专利检索 ap:("The Hospital for Sick Children" OR "The Governing Council of the University of Toronto") AND inv:"Bebhinn Treanor" 第 1 页

1.

发明申请
NANOPARTICLE PLATFORM FOR ANTIBODY AND VACCINE DELIVERY 审中-公开

公开(公告)号：US20200179532A1

公开(公告)日：2020-06-11

申请号：US16636141

申请日：2018-08-03

申请人： The Hospital for Sick Children , The Governing Council of the University of Toronto

发明人： Jean-Philippe Julien , Taylor Sicard , Anthony Semesi , Bebhinn Treanor , Tiantian Zhao , Edurne Rujas Diez

IPC分类号： A61K47/69 , A61K39/015 , A61K47/68 , C07K14/445

摘要： A fusion protein comprises a nanocage monomer; and an antibody or fragment thereof linked to the nanocage monomer, the antibody or fragment thereof comprising a first member of a binding pair; wherein a plurality of the fusion proteins self-assemble to form a nanocage in which a plurality of the antibodies or fragments thereof decorate the exterior surface of the nanocage, whereby the first member of the binding pair is exposed for interacting with a second member of a binding pair.

2.

发明公开
MULTI-VALENT AND MULTI-SPECIFIC NANOPARTICLE PLATFORMS AND METHODS 审中-公开

公开(公告)号：US20230145060A1

公开(公告)日：2023-05-11

申请号：US17631588

申请日：2020-07-31

申请人： The Hospital for Sick Children , The Governing Council of the University of Toronto

发明人： Jean-Philippe Julien , Edurne Rujas Diez , Bebhinn Treanor , Tiantian Zhao

IPC分类号： A61K39/21 , A61K47/64 , A61K47/68 , A61K39/385 , A61K49/00 , A61P31/18 , C12P21/02

CPC分类号： A61K39/21 , A61K47/64 , A61K47/6803 , A61K39/385 , A61K49/0002 , A61P31/18 , C12P21/02 , A61K2039/6056

摘要： A fusion protein comprises a first nanocage monomer subunit of a nanocage monomer; and a bioactive moiety linked to the first nanocage monomer subunit; wherein the fusion protein self-assembles with a protein comprising a second nanocage monomer subunit to form a nanocage monomer.