公开(公告)号：US20090317813A1

公开(公告)日：2009-12-24

申请号：US12310331

申请日：2007-03-30

申请人： Takashi Imai ,  Mayumi Iwakawa ,  Hitoshi Shibuya ,  Masahiko Miura ,  Ryoichi Yoshimura ,  Hiroshi Watanabe

发明人： Takashi Imai ,  Mayumi Iwakawa ,  Hitoshi Shibuya ,  Masahiko Miura ,  Ryoichi Yoshimura ,  Hiroshi Watanabe

IPC分类号： C12Q1/68

CPC分类号： G01N33/57407 ,  C12Q1/6886 ,  C12Q2600/118 ,  G01N2333/705 ,  G01N2333/71

摘要： A method for objectively predicting possibility of metastasis to a cervical lymph node in an early stage for an individual case diagnosed as an oral cavity cancer, and a diagnosis kit to be used in the prediction are provided. The method includes a step of assaying expression amounts of metastasis prediction genes in which the expression amounts are changed between a metastasis group and a non-metastasis group, with respect to a sample collected from a primary legion of the oral cavity cancer. Further, the method includes a step of predicting the possibility of the metastasis by comparing the expression amounts of the metastasis gene group with the expression amounts of the metastasis prediction genes in a metastasis group and/or a non-metastasis group. Herein, the metastasis prediction gene group includes two genes MSR1 (NM_138716.1) and RET (M31213.1).

摘要翻译： 提供了用于客观预测诊断为口腔癌的个别病例的早期颈部淋巴结转移可能性的方法，以及用于预测的诊断试剂盒。 该方法包括相对于从口腔癌的主要团队收集的样品，测定转移组和非转移组之间的表达量发生变化的转移预测基因的表达量的步骤。 此外，该方法包括通过将转移基因组的表达量与转移组和/或非转移组中的转移预测基因的表达量进行比较来预测转移的可能性的步骤。 这里，转移预测基因组包括两个基因MSR1（NM_138716.1）和RET（M31213.1）。

公开(公告)号：US08129122B2

公开(公告)日：2012-03-06

申请号：US12310331

申请日：2007-03-30

申请人： Takashi Imai ,  Mayumi Iwakawa ,  Hitoshi Shibuya ,  Masahiko Miura ,  Ryoichi Yoshimura ,  Hiroshi Watanabe

发明人： Takashi Imai ,  Mayumi Iwakawa ,  Hitoshi Shibuya ,  Masahiko Miura ,  Ryoichi Yoshimura ,  Hiroshi Watanabe

IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12N15/11 ,  C12N15/12

CPC分类号： G01N33/57407 ,  C12Q1/6886 ,  C12Q2600/118 ,  G01N2333/705 ,  G01N2333/71

摘要： A method for objectively predicting possibility of metastasis to a cervical lymph node in an early stage for an individual case diagnosed as an oral cavity cancer, and a diagnosis kit to be used in the prediction are provided. The method includes a step of assaying expression amounts of metastasis prediction genes in which the expression amounts are changed between a metastasis group and a non-metastasis group, with respect to a sample collected from a primary legion of the oral cavity cancer. Further, the method includes a step of predicting the possibility of the metastasis by comparing the expression amounts of the metastasis gene group with the expression amounts of the metastasis prediction genes in a metastasis group and/or a non-metastasis group. Herein, the metastasis prediction gene group includes two genes MSR1 (NM_138716.1) and RET (M31213.1).

摘要翻译： 提供了用于客观预测诊断为口腔癌的个别病例的早期颈部淋巴结转移可能性的方法，以及用于预测的诊断试剂盒。 该方法包括相对于从口腔癌的主要团队收集的样品，测定转移组和非转移组之间的表达量发生变化的转移预测基因的表达量的步骤。 此外，该方法包括通过将转移基因组的表达量与转移组和/或非转移组中的转移预测基因的表达量进行比较来预测转移的可能性的步骤。 这里，转移预测基因组包括两个基因MSR1（NM_138716.1）和RET（M31213.1）。

公开(公告)号：US07226354B2

公开(公告)日：2007-06-05

申请号：US10416425

申请日：2002-05-29

申请人： Tomoyuki Kawano ,  Toshihiro Higashi ,  Hiroaki Koba ,  Ichiro Ikenaga ,  Kazuya Tokunaga ,  Satoru Yoshimitsu ,  Hitoshi Shibuya

发明人： Tomoyuki Kawano ,  Toshihiro Higashi ,  Hiroaki Koba ,  Ichiro Ikenaga ,  Kazuya Tokunaga ,  Satoru Yoshimitsu ,  Hitoshi Shibuya

IPC分类号： F24F7/00

CPC分类号： A47B96/00 ,  A47B81/00 ,  A47F3/001 ,  F24F7/065

摘要： A cabinet wherein air sucked from an inlet opening 4d of a shelf board combined inlet duct 4 by drive of an air purification unit 3 is passed through the shelf board combined inlet duct 4 and introduced into the inside of a case 3a, and by a dust collection filter 32 and an odor eliminating means 33. Air forced into the shelf board combined outlet duct 5 through the air duct 10 is exhausted through an outlet opening 5d of the shelf board combined outlet duct 5, and air curtain is formed along the opening of the storage section 11 of a cabinet 1. Therefore, air in the storage section 11 of the cabinet 1 is circulated and purified, while getting caught in a circulating airflow including the air curtain.

摘要翻译： 通过空气净化单元3的驱动从搁板组合入口管道4的入口开口4d吸入的空气通过搁板组合入口导管4并被引入到壳体3a的内部，并通过 集尘过滤器32和除臭装置33。 通过空气管道10被迫进入搁板组合出口管道5的空气通过搁板组合出口管道5的出口5d排出，并且沿机柜1的存储部分11的开口形成气幕。 因此，机壳1的收纳部11的空气在被包围气帘的循环空气流中被循环净化。

公开(公告)号：US20070200053A1

公开(公告)日：2007-08-30

申请号：US11701525

申请日：2007-02-01

申请人： Takumi Nomura ,  Hitoshi Shibuya

发明人： Takumi Nomura ,  Hitoshi Shibuya

IPC分类号： H01L33/00

CPC分类号： H01L27/14618 ,  H01L2224/48091 ,  H01L2224/73265 ,  H01L2924/00011 ,  H01L2924/00014 ,  H01L2924/01005

摘要： An image pickup apparatus may include a wiring board; a frame member having a framework-like shape and disposed on the wiring board, an image pickup element disposed on the inner side of the frame member on the wiring board, and a transparent cover disposed on the frame member. The wiring board and the frame member may be attached to each other by thermosetting adhesive. The frame member may be made of a material which has a coefficient of thermal expansion lower than that of the wiring board and has a rigidity higher than that of the wiring board.

摘要翻译： 图像拾取装置可以包括布线​​板; 具有框架状的框架构件，布置在所述布线板上，设置在所述框架构件的所述布线板的内侧的图像拾取元件以及设置在所述框架构件上的透明盖。 布线板和框架构件可以通过热固性粘合剂彼此附接。 框架构件可以由热膨胀系数低于布线板的热膨胀系数的材料制成，并且具有比布线板高的刚性。