公开(公告)号：US20240270811A1

公开(公告)日：2024-08-15

申请号：US18289934

申请日：2022-05-12

Applicant: Tokyo University of Science Foundation

Inventor： Chikamasa Yamashita

IPC: C07K14/605 ,  A61K9/00 ,  A61K38/00 ,  A61P25/24 ,  C07K1/107

CPC classification number: C07K14/605 ,  A61K9/0043 ,  A61P25/24 ,  C07K1/1077 ,  A61K38/00

Abstract: A glycosylated neuropeptide derivative, having a neuropeptide sequence, a cell-penetration accelerating sequence, an endosomal-escape accelerating sequence, and a sugar chain.

公开(公告)号：US20170253643A1

公开(公告)日：2017-09-07

申请号：US15507403

申请日：2015-09-02

Applicant: Tokyo University of Science Foundation

Inventor： Chikamasa Yamashita ,  Jun-Ichiro Oka ,  Michiko Horiguchi ,  Sachie Sasaki-Hamada

IPC: C07K14/605 ,  A61K38/26 ,  A61K9/00

CPC classification number: C07K14/605 ,  A61K9/0043 ,  A61K38/00 ,  A61K38/095 ,  A61K38/2264 ,  A61K38/2271 ,  A61K38/26 ,  A61K38/28 ,  C07K19/00

Abstract: A centrally-acting peptide derivative, including a centrally-acting portion, a cell-penetrating sequence portion, and an endosomal-escape portion.

公开(公告)号：US20210163567A1

公开(公告)日：2021-06-03

申请号：US17172408

申请日：2021-02-10

Applicant: TOKYO UNIVERSITY OF SCIENCE FOUNDATION

Inventor： Chikamasa Yamashita ,  Jun-Ichiro Oka ,  Michiko Horiguchi ,  Sachie Sasaki-Hamada

IPC: C07K14/605 ,  A61K38/26 ,  C07K19/00 ,  A61K38/22 ,  A61K38/28 ,  A61K38/095 ,  A61K9/00

Abstract: A method of delivering a centrally-acting peptide derivative, and method of treating a neuropsychiatric disorder.