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公开(公告)号：US20070192075A1
公开(公告)日：2007-08-16
申请号：US10590016
申请日：2005-02-14
申请人： Tetsuya Matsuda , Akira Amano , Hidetoshi Kotera , Kenta Hori , Jianyin Lu , Nobuaki Sarai , Satoshi Matsuoka , Akinori Noma , Takao Shimayoshi
发明人： Tetsuya Matsuda , Akira Amano , Hidetoshi Kotera , Kenta Hori , Jianyin Lu , Nobuaki Sarai , Satoshi Matsuoka , Akinori Noma , Takao Shimayoshi
CPC分类号： G16H50/50
摘要： With conventional simulation devices, the assumption was that only cells would be simulated, and thus the simulation devices had the problem that simulations on the level of tissue, organs, or individual organisms, which are collections of cells, were not possible. The present invention is an organism simulation device that is provided with two or more different simulator parts that calculate the behavior of organism structural elements, a data output part that visually outputs simulation results, and a simulation controller that controls the transfer of data between the two or more different simulator parts and the data output part based on simulation scenario information, which is information on the flow of data and the operation sequence. With this organism simulation device, an environment in which simulation of an organism can be performed more comprehensively and with higher precision can be provided with ease.
摘要翻译： 使用传统的模拟装置，假设只有细胞被模拟，因此仿真装置的问题在于，不可能对作为细胞集合的组织，器官或个体生物体的水平进行模拟。 本发明是一种生物模拟装置，其具有计算生物体结构要素的行为的两个或多个不同的模拟器部分，可视地输出模拟结果的数据输出部分，以及控制两者之间的数据传送的模拟控制器 或更多不同的模拟器部分和数据输出部分，其基于模拟情景信息，其是关于数据流和操作序列的信息。 利用这种有机体模拟装置，可以容易地提供可以更全面地和更高精度地进行生物体的模拟的环境。
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公开(公告)号：US07516017B2
公开(公告)日：2009-04-07
申请号：US11660746
申请日：2005-08-22
申请人： Akinori Noma , Nobuaki Sarai , Hiroyuki Kawano , Shohei Hido
发明人： Akinori Noma , Nobuaki Sarai , Hiroyuki Kawano , Shohei Hido
CPC分类号： G06K9/00496
摘要： It is an object of the invention to measure the change in action potential waveforms during administration of a drug by testing in cultured cells or in animals, and using this measurement to evaluate the influence of administration of the drug on biological parameters, thereby providing an approach to evaluating the effect on individual channels of a cell. The invention provides a biological parameter output apparatus that contains at least one piece of waveform information that includes at least one piece of biological parameter information, which is a set of a biological parameter identifier and a biological parameter value, and action potential waveform information, receives input of action potential waveform information, acquires at least one piece of biological parameter information based on the action potential waveform information, and outputs the at least one biological parameter information acquired. With this biological parameter output apparatus, it is possible to evaluate the effect on individual channels of a cell.
摘要翻译： 本发明的目的是通过在培养的细胞或动物中测试来测量药物给药期间动作电位波形的变化，并且使用该测量来评估药物施用对生物参数的影响，从而提供方法 评估细胞对个体通道的影响。 本发明提供一种生物参数输出装置，其包含至少一条波形信息，该波形信息包括作为生物参数标识符和生物参数值的集合的至少一条生物参数信息以及动作电位波形信息， 动作电位波形信息的输入，基于动作电位波形信息获取至少一条生物参数信息，并输出获取的至少一个生物参数信息。 利用该生物参数输出装置，可以评估对单元的各个通道的影响。
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公开(公告)号：US20070255504A1
公开(公告)日：2007-11-01
申请号：US11660746
申请日：2005-08-22
申请人： Akinori Noma , Nobuaki Sarai , Hiroyuki Kawano , Shohei Hido
发明人： Akinori Noma , Nobuaki Sarai , Hiroyuki Kawano , Shohei Hido
CPC分类号： G06K9/00496
摘要： It is an object of the invention to measure the change in action potential waveforms during administration of a drug by testing in cultured cells or in animals, and using this measurement to evaluate the influence of administration of the drug on biological parameters, thereby providing an approach to evaluating the effect on individual channels of a cell. The invention provides a biological parameter output apparatus that contains at least one piece of waveform information that includes at least one piece of biological parameter information, which is a set of a biological parameter identifier and a biological parameter value, and action potential waveform information, receives input of action potential waveform information, acquires at least one piece of biological parameter information based on the action potential waveform information, and outputs the at least one biological parameter information acquired. With this biological parameter output apparatus, it is possible to evaluate the effect on individual channels of a cell.
摘要翻译： 本发明的目的是通过在培养的细胞或动物中测试来测量药物给药期间动作电位波形的变化，并且使用该测量来评估药物施用对生物参数的影响，从而提供方法 评估细胞对个体通道的影响。 本发明提供一种生物参数输出装置，其包含至少一条波形信息，该波形信息包括作为生物参数标识符和生物参数值的集合的至少一条生物参数信息以及动作电位波形信息， 动作电位波形信息的输入，基于动作电位波形信息获取至少一条生物参数信息，并输出获取的至少一个生物参数信息。 利用该生物参数输出装置，可以评估对单元的各个通道的影响。
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