专利检索 ap:("The Penn State Research Foundation") AND inv:"Chuanxin CHEN" 第 1 页

1.

发明申请
GENERATION OF PANCREATIC PROGENITOR CELLS AND BETA CELLS FROM HUMAN PLURIPOTENT STEM CELLS 有权

公开(公告)号：US20210324337A1

公开(公告)日：2021-10-21

申请号：US17269233

申请日：2019-08-22

申请人： The Penn State Research Foundation

发明人： Xiaojun LIAN , Chuanxin CHEN

IPC分类号： C12N5/071 , A61K35/39

摘要： Provided are methods, compositions and kits for generating beta cells from pluripotent stem cells under growth-factor free, defined culture conditions. The beta cells can be generated under conditions that are free of animal products. The generated beta cells secrete insulin, not glucagon, and the amount of insulin secreted is dependent upon the level of glucose stimulus.