公开(公告)号：US20220283561A1

公开(公告)日：2022-09-08

申请号：US17586995

申请日：2022-01-28

Applicant: Tata Consultancy Services Limited

Inventor： Venkata Sudheendra BUDDHIRAJU ,  Venkataramana RUNKANA ,  Vishnu Swaroopji MASAMPALLY ,  Anshul AGARWAL ,  Amey Ahsok KULKARNI ,  Keshari Nandan GUPTA ,  Navnath Manohar DEORE ,  Vinesh Balakrishnan YEZHUVATH ,  Anamika TIWARI ,  Anurag Singh RATHORE ,  Garima THAKUR ,  Nikita SAXENA ,  Shantanu BANERJEE

IPC: G05B19/05 ,  G06N5/00

Abstract: Process control of continuous production of biomolecules is a major challenge due to complex nature of processes and time scales of operations involved. Availability of key process variables in real-time is one of main requirements. This disclosure relates to a processor implemented method of controlling a continuous bioprocessing plant which includes at least one of: receiving, an input data associated with one or more equipments; generating, by a recipe builder, a sequence of unit operations to determine at least one job order based on the at least input data; obtaining, a control decision associated with a control parameter based on the at least one job order; communicating, via the middleware, the control decision associated with the control parameter to the PLC; and executing, by a control system of the PLC, the control decision on a unit equipment to control: (i) a continuous bioprocessing train, and (ii) an individual unit operation.