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公开(公告)号：US4861584A
公开(公告)日：1989-08-29
申请号：US99960
申请日：1987-09-23
CPC分类号： A61K8/4973 , A61K8/26 , A61K8/416 , A61Q17/00 , Y10S514/862 , Y10S514/949
摘要： An allergen absorbent and blocking aerosol composition for topical application to the skin comprises a highly activated organophilic clay of the smectite type, ion exchanged with a quaternary ammonium compound having aryl or alkyl groups in the range of from 10 to 22 carbon atoms, and a vehicle comprising one or more long-chain hydrocarbons or volatile silicone oils. The composition is preferably in the form of an aerosol composition additionally comprising an aerosol propellant. The composition is applied to the skin, preferably by spraying, to block and absorb the allergenic oils of toxic plants such as poison ivy and the like.
摘要翻译： 用于局部施用于皮肤的过敏原吸收剂和阻塞气溶胶组合物包括蒙脱石型的高活性亲有机粘土，与具有10至22个碳原子的芳基或烷基的季铵化合物进行离子交换， 包括一种或多种长链烃或挥发性硅油。 组合物优选为另外包含气溶胶推进剂的气溶胶组合物的形式。 组合物优选通过喷雾施用于皮肤，以阻断和吸收有毒植物如毒藤等的变应原油。
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公开(公告)号：US5017361A
公开(公告)日：1991-05-21
申请号：US390862
申请日：1989-08-08
CPC分类号： A61K8/4973 , A61K8/26 , A61K8/416 , A61Q17/00 , Y10S514/862
摘要： An allergen absorbent and blocking aerosol composition for topical application to the skin comprises a highly activated organophilic clay of the smectite type, ion exchanged with a quaternary ammonium compound having aryl or alkyl groups in the range of from 10 to 22 carbon atoms, and a vehicle comprising one or more long-chain hydrocarbons or volatile silicone oils. The composition is preferably in the form of an aerosol composition additionally comprising an aerosol propellant. The composition is applied to the skin, preferably by spraying, to block and absorb the allergenic oils of toxic plants such as poison ivy and the like.
摘要翻译： 用于局部施用于皮肤的过敏原吸收剂和阻塞气溶胶组合物包括蒙脱石型的高活性亲有机粘土，与具有10至22个碳原子的芳基或烷基的季铵化合物进行离子交换， 包括一种或多种长链烃或挥发性硅油。 组合物优选为另外包含气溶胶推进剂的气溶胶组合物的形式。 组合物优选通过喷雾施用于皮肤，以阻断和吸收有毒植物如毒藤等的变应原油。
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公开(公告)号：US06331295B1
公开(公告)日：2001-12-18
申请号：US09391389
申请日：1999-09-08
申请人： Anthony A. Schulz
发明人： Anthony A. Schulz
IPC分类号： A61K748
CPC分类号： A61F13/8405 , A61L15/18
摘要： Skin irritation, such as diaper rash, appearing when the skin is allowed to remain in contact with proteolytic enzymes found in feces is prevented by inactivating the fecal proteolytic enzymes by contact with organophilic clays. The organophilic clays are applied to the skin in areas likely to come into contact with feces or to garments such as diapers. A composition suitable for practicing the method of the invention comprises an amount of an organophilic clay effective to inactivate irritating fecal proteolytic enzymes dispersed in a pharmaceutically acceptable non-toxic dermatological vehicle. A fabric incorporating organophilic clay, preferably dispersed in a matrix of a superabsorbent polymer is useful for preparing diapers for infants that can help to prevent skin irritation by fecal enzymes.
