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公开(公告)号：US10598750B2
公开(公告)日：2020-03-24
申请号：US15088353
申请日：2016-04-01
发明人： Matthew S. Rosen , Mathieu Sarracanie , Ouri Cohen
IPC分类号： G01R33/54 , G01R33/50 , G01R33/561 , G01R33/483
摘要： Provided is a system and method for performing a magnetic resonance fingerprinting imaging process. The process includes determining acquisition parameters including at least one of repetition time (TR) or flip angle (FA), selected to control one of a duration and a number of repetitions of for a pulse sequence that samples k-space in a Cartesian acquisition pattern by acquiring an echo train. The process also includes controlling a magnetic resonance imaging (MRI) system to perform the pulse sequence a plurality of times to acquire magnetic resonance fingerprinting (MRF) data corresponding to signals from the subject excited by the pulse sequence. The process also includes estimating quantitative tissue properties of the subject by comparing the MRF data to a database and reconstructing, from the MRF data, at least one image of the subject indicating the estimated quantitative tissue properties.
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2.发明授权公开(公告)号：US10466321B2
公开(公告)日：2019-11-05
申请号：US15294989
申请日：2016-10-17
发明人： Ouri Cohen
摘要： Systems and methods for acquiring magnetic resonance fingerprinting (MRF) data includes performing a schedule optimization that sequentially selects discrimination at each trajectory to yield an optimal trajectory and controlling a magnetic resonance imaging (MRI) system to perform a pulse sequence using the optimal trajectory to acquire MRF data. The process also includes estimating quantitative parameters of the subject using the MRF data by comparing the MRF data to a dictionary database and generating a map of quantitative parameters of the subject using the estimated quantitative parameters of the subject and the MRF data.
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3.发明申请公开(公告)号：US20170146623A1
公开(公告)日：2017-05-25
申请号：US15294977
申请日：2016-10-17
发明人： Ouri Cohen
IPC分类号： G01R33/44 , G01R33/56 , G01R33/563 , G01R33/48
CPC分类号： G01R33/4828 , G01R33/50 , G01R33/5602
摘要： Systems and methods for producing a quantitative parameter map using a magnetic resonance imaging (MRI) system includes providing magnetic resonance fingerprinting (MRF) data acquired with an MRI system from a subject. The MRF data represents a plurality of different signal evolutions acquired using different acquisition parameter settings. The method also includes providing a database comprising a plurality of sub-dictionaries, each sub-dictionary including a plurality of signal templates, sequentially comparing the MRF data to each of the sub-dictionaries to estimate quantitative parameters, and generating a quantitative parameter map of the subject using the estimate quantitative parameters.
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公开(公告)号：US10317501B2
公开(公告)日：2019-06-11
申请号：US15660221
申请日：2017-07-26
发明人： Mathieu Sarracanie , Matthew Rosen , Ouri Cohen , Lionel Broche
IPC分类号： G01R33/565 , G01R33/561 , G01R33/48 , G01R33/36
摘要： Systems and methods for magnetic resonance fingerprinting (“MRF”) using highly differentiated trajectories that optimize differentiation between magnetic resonance signal patterns as a function of relaxation time(s) and static magnetic field homogeneity are described. Using the optimized acquisition parameters, MRF can be performed in the presence of inhomogeneous magnetic fields. Flip angle homogeneity can also be incorporated into the dictionary matching process to simultaneously estimate quantitative parameters of the subject and radio frequency coil transmission homogeneity profiles.
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5.发明申请公开(公告)号：US20180203081A1
公开(公告)日：2018-07-19
申请号：US15872449
申请日：2018-01-16
发明人： Ouri Cohen , Bo Zhu , Matthew S. Rosen
CPC分类号： G01R33/4828 , G01R33/50 , G01R33/5608 , G06N3/04 , G06N3/08 , G06N3/084
摘要： Disclosed is a system and method for estimating quantitative parameters of a subject using a magnetic resonance (“MR”) system using a dictionary. The dictionary may include a plurality of signal templates that sparsely sample acquisition parameters used when acquiring data. The acquired data is compared with the dictionary using a neural network. Thus, systems and methods are provided that are more computationally efficient, and have reduced data storage requirements than traditional MRF reconstruction systems and methods.
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6.发明申请公开(公告)号：US20180031667A1
公开(公告)日：2018-02-01
申请号：US15660221
申请日：2017-07-26
发明人： Mathieu Sarracanie , Matthew Rosen , Ouri Cohen , Lionel Broche
IPC分类号： G01R33/565 , G01R33/48 , G01R33/36 , G01R33/561
CPC分类号： G01R33/56563 , G01R33/3614 , G01R33/482 , G01R33/5615 , G01R33/5616 , G01R33/5659
摘要： Systems and methods for magnetic resonance fingerprinting (“MRF”) using highly differentiated trajectories that optimize differentiation between magnetic resonance signal patterns as a function of relaxation time(s) and static magnetic field homogeneity are described. Using the optimized acquisition parameters, MRF can be performed in the presence of inhomogeneous magnetic fields. Flip angle homogeneity can also be incorporated into the dictionary matching process to simultaneously estimate quantitative parameters of the subject and radio frequency coil transmission homogeneity profiles.
