公开(公告)号：US10208077B1

公开(公告)日：2019-02-19

申请号：US16101412

申请日：2018-08-11

申请人： Taotao Qiang ,  Yunying Song ,  Longfang Ren ,  Xuechuang Wang ,  Chengyuan Liang ,  Lei Tian ,  Xinke Ju ,  Han Li ,  Qianqian Zhao

发明人： Taotao Qiang ,  Yunying Song ,  Longfang Ren ,  Xuechuang Wang ,  Chengyuan Liang ,  Lei Tian ,  Xinke Ju ,  Han Li ,  Qianqian Zhao

IPC分类号： C07H17/075

摘要： A compound having the formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US10208078B1

公开(公告)日：2019-02-19

申请号：US16101414

申请日：2018-08-11

申请人： Chengyuan Liang ,  Minyi Jia ,  Songsong Ruan ,  Jie Li ,  Lei Tian ,  Xinke Ju ,  Han Li ,  Qianqian Zhao ,  Xuechuang Wang

发明人： Chengyuan Liang ,  Minyi Jia ,  Songsong Ruan ,  Jie Li ,  Lei Tian ,  Xinke Ju ,  Han Li ,  Qianqian Zhao ,  Xuechuang Wang

IPC分类号： C07H17/075

摘要： A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US10815348B2

公开(公告)日：2020-10-27

申请号：US16027193

申请日：2018-07-03

申请人： Xuechuan Wang ,  Ouyang Yue ,  Xinhua Liu ,  Taotao Qiang ,  Longfang Ren ,  Lei Tian ,  Minyi Jia ,  Xingke Ju ,  Chengyuan Liang

发明人： Xuechuan Wang ,  Ouyang Yue ,  Xinhua Liu ,  Taotao Qiang ,  Longfang Ren ,  Lei Tian ,  Minyi Jia ,  Xingke Ju ,  Chengyuan Liang

IPC分类号： C09H3/00 ,  C08J5/18 ,  B65D65/46 ,  C08L89/06 ,  G01N33/569

摘要： A method of preparing an aesculin sturgeon skin gelatin with antioxidant activity and Enterococcus faecalis detection ability includes: 1) mixing a sturgeon skin gelatin and distilled water in a ratio of 1:15-1:25 (w/v) at 50-70° C. and filtering to obtain a sturgeon skin gelatin solution; 2) adding aesculin and a glycerin solution to the sturgeon skin gelatin solution, stirring the resulted sturgeon skin gelatin solution at 30-50° C. for 30 minutes, and filtering; and 3) removing air bubbles from the sturgeon skin gelatin solution of step 2) under reduced pressure, placing the sturgeon skin gelatin solution on an acrylic glass, and drying the sturgeon skin gelatin solution at in a vented oven 25° C. and 45-55% relative humidity for 24 hours to obtain the aesculin sturgeon skin gelatin film.

公开(公告)号：US10343988B1

公开(公告)日：2019-07-09

申请号：US16359988

申请日：2019-03-20

申请人： Chengyuan Liang ,  Lei Tian ,  Danni Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao

发明人： Chengyuan Liang ,  Lei Tian ,  Danni Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao

IPC分类号： C07C323/56 ,  C07C319/20 ,  C09K15/14

摘要： A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US10336682B1

公开(公告)日：2019-07-02

申请号：US16359982

申请日：2019-03-20

申请人： Chengyuan Liang ,  Lei Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao ,  Gennian Mao ,  Nan Qin ,  Juan Xia ,  Zhenfeng Shi

发明人： Chengyuan Liang ,  Lei Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao ,  Gennian Mao ,  Nan Qin ,  Juan Xia ,  Zhenfeng Shi

IPC分类号： C07C69/757 ,  B01J31/02 ,  C07C67/08

摘要： A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US10766885B1

公开(公告)日：2020-09-08

申请号：US16871333

申请日：2020-05-11

申请人： Xingke Ju ,  Chengyuan Liang ,  Bin Tian ,  Yuzhi Liu ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

