公开(公告)号：US20240238346A1

公开(公告)日：2024-07-18

申请号：US18577300

申请日：2022-07-08

Applicant: Temple University - of the Commonwealth System of Higher Education

Inventor： Sadia MOHSIN ,  Steven HOUSER ,  Hajime KUBO

IPC: A61K35/28 ,  A61K38/17 ,  A61P9/00

CPC classification number: A61K35/28 ,  A61K38/1754 ,  A61K38/1793 ,  A61P9/00

Abstract: Cell therapies and cell secretome compositions are utilized in the methods of treatment of cardiac injury. The compositions mediate myocardial homeostasis and cardiac wound healing process post-MI via the direct modulation of regulatory T cell (Treg) population dynamics and function.