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公开(公告)号:US20120195958A1
公开(公告)日:2012-08-02
申请号:US13256262
申请日:2010-03-26
申请人: Timothy O'Brien , Udo Greiser , Faisal Sharif , Sean Hynes , Jim Crowley
发明人: Timothy O'Brien , Udo Greiser , Faisal Sharif , Sean Hynes , Jim Crowley
IPC分类号: A61K9/127 , A61M27/00 , B05D5/00 , A61K31/7088
CPC分类号: A61L27/54 , A61K9/127 , A61K9/1272 , A61K47/6957 , A61L29/16 , A61L31/16 , A61L2300/258 , A61L2300/626
摘要: The present invention relates to implantable devices, which are coated or coatable with liposomes. The present invention further relates to liposomes encapsulating nucleic acids termed lipoplexes, to methods for the manufacture and coating of such implantable devices, and to the use of such implantable devices to improve treatment of patients with coronary artery disease or other vascular diseases and cancers.
摘要翻译: 本发明涉及可与脂质体包被或可涂覆的可植入装置。 本发明还涉及包封称为脂质复合物的核酸的脂质体,用于制造和涂覆这种可植入装置的方法,以及使用这种可植入装置来改善冠状动脉疾病或其它血管疾病和癌症患者的治疗。