公开(公告)号：US20110002986A1

公开(公告)日：2011-01-06

申请号：US12828556

申请日：2010-07-01

申请人： Thomas Durig ,  Yuda Zong

发明人： Thomas Durig ,  Yuda Zong

IPC分类号： A61K9/48 ,  A23L1/00 ,  A61K47/00

CPC分类号： A61K9/4891 ,  A61K47/44

摘要： The present invention relates to formulations for use as enteric coatings. More particularly, the present invention relates to a formulation comprising a blend of food grade ingredients that can be readily dispersed in water. This dispersion exhibits low viscosity and can easily be coated onto solid dosage forms through spraying and the like to provide an enteric coating on the solid dosage form.

摘要翻译： 本发明涉及用作肠溶衣的制剂。 更具体地说，本发明涉及包含可容易地分散在水中的食品级成分的混合物的制剂。 该分散体显示出低粘度，并且可以通过喷雾等容易地涂布到固体剂型上，以在固体剂型上提供肠溶衣。

公开(公告)号：US20090252767A1

公开(公告)日：2009-10-08

申请号：US12291723

申请日：2008-11-13

申请人： Thomas Durig ,  Derek Ronell Malone ,  Yuda Zong

发明人： Thomas Durig ,  Derek Ronell Malone ,  Yuda Zong

IPC分类号： A61K9/00 ,  A61K47/38 ,  A61K47/04 ,  A61K47/10 ,  C09D193/02

CPC分类号： A61K9/282 ,  A61K9/286 ,  A61K9/2866 ,  A61K9/4891

摘要： The present invention relates to formulations for use as enteric coatings. More particularly, the present invention relates to a formulation comprising a dry blend of food grade ingredients that can be readily dispersed in water. This dispersion exhibits low viscosity and can easily be coated onto solid dosage forms through spraying and the like to provide an enteric coating on the solid dosage form.

摘要翻译： 本发明涉及用作肠溶衣的制剂。 更具体地说，本发明涉及一种包含可容易地分散在水中的食品级成分的干混物的制剂。 该分散体显示出低粘度，并且可以通过喷雾等容易地涂布到固体剂型上，以在固体剂型上提供肠溶衣。

公开(公告)号：US06592901B2

公开(公告)日：2003-07-15

申请号：US09977785

申请日：2001-10-15

申请人： Thomas Durig ,  Ronald Haywood Hall ,  Richard A. Salzstein

发明人： Thomas Durig ,  Ronald Haywood Hall ,  Richard A. Salzstein

IPC分类号： A61K914

CPC分类号： A61K9/2054

摘要： A pharmaceutical dosage form composition is composed of an ethylcellulose that has an ethoxyl range lower limit of 49.6%, an a viscosity of less than 53 cps and at least one active pharmaceutical ingredient. This dosage form is highly compressible and compactible forming harder tables or pellets with better release retardation than comparable prior art tablets.

摘要翻译： 药物剂型组合物由乙氧基范围下限为49.6％，粘度小于53cps的乙基纤维素和至少一种活性药物成分组成。 该剂型是高度可压缩和可压缩的，形成具有比现有技术的片剂更好的释放阻滞的较硬的桌子或丸剂。

公开(公告)号：US08968456B2

公开(公告)日：2015-03-03

申请号：US12869272

申请日：2010-08-26

申请人： Thomas Durig ,  Divya Tewari

发明人： Thomas Durig ,  Divya Tewari

IPC分类号： C08L1/08 ,  A61K9/28 ,  A23G3/34

CPC分类号： A61K9/2866 ,  A23G3/343 ,  A23G2200/00 ,  A23G2200/06 ,  A61K9/288

摘要： The present invention relates to a film coating composition used for film coating pharmaceutical tablets, nutritional supplements, confectionary forms and the like. The film coating composition comprises a water soluble film former such as hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose, starches, modified starches and the like and one or more hydrophobic compounds, such as metal salt of higher fatty acids, higher fatty alcohol, natural wax either from vegetable, animal origin or synthetic wax. Optionally, the film coating composition may include plasticizers, colorants, such as pigments and/or flow aids.

摘要翻译： 本发明涉及用于薄膜包衣药片，营养补品，糖果形式等的薄膜包衣组合物。 薄膜包衣组合物包含水溶性成膜剂，例如羟丙基纤维素，羟丙基甲基纤维素，羟乙基纤维素，淀粉，改性淀粉等，以及一种或多种疏水化合物，例如高级脂肪酸的金属盐，高级脂肪醇，天然蜡， ，动物来源或合成蜡。 任选地，膜包衣组合物可以包括增塑剂，着色剂，例如颜料和/或流动助剂。

公开(公告)号：US20080305166A1

公开(公告)日：2008-12-11

申请号：US12151695

申请日：2008-05-08

申请人： Thomas Durig

发明人： Thomas Durig

IPC分类号： A61K9/20

CPC分类号： A61K9/0056 ,  A61K9/1652 ,  A61K31/00

摘要： A rapidly disintegrating, orally administered tablet or compressed dosage form, comprising ethylcellulose (EC) as a directly compressible binder which enhances tablet robustness as manifested by improved strength, lower friability, lower hygroscopicity and yet, hydrophobic nature notwithstanding, does not retard disintegration, but shortens disintegration time or is disintegration time neutral when co-formulated with disintegrants and other water-soluble excipients such as sugar alcohols.

摘要翻译： 包含乙基纤维素（EC）作为直接可压缩粘合剂的快速崩解的口服给药片剂或压缩剂型，其通过改善的强度，较低的脆性，较低的吸湿性表现出增强片剂的坚固性，并且尽管如此，疏水性不会阻滞崩解，但是 当与崩解剂和其它水溶性赋形剂如糖醇共配制时，缩短崩解时间或崩解时间中性。