METHOD AND SYSTEM FOR REGIME-BASED PROCESS OPTIMIZATION OF INDUSTRIAL ASSETS

    公开(公告)号:US20220107630A1

    公开(公告)日:2022-04-07

    申请号:US17450243

    申请日:2021-10-07

    Abstract: This disclosure relates to a method and system for regime-based process optimization of various assets of industrial manufacturing and process plants or units. Operating regimes of assets are identified and a regime similarity score of each asset is computed from regime sequences of integrated industrial data and compared with a given threshold to identify regimes of operation. Operating regimes are matched with regimes of regime database and industrial assets and similar operating regimes are group together. Process optimization is carried out for each group of industrial assets to identify optimum settings in order to maximize output or minimize loss/cost considering process and equipment constraints. Anomalies are analyzed in the unmatched operating regimes and a diagnosis is carried out to identify the root cause for any detected anomalies. Remaining useful life of components in the assets with unmatched operating regimes is estimated to ensure component reliability and to prevent failure.

    DESIGN OF POLYMERIC CARRIERS FOR CONTROLLED RELEASE OF MOLECULES

    公开(公告)号:US20180225425A1

    公开(公告)日:2018-08-09

    申请号:US15889455

    申请日:2018-02-06

    CPC classification number: G16C20/10 G06F2217/16 G16C10/00 G16C20/30 G16C20/50

    Abstract: A system and method for design of polymeric carrier for controlled release of molecules is provided. The method includes receiving a plurality of input parameters of a polymeric carrier, a solvent, and molecules to be released from the polymeric carrier from a database and performing Molecular Dynamics (MD) simulations to estimate thermodynamic and transport properties of the polymeric carrier, the solvent and the molecules to be released using on one or more input parameters from the plurality of input parameters. Based on the estimated thermodynamic and transport properties, swelling and degradation kinetics of the polymeric carrier and release kinetics of the molecules to be released from the polymeric carrier is estimated and generating a proposed formulation based on difference between estimated released kinetics and the targeted release kinetics of the molecules.

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