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公开(公告)号:US20130149311A1
公开(公告)日:2013-06-13
申请号:US13696668
申请日:2011-05-06
IPC分类号: A61K39/395 , A61K31/454 , A61K38/10 , A61K31/7088
CPC分类号: A61K39/3955 , A61K31/454 , A61K31/7088 , A61K38/10 , A61K38/1709 , C12Q1/6876 , C12Q2600/136 , C12Q2600/158 , G01N33/74 , G01N2500/04
摘要: Methods, uses and kits for increasing the number of hematopoietic stem cells (HSCs) in a biological system, such as for increasing the number of HSCs in the bone marrow and/or blood of a subject, based on the modulation of growth factor independence 1b (Gfi1b), are disclosed.
摘要翻译: 基于生长因子独立性1b的调节,用于增加生物系统中造血干细胞(HSCs)数量的方法,用途和试剂盒,例如用于增加受试者的骨髓和/或血液中的HSC的数量 (Gfi1b)。