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公开(公告)号：US20130079729A1
公开(公告)日：2013-03-28
申请号：US13638473
申请日：2011-03-02
IPC分类号： A61M5/315
CPC分类号： A61M5/31511 , A61M5/3129 , A61M5/3135 , A61M5/3137
摘要： A needle does not come off even if a high back pressure occurs at the skin upper section. Thus, the drug leakage from the skin can be prevented. A drug administration device 1 includes a tubular section 2 having a fluid chamber 7 capable of accommodating a drug and a discharge section 22, a pusher member 3 moving within the tubular section 2, a grip section 4, and a connection section 5. The pusher member 3 includes a rod-shape plunger 31 and a gasket 32. The grip section 4 is disposed along the outer periphery of the tubular section 2 and kept away from the tubular section 2, and the connection section 5 is formed between the tubular section 2 and the grip section 4.
摘要翻译： 即使皮肤上部发生高背压，针头也不会脱落。 因此，可以防止从皮肤泄漏的药物。 药剂管理装置1包括具有能够容纳药物的流体室7和排出部22的管状部2，在管状部2内移动的推动部3，夹持部4以及连接部5。 构件3包括棒状柱塞31和垫圈32.把手部分4沿着管状部分2的外周设置并远离管状部分2，并且连接部分5形成在管状部分2之间 和握持部4。
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公开(公告)号：US09302051B2
公开(公告)日：2016-04-05
申请号：US13638473
申请日：2011-03-02
CPC分类号： A61M5/31511 , A61M5/3129 , A61M5/3135 , A61M5/3137
摘要： A needle does not come off even if a high back pressure occurs at the skin upper section. Thus, the drug leakage from the skin can be prevented. A drug administration device 1 includes a tubular section 2 having a fluid chamber 7 capable of accommodating a drug and a discharge section 22, a pusher member 3 moving within the tubular section 2, a grip section 4, and a connection section 5. The pusher member 3 includes a rod-shape plunger 31 and a gasket 32. The grip section 4 is disposed along the outer periphery of the tubular section 2 and kept away from the tubular section 2, and the connection section 5 is formed between the tubular section 2 and the grip section 4.
摘要翻译： 即使皮肤上部发生高背压，针头也不会脱落。 因此，可以防止从皮肤泄漏的药物。 药剂管理装置1包括具有能够容纳药物的流体室7和排出部22的管状部2，在管状部2内移动的推动部3，夹持部4以及连接部5。 构件3包括棒状柱塞31和垫圈32.把手部分4沿着管状部分2的外周设置并远离管状部分2，并且连接部分5形成在管状部分2之间 和握持部4。
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公开(公告)号：US08663163B2
公开(公告)日：2014-03-04
申请号：US13062406
申请日：2009-09-24
CPC分类号： A61M5/46 , A61M5/3134 , A61M5/3287 , A61M5/425
摘要： A needle tip of a needle tube stuck in the skin is caused to be reliably positioned in the skin upper layer part and the injected drug is caused not to leak to the outside of the body. An injection needle is provided with a needle tube having a needle tip, a hub that holds the needle tube and an adjustment unit provided around the needle tube and having a needle-protruding surface through which the needle tip of the needle tube protrudes. The needle-protruding surface of the adjustment unit is formed such that the distance S from the circumferential edge to the circumferential surface of the needle tube is in the range of 0.3-1.4 mm.
摘要翻译： 粘贴在皮肤上的针管的针尖被可靠地定位在皮肤上层部分，并且使注射的药物不会泄漏到身体的外部。 注射针设置有具有针尖的针管，保持针管的轮毂和设置在针管周围的调节单元，并具有针管的针尖突出的针突出面。 调整单元的针突出面形成为从针筒的周缘到周面的距离S在0.3〜1.4mm的范围内。
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公开(公告)号：US20110275994A1
公开(公告)日：2011-11-10
申请号：US13145427
申请日：2010-01-29
申请人： Yoichiro Iwase , Kazunori Koiwai , Tetsuo Tanaka , Sayaka Oomori
发明人： Yoichiro Iwase , Kazunori Koiwai , Tetsuo Tanaka , Sayaka Oomori
IPC分类号： A61M5/46
摘要： To securely position a needle tip and a blade face of a needle tube inserted into the skin in a predetermined site of a living body, such as the upper layer of skin, an injection needle assembly includes a needle tube having a needle tip capable of puncturing a living body, a hub holding the needle tube, a stabilizer, and a guide portion. The stabilizer is formed in a tubular shape surrounding the circumference of the needle tube, and an end face is pressed against the skin, and thereby a raised portion of the skin is formed in a tube hole. The guide portion is arranged on the stabilizer, and is adapted to recognize a press-in distance y of the stabilizer to the skin.
