专利检索 ap:("The Governing Council of the University of Toronto") AND inv:"Andrei Yudin" 第 1 页

1.

发明申请
Cyclic Amino Acid Molecules And Methods Of Preparing The Same 审中-公开
标题翻译：环状氨基酸分子及其制备方法

公开(公告)号：US20160222062A1

公开(公告)日：2016-08-04

申请号：US14962952

申请日：2015-12-08

申请人： The Governing Council of the University of Toronto

发明人： Andrei Yudin , Ryan Hili

IPC分类号： C07K7/64 , C07D487/04 , C07K5/12 , C07F7/18

CPC分类号： C07K7/64 , C07D487/04 , C07D487/14 , C07F7/1804 , C07K1/003 , C07K1/006 , C07K5/12 , C07K5/123 , C07K5/126

摘要： Macrocyclization of amino acids or linear peptides upon reaction with amphoteric amino aldehydes and isocyanides is provided.

摘要翻译： 提供了与两性氨基醛和异氰酸酯反应时氨基酸或线性肽的大环化。

2.

发明授权
Cyclic amino acid molecules and methods of preparing the same 有权

公开(公告)号：US10385099B2

公开(公告)日：2019-08-20

申请号：US14962952

申请日：2015-12-08

申请人： The Governing Council of the University of Toronto

发明人： Andrei Yudin , Ryan Hili

IPC分类号： C07K7/64 , C07K5/12 , C07F7/18 , C07D487/04 , C07D487/14 , C07K1/00

摘要： Macrocyclization of amino acids or linear peptides upon reaction with amphoteric amino aldehydes and isocyanides is provided.

3.

发明申请
OXADIAZOLE CYCLIC PEPTIDES 审中-公开

公开(公告)号：US20180251496A1

公开(公告)日：2018-09-06

申请号：US15760533

申请日：2016-09-16

申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

发明人： Andrei Yudin , John R. Frost

IPC分类号： C07K7/64 , C07K1/02

摘要： The present invention relates to cyclic amino acid molecules, in particular 1,3,4-oxadiazole containing macrocyclic peptides, and a process to produce the same. The process involves the macrocyclization of amino acids or linear peptides. Specifically, the process comprises reacting an amino acid molecule with an isocyano-iminophosphorane and an aldehyde or a ketone.

4.

发明授权
Oxadiazole cyclic peptides 有权

公开(公告)号：US10703779B2

公开(公告)日：2020-07-07

申请号：US15760533

申请日：2016-09-16

申请人： THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO

发明人： Andrei Yudin , John R. Frost

IPC分类号： C07K7/64 , C07K1/02 , C07D498/18 , C07K7/06

摘要： The present invention relates to cyclic amino acid molecules, in particular 1,3,4-oxadiazole containing macrocyclic peptides, and a process to produce the same. The process involves the macrocyclization of amino acids or linear peptides. Specifically, the process comprises reacting an amino acid molecule with an isocyano-iminophosphorane and an aldehyde or a ketone.