaharu Honda ,  Takahiro Mizukane ,  Kojiro Takatori ,  Shuhei Ashida

发明人： Tomoyuki Morimoto ,  Takashi Sannokyou ,  Hiroshi Nagoya ,  Hiroumi Tanigawa ,  Hiroyuki Matsuda ,  Toshiyuki Imai ,  Sadaharu Honda ,  Takahiro Mizukane ,  Kojiro Takatori ,  Shuhei Ashida

IPC分类号： G02B13/00 ,  G02B7/02

CPC分类号： G02B13/0015 ,  B29D11/00298 ,  B29D11/00403 ,  G02B3/0031 ,  G02B3/0062 ,  G02B7/02 ,  G02B7/021 ,  G02B13/003 ,  G02B13/0085 ,  Y10T29/49998 ,  Y10T156/1052

摘要： To provide a lens unit producing method capable for positioning a lens array with high precision over a long period of time, a lens array, and a lens unit. When the first flat surfaces LA1f come in contact with the respective tapered surfaces HLD1, the glass lens array LA1 cannot rotate more than that for the holder HLD. Meanwhile, since the tapered surfaces HLD1 are regulated by the respective opposite first flat surface LA1f, the glass lens array LA1 cannot move more than that relatively to the holder HLD. That is, by holding the glass lens array LA1 with the holder HLD, the glass lens array LA1 can be positioned with high precision for the holder HLD.

摘要翻译： 为了提供能够长时间高精度地定位透镜阵列的透镜单元制造方法，透镜阵列和透镜单元。 当第一平面LA1f与各个锥面HLD1接触时，玻璃透镜阵列LA1不能比保持器HLD旋转更多。 同时，由于锥形表面HLD1被相应的相对的第一平坦表面LA1f调节，所以玻璃透镜阵列LA1不能相对于保持器HLD移动。 也就是说，通过用保持器HLD保持玻璃透镜阵列LA1，玻璃透镜阵列LA1可以高精度地定位于保持器HLD。