摘要翻译： 为了将诸如皮肤上层的生物体的预定位置中插入皮肤的针管的针尖和刀片面牢固地定位，则注射针组件包括具有能够穿刺的针尖的针管 活体，保持针管的轮毂，稳定器和引导部。 稳定器形成为围绕针管的圆周的管状，并且将端面压在皮肤上，由此将皮肤的凸起部形成在管孔中。 引导部分布置在稳定器上，并且适于识别稳定器到皮肤的压入距离y。
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公开(公告)号：US08622963B2
公开(公告)日：2014-01-07
申请号：US13145427
申请日：2010-01-29
申请人： Yoichiro Iwase , Kazunori Koiwai , Tetsuo Tanaka , Sayaka Oomori
发明人： Yoichiro Iwase , Kazunori Koiwai , Tetsuo Tanaka , Sayaka Oomori
IPC分类号： A61M5/00
摘要： To securely position a needle tip and a blade face of a needle tube inserted into the skin in a predetermined site of a living body, such as the upper layer of skin, an injection needle assembly includes a needle tube having a needle tip capable of puncturing a living body, a hub holding the needle tube, a stabilizer, and a guide portion. The stabilizer is formed in a tubular shape surrounding the circumference of the needle tube, and an end face is pressed against the skin, and thereby a raised portion of the skin is formed in a tube hole. The guide portion is arranged on the stabilizer, and is adapted to recognize a press-in distance y of the stabilizer to the skin.
摘要翻译： 为了将诸如皮肤上层的生物体的预定位置中插入皮肤的针管的针尖和刀片面牢固地定位，则注射针组件包括具有能够穿刺的针尖的针管 活体，保持针管的轮毂，稳定器和引导部。 稳定器形成为围绕针管的圆周的管状，并且将端面压在皮肤上，由此将皮肤的凸起部形成在管孔中。 引导部分布置在稳定器上，并且适于识别稳定器到皮肤的压入距离y。
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公开(公告)号：US20120046615A1
公开(公告)日：2012-02-23
申请号：US13262082
申请日：2010-03-05
申请人： Kazunori Koiwai , Yoichiro Iwase
发明人： Kazunori Koiwai , Yoichiro Iwase
IPC分类号： A61M5/32
CPC分类号： A61M5/3243 , A61M5/3271 , A61M5/3287 , A61M5/46 , A61M2005/3247
摘要： An injection needle assembly includes a needle tube 2 having a needle tip capable of being stuck into a living body, a hub 3 holding the needle tube 2, a stabilization unit 6 arranged so as to cover the circumference of the needle tube 2 in a condition that the needle tip of the needle tube 2 protrudes and having an end face 6c that contacts the skin when causing the needle tube 2 to be stuck into the living body, and housing units 7 and 8. The housing units 7 and 8 are movable along the axial direction of the needle tube 2 from the first position where the needle tip of the needle tube 2 is exposed to the second position where the needle tip of the needle tube 2 is housed.
