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公开(公告)号:US20210244659A1
公开(公告)日:2021-08-12
申请号:US17251605
申请日:2019-06-27
申请人: The Board of Trustees of the Leland Stanford Junior University , U.S. Government Represented by the Department of Veterans Affairs
发明人: David Myung , Sarah Hull , Sarah Heilshorn , Christopher Lindsay , Christopher Madl , Hyun Jong Lee
摘要: Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined gel structure in situ. Such gels can serve as cellular or acellular lamellar substitutes to reconstruct corneal stroma, facilitate matrix remodeling, and support multilayered re-epithelialization of wounded corneal stromal tissue, as well delivery vehicles for cells, biomolecules, and/or pharmaceutical agents to wound sites throughout the body.