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公开(公告)号：US20090216321A1
公开(公告)日：2009-08-27
申请号：US12437731
申请日：2009-05-08
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2230/0026 , A61F2230/0067 , A61F2230/008 , A61F2230/0095 , A61F2250/0067
摘要： A prosthetic valve includes a support frame, a leaflet attached to the support frame, and a bioactive agent associated with the leaflet. A first free edge of the leaflet permits fluid flow through a body vessel in a first direction and substantially prevents fluid flow through the body vessel in a second, opposite direction. A second free edge of the leaflet at least partially defines an opening for permitting a controlled amount of fluid flow through the body vessel.
摘要翻译： 假体瓣膜包括支撑框架，附接到支撑框架的小叶以及与小叶相关联的生物活性剂。 小叶的第一自由边允许流体沿着第一方向流过身体容器，并且基本上防止流体沿第二相反方向流过身体血管。 叶片的第二自由边缘至少部分地限定了允许受控量的流体流过身体容器的开口。
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公开(公告)号：US07544207B2
公开(公告)日：2009-06-09
申请号：US11244991
申请日：2005-10-06
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2230/0026 , A61F2230/0067 , A61F2230/008 , A61F2230/0095 , A61F2250/0067
摘要： Medical devices with one or more bioactive agents are provided for regulating fluid flow through a body vessel. Medical devices according to the invention can comprise prosthetic valves that include a bioactive agent.
摘要翻译： 提供具有一种或多种生物活性剂的医疗装置用于调节通过身体血管的流体流动。 根据本发明的医疗装置可以包括包括生物活性剂的人造瓣膜。
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公开(公告)号：US07670366B2
公开(公告)日：2010-03-02
申请号：US10820918
申请日：2004-04-08
申请人： Brian C. Case , Jacob A. Flagle , Ram H. Paul , Andrew K. Hoffa , Michael L. Garrison , Joseph F. Obermiller
发明人： Brian C. Case , Jacob A. Flagle , Ram H. Paul , Andrew K. Hoffa , Michael L. Garrison , Joseph F. Obermiller
IPC分类号： A61F2/06
CPC分类号： A61F2/2475 , A61F2/2418 , A61F2/848 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/0026 , A61F2230/0054 , A61F2230/0095
摘要： Implantable medical devices comprising a support frame and a graft member attached to the support frame. The support frame can define one or more structural features that substantially prevent migration of the graft member along the support frame.
摘要翻译： 可植入医疗装置，其包括支撑框架和附接到支撑框架的移植物构件。 支撑框架可以限定一个或多个结构特征，其基本上防止移植构件沿着支撑框架的移动。
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公开(公告)号：US20100030314A1
公开(公告)日：2010-02-04
申请号：US12576481
申请日：2009-10-09
申请人： Brian C. Case , Jacob A. Flagle , Ram H. Paul , Andrew K. Hoffa , Michael L. Garrison , Joseph F. Obermiller
发明人： Brian C. Case , Jacob A. Flagle , Ram H. Paul , Andrew K. Hoffa , Michael L. Garrison , Joseph F. Obermiller
IPC分类号： A61F2/06
CPC分类号： A61F2/2475 , A61F2/2418 , A61F2/848 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/0026 , A61F2230/0054 , A61F2230/0095
摘要： Implantable medical devices comprising a support frame and a graft member attached to the support frame. The support frame can define one or more structural features that substantially prevent migration of the graft member along the support frame.
摘要翻译： 可植入医疗装置，其包括支撑框架和附接到支撑框架的移植物构件。 支撑框架可以限定一个或多个结构特征，其基本上防止移植构件沿着支撑框架的移动。
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公开(公告)号：US07503928B2
公开(公告)日：2009-03-17
申请号：US11582248
申请日：2006-10-17
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/0054 , A61F2230/0067 , A61F2230/008 , A61F2230/0095
摘要： The present invention provides self-expanding or otherwise expandable artificial valve prostheses for deployment within a bodily passageway, such as a vessel or duct of a patient. The valve prostheses include a support structure having an outer frame and supporting a valve leaflet.