摘要翻译： 注射针组件包括具有能够插入生物体中的针尖的针管2，保持针管2的轮毂3，布置成以条件覆盖针管2的周围的稳定单元6 针管2的针尖突出并且具有在使针管2卡在生物体中时与皮肤接触的端面6c以及容纳单元7和8.壳体单元7和8可沿着 针管2从针管2的针尖的第一位置的轴向朝向针管2的针尖的第二位置露出。
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公开(公告)号：US20110166520A1
公开(公告)日：2011-07-07
申请号：US13062406
申请日：2009-09-24
CPC分类号： A61M5/46 , A61M5/3134 , A61M5/3287 , A61M5/425
摘要： A needle tip of a needle tube stuck in the skin is caused to be reliably positioned in the skin upper layer part and the injected drug is caused not to leak to the outside of the body.An injection needle 1 is provided with a needle tube 2 of 26-33 G having a needle tip, a hub 3 that holds the needle tube 2, and an adjustment unit 4 provided around the needle tube 2 and having a needle-protruding surface 4b through which the needle tip of the needle tube 2 protrudes. And, the needle-protruding surface 4b of the adjustment unit 4 is formed such that the distance S from the circumferential edge to the circumferential surface of the needle tube 2 is in the range of 0.3-1.4 mm.
摘要翻译： 粘贴在皮肤上的针管的针尖被可靠地定位在皮肤上层部分，并且使注射的药物不会泄漏到身体的外部。 注射针1设置有具有针尖的26-33G针管2，保持针管2的轮毂3和设置在针管2周围并具有针突出面4b的调节单元4 针管2的针尖突出。 并且，调整单元4的针突出面4b形成为从针筒2的周缘到周面的距离S在0.3〜1.4mm的范围内。
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公开(公告)号：US07297475B2
公开(公告)日：2007-11-20
申请号：US10840600
申请日：2004-05-07
申请人： Kazunori Koiwai , Tetsuo Tanaka
发明人： Kazunori Koiwai , Tetsuo Tanaka
CPC分类号： A61M31/00 , A61K48/00 , A61M25/10 , A61M2025/1052
摘要： A medicament injection kit, for use in occluding a renal artery and a renal vein in a kidney and injecting a therapeutic medicament into the kidney so as to pressurize the kidney, includes: an artery catheter which includes a first balloon capable of occluding the renal artery; a vein catheter which includes a second balloon capable of occluding the renal vein; a syringe for injecting the therapeutic medicament, the syringe being capable of being connected to at least one of the artery catheter and the vein catheter; and a syringe for pressurizing the inside of the kidney by injecting a liquid, the syringe being capable of being connected to at least one of the artery catheter and the vein catheter.
摘要翻译： 一种药物注射试剂盒，用于阻断肾脏中的肾动脉和肾静脉，并将治疗药物注入肾脏以加压肾脏，包括：动脉导管，其包括能够闭塞肾动脉的第一气囊 ; 静脉导管，其包括能够闭塞肾静脉的第二球囊; 用于注射治疗药物的注射器，所述注射器能够连接到动脉导管和静脉导管中的至少一个; 以及注射器，其通过注射液体来对肾脏的内部加压，所述注射器能够连接到动脉导管和静脉导管中的至少一个。
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公开(公告)号：US06228391B1
公开(公告)日：2001-05-08
申请号：US09202193
申请日：1998-12-10
IPC分类号： C07C25714
CPC分类号： C07C257/18 , A61K9/1272 , C07C257/14 , C07C335/32 , C07C335/36
摘要： Novel amidine derivatives of the formula (1); and drug carriers such as liposomes or emulsions comprising the derivatives, which can enclose genetic materials or drugs and transfer them to cells or affected sites efficiently and safely, wherein A is an aromatic ring, R1 and R2 are the same or different and independently represent an alkyl group having any one of 10 to 25 carbon atoms, and an alkenyl group having any one of 10 to 25 carbon atoms, X and Y are the same or different and independently represent —O—, —S—, —COO—, —OCO—, —CONH—, or —NHCO—, m is 0 or 1, and n is 0 or a natural number of 1 to 6.
摘要翻译： 式（1）的新型脒衍生物; 和药物载体如脂质体或包含衍生物的乳剂，其可以包裹遗传材料或药物并且有效和安全地将它们转移到细胞或受影响的位点，其中A是芳环，R 1和R 2相同或不同并且独立地表示 具有10至25个碳原子的任何一个的烷基和具有10至25个碳原子的任何一个的烯基可以相同或不同并且独立地表示-O - ， - S - ， - COO - ， - OCO-，-CONH-或-NHCO-，m为0或1，n为0或自然数为1至6。
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