摘要翻译： 通过与亲有机粘土接触来灭活粪便蛋白水解酶，可防止皮肤刺激，例如当皮肤与粪便中发现的蛋白水解酶保持接触时出现尿布疹。 将亲有机粘土施用于可能与粪便或诸如尿布的衣服接触的区域中的皮肤。 适用于实施本发明方法的组合物包含一定量的有效地灭活分散在药学上可接受的无毒皮肤病学载体中的刺激性粪便蛋白水解酶的有机物质粘土。 包含亲有机粘土的织物，优选分散在超吸收聚合物的基质中可用于制备可帮助防止粪便酶引起的皮肤刺激的婴儿尿布。
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公开(公告)号：US5702709A
公开(公告)日：1997-12-30
申请号：US423099
申请日：1995-04-18
IPC分类号： A61K8/25 , A61K8/26 , A61K8/34 , A61K8/37 , A61K9/00 , A61K9/70 , A61K47/02 , A61Q17/00 , A61K9/48
CPC分类号： A61K8/26 , A61K47/02 , A61K8/34 , A61K8/37 , A61K9/0014 , A61K9/7015 , A61Q17/00 , A61K2800/75 , Y10S514/862
摘要： A lotion capable of protecting the skin from the effects of exposure to irritants and allergens, particularly those produced by toxic plants such as poison ivy, has the following composition, wherein the proportions are by weight: ______________________________________ organophilic clay 3.0-10.0% volatile alcoholic solvent 20.0-30.0% cosmetically acceptable inert 15.0-25.0% emollient vehicle thickener 2.0-10.0% water q.s.p. 100.0% ______________________________________
摘要翻译： 能够保护皮肤免受暴露于刺激物和过敏原的影响的洗剂，特别是毒性植物如毒藤中产生的乳液具有以下组成，其中比例为重量百分比： - 亲油性粘土3.0-10.0％挥发性酒精 溶剂20.0-30.0％ - 化妆品可接受的惰性15.0-25.0％ - 润肤剂 - 增稠剂2.0-10.0％ - 水qsp 100.0％ -
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公开(公告)号：US6051749A
公开(公告)日：2000-04-18
申请号：US956457
申请日：1997-10-23
申请人： Anthony A. Schulz
发明人： Anthony A. Schulz
CPC分类号： A61F13/8405 , A61L15/18
摘要： Skin irritation, such as diaper rash, appearing when the skin is allowed to remain in contact with proteolytic enzymes found in feces is prevented by inactivating the fecal proteolytic enzymes by contact with organophilic clays. The organophilic clays are applied to the skin in areas likely to come into contact with feces or to garments such as diapers. A composition suitable for practicing the method of the invention comprises an amount of an organophilic clay effective to inactivate irritating fecal proteolytic enzymes dispersed in a pharmaceutically acceptable non-toxic dermatological vehicle. A fabric incorporating organophilic clay, preferably dispersed in a matrix of a superabsorbent polymer is useful for preparing diapers for infants that can help to prevent skin irritation by fecal enzymes.
摘要翻译： 通过与亲有机粘土接触来灭活粪便蛋白水解酶，可防止皮肤刺激，例如当皮肤与粪便中发现的蛋白水解酶保持接触时出现尿布疹。 将亲有机粘土施用于可能与粪便或诸如尿布的衣服接触的区域中的皮肤。 适用于实施本发明方法的组合物包含一定量的有效地灭活分散在药学上可接受的无毒皮肤病学载体中的刺激性粪便蛋白水解酶的有机物质粘土。 包含亲有机粘土的织物，优选分散在超吸收聚合物的基质中可用于制备可帮助防止粪便酶引起的皮肤刺激的婴儿尿布。
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公开(公告)号：US5869033A
公开(公告)日：1999-02-09
申请号：US631119
申请日：1996-04-12
申请人： Anthony A. Schulz
发明人： Anthony A. Schulz
CPC分类号： A61F13/8405 , A61L15/18
摘要： Skin irritation, such as diaper rash, appearing when the skin is allowed to remain in contact with proteolytic enzymes found in feces is prevented by inactivating the fecal proteolytic enzymes by contact with organophilic clays. The organophilic clays are applied to the skin in areas likely to come into contact with feces or to garments such as diapers. A composition suitable for practicing the method of the invention comprises an amount of an organophilic clay effective to inactivate irritating fecal proteolytic enzymes dispersed in a pharmaceutically acceptable non-toxic dermatological vehicle. A fabric incorporating organophilic clay, preferably dispersed in a matrix of a superabsorbent polymer is useful for preparing diapers for infants that can help to prevent skin irritation by fecal enzymes.
摘要翻译： 通过与亲有机粘土接触来灭活粪便蛋白水解酶，可防止皮肤刺激，例如当皮肤与粪便中发现的蛋白水解酶保持接触时出现尿布疹。 将亲有机粘土施用于可能与粪便或诸如尿布的衣服接触的区域中的皮肤。 适用于实施本发明方法的组合物包含一定量的有效地灭活分散在药学上可接受的无毒皮肤病学载体中的刺激性粪便蛋白水解酶的有机物质粘土。 包含亲有机粘土的织物，优选分散在超吸收聚合物的基质中可用于制备可帮助防止粪便酶引起的皮肤刺激的婴儿尿布。
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