发明人： Xingke Ju ,  Chengyuan Liang ,  Bin Tian ,  Yuzhi Liu ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

IPC分类号： C07D407/14 ,  B01J31/02

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US10494377B1

公开(公告)日：2019-12-03

申请号：US16120403

申请日：2018-09-03

申请人： Bin Tian ,  Xingke Ju ,  Lei Tian ,  Jie Li ,  Songsong Ruan ,  Minyi Jia ,  Danni Tian ,  Han Li ,  Qianqian Zhao ,  Xuechuan Wang ,  Chengyuan Liang

发明人： Bin Tian ,  Xingke Ju ,  Lei Tian ,  Jie Li ,  Songsong Ruan ,  Minyi Jia ,  Danni Tian ,  Han Li ,  Qianqian Zhao ,  Xuechuan Wang ,  Chengyuan Liang

IPC分类号： C07D493/04

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US11306076B2

公开(公告)日：2022-04-19

申请号：US16871354

申请日：2020-05-11

申请人： Yonghong Tang ,  Huafeng Qi ,  Peiyu Zhou ,  Xingke Ju ,  Chengyuan Liang ,  Yuzhi Liu ,  Bin Tian ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

发明人： Yonghong Tang ,  Huafeng Qi ,  Peiyu Zhou ,  Xingke Ju ,  Chengyuan Liang ,  Yuzhi Liu ,  Bin Tian ,  Lei Tian ,  Gennian Mao ,  Limei Wang ,  Yuanyuan He ,  Yongbo Wang ,  Jingwen Xu ,  Dan Yang ,  Liang Qi ,  Wenbo Yao ,  Qianqian Zhao ,  Han Li

IPC分类号： C07D409/14 ,  B01J27/24

摘要： A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US11872202B2

公开(公告)日：2024-01-16

申请号：US17695741

申请日：2022-03-15

申请人： Chengyuan Liang ,  Xiuding Yang ,  Liang Xin ,  Juan Xia ,  Yuqing Zhao ,  Jie Zhang ,  Lei Tian ,  Jingyi Li ,  Shaojun Zhang ,  Qianqian Zhao

发明人： Chengyuan Liang ,  Xiuding Yang ,  Liang Xin ,  Juan Xia ,  Yuqing Zhao ,  Jie Zhang ,  Lei Tian ,  Jingyi Li ,  Shaojun Zhang ,  Qianqian Zhao

IPC分类号： A61K31/216 ,  A61P31/04

CPC分类号： A61K31/216 ,  A61P31/04

摘要： A pleuromutilin cinnamic acid ester compound with activities against antibiotic-resistant infections having the following formula (I)




R1, R2, R3, R4 and R5 are independently hydrogen, halogen, nitro, cyano, methoxy, trifluoromethyl, benzyloxy, aryl or dimethylamino.

公开(公告)号：US11186607B1

公开(公告)日：2021-11-30

申请号：US17134241

申请日：2020-12-25

申请人： Yonghong Tang ,  Bin Tian ,  Lei Tian ,  Yanjun Li ,  Qiao Zeng ,  Dan Yang ,  Liang Xin ,  Jingyi Li ,  Qianqian Zhao ,  Minghui Chang ,  Huafeng Qi ,  Zhuanmei Yuan ,  Wenbo Yao ,  Guaiping Qiao ,  Juan Li ,  Nan Hui ,  Han Li

发明人： Yonghong Tang ,  Bin Tian ,  Lei Tian ,  Yanjun Li ,  Qiao Zeng ,  Dan Yang ,  Liang Xin ,  Jingyi Li ,  Qianqian Zhao ,  Minghui Chang ,  Huafeng Qi ,  Zhuanmei Yuan ,  Wenbo Yao ,  Guaiping Qiao ,  Juan Li ,  Nan Hui ,  Han Li

IPC分类号： C07J9/00

摘要： A compound with antibacterial activity having the following formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.