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7.发明申请公开(公告)号：US20180210050A1
公开(公告)日：2018-07-26
申请号：US15874961
申请日：2018-01-19
发明人： Matthew Rosen , Christian T. Farrar , Ouri Cohen , Shuning Huang
CPC分类号： G01R33/50 , G01R33/4804 , G01R33/4824 , G01R33/5605
摘要： A system and method of use includes (a) directing a magnetic resonance (MR) system to perform a pulse sequences block in which radio frequency (RF) energy is applied to the subject to substantially saturate magnetization corresponding to an exchangeable proton. The method includes (b), following step (a), acquiring data from the subject with the MR system and (c) repeating step (a) a plurality of times where parameters of the pulse sequence sub-block differ in at least some pulse sequence sub-blocks by at least an amount of RF energy applied to saturate the magnetization. The method further includes (d), after each repetition of step (a), repeating step (b) to acquire data representing signal evolutions from the subject. Additionally, the method includes (e) comparing the signal evolutions with a dictionary database comprising a plurality of different signal evolution templates to determine quantitative chemical exchange or exchangeable proton information of the subject.
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公开(公告)号：US20170299683A1
公开(公告)日：2017-10-19
申请号：US15481977
申请日：2017-04-07
发明人： Ouri Cohen
IPC分类号： G01R33/563 , G01R33/56 , G01R33/48 , G01R33/561
CPC分类号： G01R33/56366 , G01R33/4806 , G01R33/482 , G01R33/4828 , G01R33/50 , G01R33/5601 , G01R33/5616 , G01R33/56308 , G01R33/5635
摘要： Described here are systems and methods for generating quantitative perfusion parameter maps based on different longitudinal relaxation parameter maps that are produced from images acquired using non-selective and selective magnetic resonance imaging (“MRI”) data acquisition techniques.
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公开(公告)号：US20160291107A1
公开(公告)日：2016-10-06
申请号：US15088353
申请日：2016-04-01
发明人： Matthew S. Rosen , Mathieu Sarracanie , Ouri Cohen
IPC分类号： G01R33/48 , G01R33/561 , G01R33/54
摘要： Provided is a system and method for performing a magnetic resonance fingerprinting imaging process. The process includes determining acquisition parameters including at least one of repetition time (TR) or flip angle (FA), selected to control one of a duration and a number of repetitions of for a pulse sequence that samples k-space in a Cartesian acquisition pattern by acquiring an echo train. The process also includes controlling a magnetic resonance imaging (MRI) system to perform the pulse sequence a plurality of times to acquire magnetic resonance fingerprinting (MRF) data corresponding to signals from the subject excited by the pulse sequence. The process also includes estimating quantitative tissue properties of the subject by comparing the MRF data to a database and reconstructing, from the MRF data, at least one image of the subject indicating the estimated quantitative tissue properties.
摘要翻译： 提供了一种用于执行磁共振指纹图像处理的系统和方法。 该过程包括确定包括重复时间（TR）或翻转角（FA）中的至少一个的采集参数，被选择用于控制在笛卡尔采集模式中采样k空间的脉冲序列的持续时间和重复次数之一 通过获取回波列车。 该过程还包括控制磁共振成像（MRI）系统以多次执行脉冲序列以获取对应于由脉冲序列激发的对象的信号的磁共振指纹（MRF）数据。 该过程还包括通过将MRF数据与数据库进行比较来估计受试者的定量组织性质，并从MRF数据重建指示所估计的定量组织性质的受试者的至少一个图像。
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10.发明申请System and Method for Coordinating Use of An Interventional or Implantable Device With External Magnetic Fields 审中-公开用于协调使用具有外部磁场的介入或可植入装置的系统和方法公开(公告)号：US20160077169A1
公开(公告)日：2016-03-17
申请号：US14853662
申请日：2015-09-14
发明人： Ouri Cohen , Jerome L. Ackerman
CPC分类号： G01R33/288 , G01R33/285 , G01R33/287
摘要： A system and method is provided for use with a magnetic resonance imaging (MRI) system to facilitate use of a medical device during operation of the MRI system. The system includes a probe configured to be electrically coupled to a medical device configured to be inserted or implanted into a subject and an analyzer system configured to receive data from the probe and determine resonant frequencies of the medical device using the data. The system also includes a display configured to generate a report of the resonant frequencies of the medical device at least over predicted operating frequencies of the MRI system during an imaging procedure using the MRI system and in the presence of the medical device and indicating any resonant frequencies of the medical device coincident with the predicted operating frequencies of the MRI system during the medical procedure.
摘要翻译： 提供了一种与磁共振成像（MRI）系统一起使用以便于在MRI系统操作期间使用医疗装置的系统和方法。 该系统包括被配置为电耦合到被配置为被插入或植入对象的医疗装置的探针和被配置为从探针接收数据并且使用该数据确定医疗装置的谐振频率的分析器系统。 该系统还包括被配置为在使用MRI系统的成像过程期间以及在存在医疗设备并且指示任何谐振频率的情况下至少在MRI系统的预测工作频率上产生医疗设备的谐振频率的报告的显示器 的医疗装置与医疗过程中MRI系统的预测工作频率一致。
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