公开(公告)号：US20170290842A1

公开(公告)日：2017-10-12

申请号：US15626198

申请日：2017-06-19

Applicant: Tel HaShomer Medical Research Infrastructure and Services Ltd.

Inventor： Anat ACHIRON ,  Roi MASHIACH ,  Michael GUREVICH

IPC: A61K31/551

CPC classification number: A61K31/551 ,  C07D513/14 ,  C12Q1/6876 ,  C12Q2600/136 ,  C12Q2600/158 ,  Y02A50/414

Abstract: Provided are novel compounds which are capable of inhibiting an activity of RNA polymerase I, and uses thereof in treating diseases or disorders modulated by RNA polymerase I, preferably autoimmune diseases such as multiple sclerosis and proliferative diseases.