公开(公告)号：US20070203444A1

公开(公告)日：2007-08-30

申请号：US11741081

申请日：2007-04-27

申请人： Thomas FELT ,  Bruce GIBBS ,  Brian HOLMES

发明人： Thomas FELT ,  Bruce GIBBS ,  Brian HOLMES

IPC分类号： A61M37/00

CPC分类号： A61M1/3693 ,  A61M1/0218 ,  A61M1/0231 ,  A61M1/3633 ,  A61M1/3696 ,  A61M1/3698 ,  A61M1/38 ,  A61M2205/331 ,  B04B5/0428 ,  B04B5/0442 ,  B04B13/00 ,  B04B2013/006

摘要： A method and apparatus for separating a volume of whole blood contained in a separation bag into at least three components comprising centrifuging the separation bag so as to separate therein a first inner layer comprising plasma, a second intermediate layer comprising platelets, a third intermediate layer comprising lymphocytes, monocytes and granulocytes and a fourth outer layer comprising red blood cells, transferring, into a plasma component bag connected to the separation bag, a plasma component and transferring into a mononuclear cell component bag a mononuclear cell components.

摘要翻译： 一种将包含在分离袋中的全血的体积分成至少三个组分的方法和装置，包括离心分离袋，以便在其中分离包含等离子体的第一内层，包含血小板的第二中间层，第三中间层， 淋巴细胞，单核细胞和粒细胞，以及包含红细胞的第四外层，转移到与分离袋连接的血浆成分袋中的血浆成分，并将单核细胞成分转移到单核细胞成分袋中。

公开(公告)号：US20100081196A1

公开(公告)日：2010-04-01

申请号：US12633461

申请日：2009-12-08

申请人： Thomas FELT ,  Bruce GIBBS ,  Brian HOLMES

发明人： Thomas FELT ,  Bruce GIBBS ,  Brian HOLMES

IPC分类号： B01D21/26 ,  C12N5/078

CPC分类号： A61M1/3693 ,  A61M1/0218 ,  A61M1/0231 ,  A61M1/3633 ,  A61M1/3696 ,  A61M1/3698 ,  A61M1/38 ,  A61M2205/331 ,  B04B5/0428 ,  B04B5/0442 ,  B04B13/00 ,  B04B2013/006

摘要： A method for separating a volume of whole blood contained in a separation bag into at least three components comprising centrifuging the separation bag so as to separate therein a first inner layer comprising plasma, a second intermediate layer comprising platelets, a third intermediate layer comprising lymphocytes, monocytes and granulocytes and a fourth outer layer comprising red blood cells, transferring, into a plasma component bag connected to the separation bag, a plasma component and transferring into a mononuclear cell component bag a mononuclear cell components.

摘要翻译： 一种将包含在分离袋中的全血的体积分成至少三个组分的方法，包括离心分离袋，以便在其中分离包含血浆的第一内层，包含血小板的第二中间层，包含淋巴细胞的第三中间层， 单核细胞和粒细胞以及包含红细胞的第四外层，转移到与分离袋连接的血浆成分袋中的血浆成分，并将单核细胞成分转移到单核细胞成分袋中。

公开(公告)号：US20080093312A1

公开(公告)日：2008-04-24

申请号：US11956696

申请日：2007-12-14

申请人： Brian HOLMES ,  Peter PIHLSTEDT ,  Geert VAN WAEG

发明人： Brian HOLMES ,  Peter PIHLSTEDT ,  Geert VAN WAEG

IPC分类号： B01D21/26

CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/3696 ,  A61M1/3698 ,  A61M2205/331 ,  B01D21/262 ,  B01D2221/10 ,  B04B5/0428 ,  B04B5/0442 ,  B04B13/00 ,  B04B2013/006

摘要： A method for separating a volume of a composite liquid into at least a first component and a second component is performed in a centrifuge cooperating with a separation bag containing the volume of composite liquid. The separation bag is connected to at least a first component bag and a second component bag. The separation bag is spun so as to centrifuge the volume of composite liquid and cause the sedimentation of the at least first and second components. When the at least first and second components have sedimented, the first component is transferred at least one first transfer flow rate into the first component bag. When the first component has been transferred into the first component bag, the second component is transferred into the intermediate component bag at least one second transfer flow rate that is different from the at least one first transfer flow rate.