摘要翻译： 本发明提供了用于展开在身体通道（例如患者的血管或导管）内的自膨胀或其它可膨胀的人造瓣膜假体。 瓣膜假体包括具有外框架并支撑瓣膜小叶的支撑结构。
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公开(公告)号：US08444687B2
公开(公告)日：2013-05-21
申请号：US12393819
申请日：2009-02-26
申请人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller , John A. DeFord , Joseph W. Roberts
发明人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller , John A. DeFord , Joseph W. Roberts
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
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公开(公告)号：US08613763B2
公开(公告)日：2013-12-24
申请号：US12258757
申请日：2008-10-27
申请人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , John A. DeFord , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller
发明人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , John A. DeFord , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
摘要翻译： 多面医疗装置包括包括线或其它弹性材料并具有一系列弯曲和互连侧的框架。 该装置具有扁平构型和第二折叠构造，其大致蛇形形状。 该装置从输送导管推入管道或容器的内腔，并且可以包括用于锚定目的的一个或多个倒钩。 织物或其他柔性材料如DACRON，PTFE或基于胶原的材料如小肠粘膜下层（SIS）的全部或部分覆盖物可以被缝合或附着到框架上以形成闭塞装置，支架移植物， 或可植入的管腔内瓣膜，例如用于矫正小腿和脚部的无能力的静脉。
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公开(公告)号：US20090048662A1
公开(公告)日：2009-02-19
申请号：US12258757
申请日：2008-10-27
申请人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , John A. DeFord , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller
发明人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , John A. DeFord , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
摘要翻译： 多面医疗装置包括包括线或其它弹性材料并具有一系列弯曲和互连侧的框架。 该装置具有扁平构型和第二折叠构造，其大致蛇形形状。 该装置从输送导管推入管道或容器的内腔，并且可以包括用于锚定目的的一个或多个倒钩。 织物或其他柔性材料如DACRON，PTFE或基于胶原的材料如小肠粘膜下层（SIS）的全部或部分覆盖物可以被缝合或附着到框架上以形成闭塞装置，支架移植物， 或可植入的管腔内瓣膜，例如用于矫正小腿和脚部的无能力的静脉。
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公开(公告)号：US20090157169A1
公开(公告)日：2009-06-18
申请号：US12393819
申请日：2009-02-26
申请人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller , John A. DeFord , Joseph W. Roberts
发明人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller , John A. DeFord , Joseph W. Roberts
IPC分类号： A61F2/06
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
摘要翻译： 多面医疗装置包括包括线或其它弹性材料并具有一系列弯曲和互连侧的框架。 该装置具有扁平构型和第二折叠构造，其大致蛇形形状。 该装置从输送导管推入管道或容器的内腔，并且可以包括用于锚定目的的一个或多个倒钩。 织物或其他柔性材料如DACRON，PTFE或胶原基材料如小肠粘膜下层（SIS）的全部或部分覆盖物可以使用热或压力焊接压接，粘合剂或 形成闭塞装置，支架移植物或可植入的腔内瓣膜的其它技术，例如用于矫正小腿和脚部的无能力的静脉。
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公开(公告)号：US07520894B2
公开(公告)日：2009-04-21
申请号：US11165600
申请日：2005-06-22
申请人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller , John A. DeFord , Joseph W. Roberts
发明人： Dusan Pavcnik , Frederick S. Keller , Josef Rosch , Thomas A. Osborne , Brian L. Bates , Christopher G. Dixon , Andrew K. Hoffa , Raymond B. Leonard, II , Joseph F. Obermiller , John A. DeFord , Joseph W. Roberts
CPC分类号： A61F2/01 , A61F2/2418 , A61F2/2475 , A61F2002/018 , A61F2220/0008 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2230/001 , A61F2230/0023 , A61F2230/0026 , A61F2230/0054 , A61F2230/0058 , A61F2230/0095 , Y10S623/901
摘要： A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
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