公开(公告)号：US20170348459A1

公开(公告)日：2017-12-07

申请号：US15455120

申请日：2017-03-09

申请人： The Texas A&M University System

发明人： Venu Varanasi ,  Pranesh Aswath ,  Philip Kramer ,  Megen Velten ,  Azhar Ilyas

IPC分类号： A61L27/32 ,  A61C8/02 ,  C09D1/00 ,  C23C16/22 ,  C04B35/597 ,  A61F2/30 ,  A61L27/10 ,  A61L27/38 ,  A61L27/54 ,  C23C16/50 ,  A61C8/00

摘要： Disclosed are compositions, methods and processes for fabricating and using a device or other implement including a surface or surfaces having a nanoscale or microscale layer or coating of Si—O—N—P. These coatings and/or layers may be continuous, on the surface or discontinuous (e.g., patterned, grooved), and may be provided on silica surfaces, metal (e.g., titanium), ceramic, and combination/hybrid materials. Methods of producing an implantable device, such as a load-bearing or non-load-bearing device, such as a bone or other structural implant device (load-bearing), are also presented. Craniofacial, osteogenic and disordered bone regeneration (osteoporosis) uses and applications of devices that include at least one surface that is treated to include a nanoscale or microscale layer or coating of Si—O—N—P are also provided. Methods of using the treated and/or coated devices to enhance enhanced vascularization and healing at a treated surface of a device in vivo, is also presented.

公开(公告)号：US10828393B2

公开(公告)日：2020-11-10

申请号：US15455120

申请日：2017-03-09

申请人： The Texas A&M University System ,  BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM

发明人： Venu Varanasi ,  Pranesh Aswath ,  Philip Kramer ,  Megen Velten ,  Azhar Ilyas

IPC分类号： A61L27/32 ,  A61L27/54 ,  A61L27/10 ,  A61L27/38 ,  C09D1/00 ,  C04B35/597 ,  C23C16/50 ,  C23C16/22 ,  A61C8/02 ,  A61C8/00 ,  A61F2/30 ,  C23C16/30 ,  C04B35/515 ,  C09D7/60

摘要： Disclosed are compositions, methods and processes for fabricating and using a device or other implement including a surface or surfaces having a nanoscale or microscale layer or coating of Si—O—N—P. These coatings and/or layers may be continuous, on the surface or discontinuous (e.g., patterned, grooved), and may be provided on silica surfaces, metal (e.g., titanium), ceramic, and combination/hybrid materials. Methods of producing an implantable device, such as a load-bearing or non-load-bearing device, such as a bone or other structural implant device (load-bearing), are also presented. Craniofacial, osteogenic and disordered bone regeneration (osteoporosis) uses and applications of devices that include at least one surface that is treated to include a nanoscale or microscale layer or coating of Si—O—N—P are also provided. Methods of using the treated and/or coated devices to enhance enhanced vascularization and healing at a treated surface of a device in vivo, is also presented.