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公开(公告)号：US06225101B1
公开(公告)日：2001-05-01
申请号：US09337386
申请日：1999-06-21
IPC分类号： C12N912
CPC分类号： C12N9/1205
摘要： The present invention provides a threonine/tyrosine kinase, Myt1, that phosphorylates the cyclin-dependent kinase, Cdc2, to provide regulation of the cell cycle at the G2/M interphase. Also included are polynucleotides encoding Myt1 polypeptide and antibodies that bind to Myt1. Methods of modulating Myt1 for preventing premature entry of the cell into mitosis or to accelerate entry into mitosis are also provided, as are methods for identifying agents that modulate Myt1.
摘要翻译： 本发明提供苏氨酸/酪氨酸激酶Myt1，其使细胞周期蛋白依赖性激酶Cdc2磷酸化，以提供G2 / M中间期细胞周期的调节。 还包括编码Myt1多肽的多核苷酸和结合Myt1的抗体。 还提供了调节Myt1以防止细胞过早进入有丝分裂或加速进入有丝分裂的方法，以及用于鉴定调节Myt1的药剂的方法。
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公开(公告)号：US4226271A
公开(公告)日：1980-10-07
申请号：US917589
申请日：1978-06-21
申请人： Thomas R. Coleman
发明人： Thomas R. Coleman
摘要： Disclosed herein is a drum type debarker for the debarking of logs and the like and there is provided a drive means for rotating the drum. The drum sits in a saddle that includes vehicle tires, and a drive mechanism is provided for rotating certain of the tires or wheels so as to rotate the drum. There is also provided a flange section on the drum that has vertically mounted tires arranged in engagement therewith for holding the drum in place.
摘要翻译： 本文公开了一种用于剥离原木等的滚筒式剥皮机，并且设置有用于使滚筒旋转的驱动装置。 滚筒位于包括车辆轮胎的马鞍中，并且提供驱动机构用于旋转某些轮胎或轮子以使滚筒旋转。 在滚筒上还设有一个凸缘部分，该凸缘部分具有与其配合的垂直安装的轮胎，用于将滚筒保持在适当位置。
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公开(公告)号：US06387642B2
公开(公告)日：2002-05-14
申请号：US09846922
申请日：2001-04-30
IPC分类号： C12Q148
CPC分类号： C12N9/1205
摘要： The present invention provides a threonine/tyrosine kinase, Myt1, that phosphorylates the cyclin-dependent kinase, Cdc2, to provide regulation of the cell cycle at the G2/M interphase. Also included are polynucleotides encoding Myt1 polypeptide and antibodies that bind to Myt1. Methods of modulating Myt1 for preventing premature entry of the cell into mitosis or to accelerate entry into mitosis are also provided, as are methods for identifying agents that modulate Myt1.
摘要翻译： 本发明提供苏氨酸/酪氨酸激酶Myt1，其使细胞周期蛋白依赖性激酶Cdc2磷酸化，以提供G2 / M中间期细胞周期的调节。 还包括编码Myt1多肽的多核苷酸和结合Myt1的抗体。 还提供了调节Myt1以防止细胞过早进入有丝分裂或加速进入有丝分裂的方法，以及用于鉴定调节Myt1的药剂的方法。
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公开(公告)号：US6020194A
公开(公告)日：2000-02-01
申请号：US942001
申请日：1997-10-01
CPC分类号： C12N9/1205
摘要： The present invention provides a threonine/tyrosine kinase, Myt1, that phosphorylates the cyclin-dependent kinase, Cdc2, to provide regulation of the cell cycle at the G2/M interphase. Also included are polynucleotides encoding Myt1 polypeptide and antibodies that bind to Myt1. Methods of modulating Myt1 for preventing premature entry of the cell into mitosis or to accelerate entry into mitosis are also provided, as are methods for identifying agents that modulate Myt1.
摘要翻译： 本发明提供苏氨酸/酪氨酸激酶Myt1，其使细胞周期蛋白依赖性激酶Cdc2磷酸化，以提供G2 / M中间期细胞周期的调节。 还包括编码Myt1多肽的多核苷酸和结合Myt1的抗体。 还提供了调节Myt1以防止细胞过早进入有丝分裂或加速进入有丝分裂的方法，以及用于鉴定调节Myt1的药剂的方法。
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