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公开(公告)号:US20020081616A1
公开(公告)日:2002-06-27
申请号:US09949444
申请日:2001-09-07
发明人: Steven M. Menchen , Linda G. Lee , Charles R. Connell , N. Davis Hershey , Vergine Chakerian , Sam L. Woo , Steven Fung
IPC分类号: C12Q001/68 , C07H021/04
CPC分类号: C07H21/00 , A61K48/00 , C07D311/82 , C09B11/08 , C12Q1/6816 , C12Q1/6869 , Y10S435/968 , Y10S436/80 , Y10T436/143333 , Y10T436/145555 , Y10T436/147777 , C12Q2563/107
摘要: Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting spacially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2null,4null,5null,7null-tetrachloro-4,7-dichloro-5- (and 6-) carboxyfluoresceins. Methods and kits for using the dyes in DNA analysis are provided.
摘要翻译: 提供长波长,窄发射带宽荧光素染料用于检测空间重叠的目标物质。 染料包括4,7-二氯荧光素,特别是2',4',5',7'-四氯-4,7-二氯-5-(和6-)羧基荧光素。 提供了在DNA分析中使用染料的方法和试剂盒。