公开(公告)号：US12234516B2

公开(公告)日：2025-02-25

申请号：US17206895

申请日：2021-03-19

Applicant: The Board of Regents of the University of Texas System

Inventor： Min Soo Kim ,  James Brugarolas ,  Tae Hyun Hwang ,  Yang Xie

IPC: C12Q1/6886 ,  A61P35/00 ,  C12N15/52 ,  C40B40/08 ,  G01N33/50 ,  G16B25/00 ,  G16B25/10 ,  G16B25/20 ,  G16B30/00 ,  G16H50/20 ,  G16H50/30

Abstract: Described herein are methods and systems for identifying and/or treating subjects having cancer who are more likely to respond to treatment with an inhibitor of the transcription factor HIF-2α.