公开(公告)号：US20130131491A1

公开(公告)日：2013-05-23

申请号：US13680090

申请日：2012-11-18

申请人： The Board of Trustees of the Leland Stanford Junio

发明人： Phuoc Tho Tran ,  Pavan Bendapudi ,  Hen-Tzu Lin ,  David S. Paik ,  Dean W. Felsher

IPC分类号： A61B5/00 ,  A61B6/03 ,  A61B5/055

CPC分类号： A61B5/72 ,  A61B5/055 ,  A61B5/4848 ,  A61B5/7275 ,  A61B6/032 ,  A61B6/037 ,  A61B6/5217 ,  A61B8/5223 ,  G16H20/00 ,  G16H30/40 ,  G16H50/30 ,  G16H50/70

摘要： Tumor responses to a therapy can be predicted in a more objective and quantitative fashion allowing doctors to make earlier determinations of how well a tumor is responding to therapy. If a patient were not responding well, valuable time could be saved and the patient could be switched to a more efficacious therapy. Tumor response predictions to therapy are determined from a combination of (i) the tumor volumes over time, (ii) the cellular proliferation over time and (iii) the cellular apoptosis over time.

摘要翻译： 可以以更客观和定量的方式预测对治疗的肿瘤反应，使医生能够更早地确定肿瘤对治疗的反应程度。 如果患者的反应不好，宝贵的时间可以节省，患者可以切换到更有效的治疗方法。 从（i）随时间的肿瘤体积，（ii）随时间的细胞增殖和（iii）随时间的细胞凋亡的组合来确定治疗的肿瘤反应预测。