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1.发明授权
公开(公告)号：US5258436A
公开(公告)日：1993-11-02
申请号：US764027
申请日：1991-09-23
CPC分类号： A61K9/2866 , A61K9/282
摘要： A water dispersible polymeric film-forming particulate composition for use in coating pharmaceuticals and foods or the like, produced by freeze-drying an aqueous solution of water-soluble cellulose acetate as the film-forming polymer, a plasticizer, and optionally a pigment, is described. The product mixes readily with water to form an aqueous dispersion which is applied in the conventional manner to solid pharmaceutical forms.
摘要翻译： 通过冷冻干燥水溶性乙酸纤维素水溶液作为成膜聚合物，增塑剂和任选的颜料制备的用于涂覆药物和食品等的水分散性聚合物成膜颗粒组合物是 描述。 该产物容易与水混合以形成以常规方式施用于固体药物形式的水分散体。
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2.发明授权Film-forming composition and use for coating pharmaceuticals, foods and the like 失效成膜组合物和用于涂覆药物，食品等的用途
公开(公告)号：US5206030A
公开(公告)日：1993-04-27
申请号：US484309
申请日：1990-02-26
IPC分类号： A61K9/28
CPC分类号： A61K9/28 , A61K9/2866
摘要： A water-dispersible, particulate film-forming composition is produced by blending a mixture of particles of water-soluble cellulose acetate; pigment particles, a plasticizer for the water-soluble cellulose acetate, and a surfactant. The composition is useful as a film-forming material for coating solid pharmaceutical forms.
摘要翻译： 水分散性颗粒成膜组合物通过将水溶性乙酸纤维素的混合物混合而制得; 颜料颗粒，用于水溶性乙酸纤维素的增塑剂和表面活性剂。 该组合物可用作涂覆固体药物形式的成膜材料。
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3.发明授权
公开(公告)号：US5248516A
公开(公告)日：1993-09-28
申请号：US758141
申请日：1991-09-12
CPC分类号： A61K9/2866 , A61K9/282
摘要： A water dispersible film-forming particulate composition for use in coating pharmaceuticals and foods or the like, produced by freeze-drying an aqueous solution of a water-soluble polymer, a plasticizer, and optionally a pigment, is described. The product mixes readily with water to form an aqueous dispersion which is applied in the conventional manner to solid pharmaceutical forms.
摘要翻译： 描述了通过冷冻干燥水溶性聚合物，增塑剂和任选的颜料的水溶液而制备的用于涂覆药物和食品等的水分散性成膜颗粒组合物。 该产物容易与水混合以形成以常规方式施用于固体药物形式的水分散体。
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4.发明授权
公开(公告)号：US5486364A
公开(公告)日：1996-01-23
申请号：US290457
申请日：1994-08-15
CPC分类号： A61K9/205 , Y10S514/96 , Y10S514/961
摘要： A solid dosage form, such as a pharmaceutical tablet, containing a rapidly hydratable konjac glucomannan sustained release excipient such as clarified konjac, cryogenically ground konjac and plasticized konjac. The method of making the tablets by compressing excipient and pharmaceutically active ingredient as dry powders.
摘要翻译： 固体剂型，例如含有快速水合的魔芋葡甘聚糖持久释放赋形剂如澄清的魔芋，低温地魔土并且增塑魔芋的药物片剂。 通过将赋形剂和药物活性成分压制成干粉来制造片剂的方法。
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公开(公告)号：US5725886A
公开(公告)日：1998-03-10
申请号：US311800
申请日：1994-09-26
CPC分类号： C08J3/005 , A61K9/1652 , C08L1/02 , C08J2300/14 , C08J2301/00 , C08L1/28
摘要： A particulate co-processed unattrited microcrystalline cellulose:hydrocolloid composition wherein the respective components are present in a weight ratio of from about 99:1 to 70:30. The composition is useful as a spheronizing agent for producing spheroids of uniform size and sphericity and having high drug loadings. The composition is produced by drying a slurry of the microcrystalline cellulose in an aqueous solution of the hydrocolloid. The preferred hydrocolloid is methylcellulose.
摘要翻译： 一种颗粒状协同处理的未结晶微晶纤维素：水胶体组合物，其中各组分以约99:1至70:30的重量比存在。 该组合物可用作生产具有均匀尺寸和球形度并且具有高药物负载量的球状体的球形化剂。 通过将微晶纤维素的浆液干燥在水胶体的水溶液中来制备组合物。 优选的水胶体是甲基纤维素。
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公开(公告)号：US4693896A
公开(公告)日：1987-09-15
申请号：US785317
申请日：1985-10-07
CPC分类号： A61K31/60 , A61K9/2866
摘要： A coated aspirin tablet, which is capable of being disintegrated quickly in gastric fluid, containing a thin film of plasticized ethylcellulose. The ethylcellulose thin film coating represents less than about 2 wt % of the coated tablet weight and is the dried residue of an aqueous ethylcellulose dispersion that is spray-coated onto the tablet.
摘要翻译： 涂有阿司匹林片剂，其能够在胃液中快速分解，含有增塑乙基纤维素的薄膜。 乙基纤维素薄膜涂层占涂布片重量的小于约2重量％，并且是将水性乙基纤维素分散体的干燥残余物喷涂在片剂上。
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