摘要翻译： 在与包含复合液体体积的分离袋配合的离心机中进行将复合液体的体积分离成至少第一成分和第二成分的方法。 分离袋连接到至少第一组分袋和第二组分袋。 旋转分离袋以离心复合液体的体积并引起至少第一和第二组分的沉降。 当至少第一和第二组分沉淀时，第一组分将至少一个第一转移流速转移到第一组分袋中。 当第一组分已被转移到第一组分袋中时，将第二组分转移到中间组分袋中至少一个不同于至少一个第一转移流速的第二转移流速。

公开(公告)号：US20070084807A1

公开(公告)日：2007-04-19

申请号：US11611682

申请日：2006-12-15

申请人： Brian HOLMES ,  Johan-Petter HAGSTROM ,  Per-Olov LUNDBERG ,  Geert VAN WAEG ,  Peter NORDGREN

发明人： Brian HOLMES ,  Johan-Petter HAGSTROM ,  Per-Olov LUNDBERG ,  Geert VAN WAEG ,  Peter NORDGREN

IPC分类号： C02F1/38

CPC分类号： B04B13/00 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/025 ,  A61M1/26 ,  A61M1/262 ,  A61M1/3633 ,  A61M1/3639 ,  A61M1/3641 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/3698 ,  A61M2205/331 ,  B04B5/0428 ,  B04B5/0442 ,  B04B2005/045 ,  B04B2005/0478 ,  B04B2013/006

摘要： A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the separation space of the rotor and first and second collection containers connected to the separation container by a first and a second tubes. The tubes are adapted to be disposed in operative relationship with the valve members so that flow through the tubes may be controlled thereby. Three components of the composite fluid may be separated therefrom by the present system and two components may be moved to the collection containers. The container set may further include a third collection container connected to the separation container by a tube, and a third component may thus be moved to this third container.

公开(公告)号：US20070084806A1

公开(公告)日：2007-04-19

申请号：US11611567

申请日：2006-12-15

申请人： Brian HOLMES ,  Johan-Petter HAGSTROM ,  Per-Olov LUNDBERG ,  Geert VAN WAEG ,  Peter NORDGREN

发明人： Brian HOLMES ,  Johan-Petter HAGSTROM ,  Per-Olov LUNDBERG ,  Geert VAN WAEG ,  Peter NORDGREN

IPC分类号： C02F1/38

CPC分类号： B04B13/00 ,  A61M1/0209 ,  A61M1/0218 ,  A61M1/025 ,  A61M1/26 ,  A61M1/262 ,  A61M1/3633 ,  A61M1/3639 ,  A61M1/3641 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/3698 ,  A61M2205/331 ,  B04B5/0428 ,  B04B5/0442 ,  B04B2005/045 ,  B04B2005/0478 ,  B04B2013/006

摘要： A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the separation space of the rotor and first and second collection containers connected to the separation container by a first and a second tubes. The tubes are adapted to be disposed in operative relationship with the valve members so that flow through the tubes may be controlled thereby. Three components of the composite fluid may be separated therefrom by the present system and two components may be moved to the collection containers. The container set may further include a third collection container connected to the separation container by a tube, and a third component may thus be moved to this third container.

摘要翻译： 一种将复合流体分离成其组成部分的系统，包括：具有分离空间的转子和设置在其上的至少两个阀构件的离心机和具有适于设置在转子的分离空间中的分离容器的容器组 以及通过第一和第二管连接到分离容器的第一和第二收集容器。 管适于与阀构件成可操作的关系，从而可以控制通过管的流动。 复合流体的三个组分可以通过本系统与其分离，并且两个组分可以移动到收集容器中。 容器组还可以包括通过管连接到分离容器的第三收集容器，并且因此第三组分可以移动到第三容器。